HsaINT0177873 @ hg19
Intron Retention
Gene
ENSG00000107731 | UNC5B
Description
unc-5 homolog B (C. elegans) [Source:HGNC Symbol;Acc:12568]
Coordinates
chr10:73048325-73048747:+
Coord C1 exon
chr10:73048325-73048489
Coord A exon
chr10:73048490-73048714
Coord C2 exon
chr10:73048715-73048747
Length
225 bp
Sequences
Splice sites
5' ss Seq
AAAGTGAGT
5' ss Score
8.4
3' ss Seq
CCCTTTATTTCCCTTGACAGATA
3' ss Score
11.54
Exon sequences
Seq C1 exon
TCGATGGGGCGTGGACGGAGTGGAGCAAGTGGTCAGCCTGCAGCACTGAGTGTGCCCACTGGCGTAGCCGCGAGTGCATGGCGCCCCCACCCCAGAACGGAGGCCGTGACTGCAGCGGGACGCTGCTCGACTCTAAGAACTGCACAGATGGGCTGTGCATGCAAA
Seq A exon
GTGAGTCACAGGGAAGGTGGGGCCCTGGGGGTGGGGACTCTGGAGCCATGTAAGGGTCCCCCAAACCCGGCCCCATGCCTCAGTGCCCAGCCTGCAGCACGGCAGTCCTCAGGGCCTCTGTCCCCCCACCACATCCATCATCTCATCTCATCCTTCCCATTGCCTTCTCTGCCACCCTTTCCCTGTCACCTATGTCATTGTCTTTCCCTTTATTTCCCTTGACAG
Seq C2 exon
ATAAGAAAACTCTAAGCGACCCCAACAGCCACC
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000107731-UNC5B:NM_170744:7
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.167
Domain overlap (PFAM):
C1:
PF150281=PTCRA=FE(48.2=100),PF0009014=TSP_1=WD(100=85.7)
A:
NA
C2:
PF150281=PTCRA=FE(9.6=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GATGGGGCGTGGACGGAG
R:
CTGTTGGGGTCGCTTAGAGTT
Band lengths:
191-416
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)