HsaINT0177867 @ hg19
Intron Retention
Gene
ENSG00000107731 | UNC5B
Description
unc-5 homolog B (C. elegans) [Source:HGNC Symbol;Acc:12568]
Coordinates
chr10:73057666-73060749:+
Coord C1 exon
chr10:73057666-73057847
Coord A exon
chr10:73057848-73058868
Coord C2 exon
chr10:73058869-73060749
Length
1021 bp
Sequences
Splice sites
5' ss Seq
CCGGTGAGT
5' ss Score
10.9
3' ss Seq
GCCCTCCTTCCCTCTGCCAGGTA
3' ss Score
11.07
Exon sequences
Seq C1 exon
ACACCTGCTGGCTCCCTGGACACTCTCTGCTCTGCCCCTGGCAGCACTGTCACCACCCAGCTGGGACCTTATGCCTTCAAGATCCCACTGTCCATCCGCCAGAAGATATGCAACAGCCTAGATGCCCCCAACTCACGGGGCAATGACTGGCGGATGTTAGCACAGAAGCTCTCTATGGACCG
Seq A exon
GTGAGTATCCCAAACCACAGCCCATCCCCATCTGCCTTCGTCCTCAAGGTCTCACAGGGGCAGGCAGGGCAGGCAGCCTGACAGCCACGACCATCTCCCAGACCAGCTGCCCTTTTGCCACCATTTGTGGCAAATCAGCAACTCAGGATTGGATATGCAAAGTTCAAGAATACTGCTCCCTTGAGGAGCATCATGCTCAGAGCACTGGTCCTTGAGCCAGGCAGACTCTCAGACCCTGCTCTTTTCCCATTGTGTGGGGATAATGCTCCACCTGCCCATCTCACCGAACAGCAGGAGACTCAAAGCCAGGGCATCAGCTTGGTGCCATCATTGTCAGCACCTGGTATCTAGGACAGAGAATGTGCTGCGAGATGCTTGCTGACTGACCAAGATACACTTTGGTGTCAAAACTCCTTTGGAGAACCTCAAATGCTGGATAAGTGCTGGATAAATATAAGGCCAATGATAATAAATATTATACTTATTGAAAGATGTGTAATAAACCTGCATTGAGTCTCAAAAAATAAATAAATAAAATATGCTTTAGATAAGACATTTTACTAGAAATGAATAGGACTTACAAAGATGGCTAAGGCTTTATTCCTCCTATCAGGGGAGTTCATGGGAGCAGGAGGGAACACGGGTGGGAGGAATGACCACATGCTAGACGTGGTCATTCTCTCTTGGGGCCAGTGTCTTTCAATGATAATAATGATGATGATGAACAAGATGGTTACATGCTAGAGACAACGCTAGACCCTTACTTTATATGATCTTGGATCTTGCTGAGCGGTAACTGGCATTGTTCCCATTTTAGAGACAAGGAGACTGAGATTCTGAGCCATAGGTTCTGAATTGCCGAGAGCCACACAGACTGCAGCACAGTAGCTGCAATTCAGACCCAGGACAGTGGGACACCAAAGCTCACAGCCTTCCCACTTCCCCTTGTGCCCCTTCACCTCCAGGCTCCGGGGAGGGGCTAAGTGCTTGGGAACCTCAGTGCCCTCCTTCCCTCTGCCAG
Seq C2 exon
GTACCTGAATTACTTTGCCACCAAAGCGAGCCCCACGGGTGTGATCCTGGACCTCTGGGAAGCTCTGCAGCAGGACGATGGGGACCTCAACAGCCTGGCGAGTGCCTTGGAGGAGATGGGCAAGAGTGAGATGCTGGTGGCTGTGGCCACCGACGGGGACTGCTGAGCCTCCTGGGACAGCGGGCTGGCAGGGACTGGCAGGAGGCAGGTGCAGGGAGGCCTGGGGCAGCCTCCTGATGGGGATGTTTGGCCTCTGCTTCCTCCCAGTTCACAGCCAGAGTTGCCTCTCCTCCTCCTCTTCCCCAACCCCCAGACCATGACCAGCCTTAGAAAATCCATGTACTCTGTTGTTAGAGGGCCCAGAGTTCCTTCTCCACCCCCGCTCTCTCTCTCTTGGCCTGAGATCTCTGTGCAGGAACCAAGATGGGGCTGAAGCCTCTGGAGGCAGTTGGTTGGGGGCGGGCAGGCAGGAGGCCCTCCCTCCACCCCCCCACCCTCAGCCCGGCAACTTCTGGGTTCCATGGGTTTTAGTTCCGTTCTCGTTTTCTTCCTCCGTTATTGATTTCTCCTTTCTCCCTAAGCCCCCTTCTGCTTCCACGCCCTTTTCCTCTTTGAAGAGTCAAGTACAATTCAGACAAACTGCTTTCTCCTGTCCAAAAGCAAAAAGGCAAAGGAAAGAAAGAAAGCTTCAGACCGCTAGTAAGGCTCAAAGAAGAAGAAAAACACCAAAACCACAAGGGAAAAGAAAAACCCAGTTTCTTAGGAAACGCAAACGATTTATTATCCAGATTATTTGGATAAGTCCTTTTTAAGAAAAAAAAAGAAAATGAAAAACAACACAAAAAAAATAGAAAACTCTTTTCTTGAGTGTGGATGAGAATGGGCACGCTCACACTTCTGGCCAGGAGTGAATGTGCCTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTACATGTACGCGTGTGCATTGAGGAGAGAGAGACTGAACAGAGAGTACTTTGCTGCTAACGAATCCATCTTGGACTAAATTCTGACAAGGCCTCAGTTTCCCCAGTTGTGCAGGGAGTAGGTCAGACAGGGTTTTCACTGTCTAGATTTAGCTGGTTAGATTTTCCTCTAAAATCTTAAGCAGATGCTGAATCCATAAAGCCAAGGAGTGCTGAGGGCTGGAGTGGGTGGGCCCTCCCTCCCACAGCCCCAGGGAGATACATCTGGACTCCTGGGAATCTGGATTAAGAAAGTTGGGATGAAAGAGGAGGACTGCTCAGGCCAGTTGTGAGCCAGGGAGAATGTTCCAGTCTGGTTTTGGTCTGGTGGCTCCTAGAAAGGGATGTGGCCCAGAAGTGGGACTCAAACAGAGAGATGAAGTAGGGGAGGGGAGTCCTCCACGGGCATCTCTCTCCTGGCGGCTGGATAGCTTTACCCTAGGGTGGGGCCAGCCCTGACACCCTCATCCCCTCCTCAGCCCAGCAGCCTCTAGAGCAGCGTGGTGCTCTCTTGATGGCCAGGAATCCAGAATCTGCCCTTCCCCAACCTTGGTTTCTCCTTCTGTAAAGCAGAGTGATGGCTGAGAAGTCCTCTCTAGCTGCAGAAGCCTGAGCTTCCCGGTGTCAGTCAGCTCTGCAACGTGGGAGCCTTGGAGGCGGGTGGCCTGGCTGTGCTTCATATGCCCAGGAGTGGAGAAGGAGGCTGAGAAGCTGGTTTCCCAGCTCTGATCTCCACAGGCACCTCCTATAACCCTCCTCTCACCCACCCCGCTACGGTCTGAGAGATCTGAAATAACCTTTCCCAGTGGGCAGGGTTGCCAGGGTTGAGGGGACAGCACATACCACCCCCACCCAACCTGTTCGAGGGGCCCTGCATGGCACGGGATGAGTCCC
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000107731-UNC5B:NM_170744:16
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
Alternative protein isoforms
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.036
Domain overlap (PFAM):
C1:
PF0053117=Death=PU(34.2=44.3)
A:
NA
C2:
PF0053117=Death=PD(64.6=91.1)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GGCAATGACTGGCGGATGTTA
R:
AAGAGGAGGAGGAGAGGCAAC
Band lengths:
344-1365
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)