HsaINT0181157 @ hg19
Intron Retention
Gene
ENSG00000165816 | VWA2
Description
von Willebrand factor A domain containing 2 [Source:HGNC Symbol;Acc:24709]
Coordinates
chr10:116032499-116037806:+
Coord C1 exon
chr10:116032499-116032693
Coord A exon
chr10:116032694-116037672
Coord C2 exon
chr10:116037673-116037806
Length
4979 bp
Sequences
Splice sites
5' ss Seq
CAGGTAAGA
5' ss Score
10.77
3' ss Seq
GTTACAACCCCTTGGCACAGGTG
3' ss Score
3.84
Exon sequences
Seq C1 exon
AGGAGGGCGCACGGAGACGGAACTTGCTCTGAAATACCTTCTGCACAGAGGGTTGCCTGGAGGCAGAAATGCTTCTGTGCCCCAGATCCTCATCATCGTCACTGATGGGAAGTCCCAGGGGGATGTGGCACTGCCATCCAAGCAGCTGAAGGAAAGGGGTGTCACTGTGTTTGCTGTGGGGGTCAGGTTTCCCAG
Seq A exon
GTAAGAGCCTCAGTCACCCTGGATCAGCCCTCAGGTGGTCAGCCTGGGGATCGTGACATGGCCATGGGAGGGAAGGGAGGGGACTGGAAGAGCCGTCCAGGTCCTTCCCTGGATCTGTCTTTTCCTCACTTTGCCATTTTGACTCCAGTGCACAGGAAGCTCCAATCTTTTGGAGCCTGTATTTGCATTGATTTTGGTTTTGTTTGAAAACTCAGTTGCAAGTGCCAGAAACTCTGCTGAAATTTATTTGGGCAAAAATGGAAATTCATGGAGTGATCTCATTCACTGGGTGGGATGGGGGTCCCTCAGGGTGTGCAGGAGCCAGGGACTTCAGTGTCATCGAGATTCTTCCACATATCTCTGCTGTTCTCTGCCTGTTGCCTCCTCTCGTACCCTGACTTTATTAGGAAGCTGGAACTGGAGCTGTGGACGGTGCCCAGCTCACGTCTTCAGAGCTCCACCCTGGAGAGAAAAGACCCCTTTCCACAGTTTAACAATCCAATAAAATATTCTAATCAGCCTGAGGCAGAGCCCACTCTTGGGGCCAAGGGAGTAGGAGTCTGACTGGCCACTCCCCCTTTACCCCATTTGTCTAGCTGCTGGGCAAATAGGCTTTCCTAGAAGAGAGGAGGGTACAGATCCTTAATGCTCTCAAACCAAAAAATGGACGTCACTTATGCCATGGACCAATAGTTATTGTGAGCGTTAAGTGAAATGACTCTGGTCTGGGCACTGTGTTTGCACACAGAAATCTCTTCATTAATTTTAGTACATTATTTAATTTCTCAGTTAATAAATCCAGGGTTGTCTTTCTCATGCTGGGCATTATTCTAGGTGCTTAGAATACAGAGACAATAATACAAAGTCCCTGCCCTCATGGAGTTTCCATTCTCAGAAAGGAACTAGATAATAAATAAATACATAATATAATTTCAGGTGGAAGTAAAATGCAAAAGGGAAAAATAAAGTAGGGTAAGAGGCTAAAGAATGATGGGGAATAGAGAGGAAAGCTATTTTAGTTTGGGTGGTCAGTCAAGGCTTCTTTGAGAAATTGATTTTTGAGCAGAAACTTGAGTGAAGTGAGGAGTAAGCCTTCCAAATATCAGGGGAAGGCAGGGCAAAGCAGGCAGGTGGGTGGTAAGTACAAAGGCCCTGGGGCAGCAGGTAGGCTGGCGAGTTATAGGAAGGAACAGCCAGACGGCCAGGGAGGGGCGGAAGCCCAGCAAGCAAGTGGCAGAAACACAAGAAGTAAGGGTGGAAGAGCCAGGAGTCAGCCACAGAGACTTGGTGGGCATGGAGAAGATGTTAGTTTATTGTGAGTAGGATGACAGACAGCCTTTGGAGGGTTTTAAGCAGGGGAATGATATCTTCAGAGAATCACATTGGCTGCTGTGTACGAAATAGACTGACAGGATAGGGGTGGGAGAGGAAATAGTAAGGGGAGAGGGGAAACTGATTAGGAGGCCTTTGGCATGGCTCACAAAAGAGATCATGGTGGCTCCTAGAGGGAAGCAGCTGCAGCCTCGACTTAGGATATGTTTGTTGTTTGTTGTTGTTTTTGAGACAGCCTCGCTTTGTCACCCAGGCTGGAGTGCAGTGGCGCCATCTCAGCTCACTGCAACCTCCGCCTCCTGGGTTCAAGCGATTCTCATGCTTCAGCCTTCTGAGTAGCTGGGATTATATGTGCATACCACCACACCTGTGCACGCCACCACACCTGGCTACTTTTTTTTTTTTTTAAATAGAGATAGGGTTTCACCATGTTGGCCAGGCTAGTCTTGAACTCCTGGCTTCAAGTGACCCACCCGTCTCAGCCTTCCATAGTGCTGGGATTACAGGCGTGAGCCACTGCGCCTGGCGTTGGCTTAGGATATGTTTTGAAGGCAGAGCAGTGAGCGGCCGCCACTGAATTGGAGGTGGGTGTGTGAGAGAAGAATTGAGGATTTTGACTTGAGCCCCAGAGTGAATAGTGGTGCCATCTCCCGACATGGGAAAGATGACAACGGGGGAAGAGCACGGGACATTGTGTTCTGTTTCAGACAGAGGAAGTTTGCGGTGCACATTGTACAGCTCAGTGTGGGAGCCGAGCAGACAGTTGGGTGTGAGAATCTGGAGCATGGAGGAGGGGACAGGCATGGAGATTGAAATTTGAGGTGGTTTTTAAATCTGATATAAGGTCACCTAGGTAGTGGGGACAGGGAGAGAAGATGACCAACGGGCCAGCAAGTGCAGGTCAGAGAGAGGAAGAAGATAGAGTGATGGAGACTAAAGAGCGGCCAGTAAGGTGGGGACATCCAGGATTGTGCCATGTCCTGGAAATGGTGATGACATCATTGTCATCAATCATTGTGATCAGCAAGTTGGCATTTAACACAGCCTGCCTTAGCCTTCATTGGCTCATTTTGTCTTCTCAAATATAGGCAATACAAACTCCTGGAGAGAGGAGAGAGGGACTTTGCCTCATGGCCCTCTGCCCGCCGTTTCCCACATTGTGCCAGACACAGTGCCTTGAGCATAGCCATTGCCAAAGATTTGTCCATGAGGGTAGAACCCACCACACGGTGGGAATCCCTGTCTCCTTCCAGTGCTTTCTTCTTCAGCAGGTAGCTGGAACAGTGCCTCTCAAACTGGACCAGTATTTTGTTTTTTTGGTTTTTTTTCCCCCAGATACACCATGGACTGATAACTTTTTAAAAATACAATAAAAATGAGGCCGGGCATGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCCAAGGATGGTGGATTACTTGAGGTCAGGAGTTTGAAACCAGCCTGGCAAACAGGATGAAACCCTATCTCTACTAACAATATAAAAATTAGCCAGGCATGGTGGTGGGTGCCTGTAATCCCAGCTACCCAGGAGGCTAGGGCAAGAGAGTCACTTGAACCCAGGAAGCAGAGGTTACAGTGAGCCGAGATTACGCCACTGCAGTCCAGCCTGGGTGACAGAGGGTGACTCCGTCTCATAAAACAAAAATAAATTAATTAGGGGAAAAATGAAATAAACACAATATAAATTCAAATGTTTATTATTTGATTCAGCAGACATAAAATGACTGTCTCATCGCTGTCCAGTTAGTTTGTCAGTGTTTCAGTGTCTGCGCTTGTCCCCTCTGCACCAGCGTTTAATGCTTAGGGAGCTGCTCTGCCCACCCATTGCTCTTTGAGCAGCCATGGCCTAGAGAGATGAGAAGCCATTCCTTGGGAGGGGGATGGCCTGAGCTGAGGGCCATGTAGGGCTCCCAGGACCACCTGACCCACCCCTCCCCACTCCCACCAAAGGGCTGAGTCGCTGTTGCTCACTGGTTCTCAACGTGTGCTCCCTGGATGCAGTATCTTCGTCACCTGGGAGCCTGCTGGAAACGCACAGCCTGTGGCCCCACACCACTGAATCAGAAACTCAGAGTCAGAGAGCCTTGGTCTGCTCTTCATCCTGCCTTCAGTGACTCTGATGCCCACCAGAGTTTGAGGGTCACTGCCAAGGGCAGCGTGAAACTCTACAAGCAATAAAGCAAAAAAACTGATACTGGTTCAGTCTCTACTTTTATTTTTTTGAGACAGGGTCCCGCTCTGTCACCCAGGCTGGAATGCAGTGGCACGATCATGGCTAACTGCAGCCCTGACCTCCTGGGCTCAAGTGATCCTCCCACCTCAGCCACCCAAGTAGCTGAAGTAGCTGGGAATACAGATGTCTGCCACGACACCCAGCAATTTTTTTTTTTTTTTTTTTTTTTTTTGTAGAGACAGGGTTTCACTGTGTTGCCCAGGCTGGTCTCAAACTCCTAAGCTTGAGGGATTCTCCCGCCTCGGCCTCCCAAAGTACTGGGATAACAGGCGTGAGCCACTGCACCTGGTCTCTTTCCGCCTTTTGAGCCCCTTCTCTGACAGTTCTCAGCTCTGGCTCAGCATCTGAATTACCTGGCAGCTTGTAAGAAAGTCCATTGCAGGGCTGGGGGGCTCCAGGGCTGGCAGCACTGCCTGCAGACCGTGGCTGTGCAACGCCTCCCCTGTGCACATGTGCCCTCAGGGCTCAGTCCTGGGTCCTGGGAGGAGAATCTGTTTTATGTGCATTCAGAGGAGAATGGGAAGTTTTACAGACCTGAATTTTAGAAATGAATGGGATTTTTGCCCTATCGTCAAACCTTGGTCCACCCTGATGACTTTTCAAGGACAGGATTCTTCTAGATACATTACTGACTGCACGTCTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTCTGGAGACAGACTCTCACTCTGTTGCCCAGGCTGGATTGCAGTGGCACAATCTCGGCTCACTGCATCCTCCACCTCCCAGGTTCAAGTGGCTCTCCTGTCTCAGCCTCCCAAGTAGCTGGAACTACAGGCACCCACCACCACACCCAGCTAATTTTTGTATTTTTAGTAGAGATGGGGTTTCATCATGTTAGCTAGGCTGGTCCCAAACTCCTGACCTCAAGTGATCCACCCACCTCGGCCTCCCAAAGTGCTGGGATTAGGCGTGAGCCACCACACCCCCCCTCCGACTGTGTGTCTTCTTAAAATGAGGTTTCTCAACATCGCCTAACCCTTTCTTCATGTCCTAGTGTCACCATCTGTACATCATTTTCCTCCTGGCACAAACAGCGCTGCCCTATGGCTATCGAGGTGTGCTGGCCGCTTCCTCTAGATGGCCTCCTATTGCTGGCCTTGGAGTTCTTACGTCCATTGTTTATCATTCCTCAGTCTTTTTTTCTGTTACCAGCTATGCTTGCTTGTTCTTTGCTTGCTGTCACCTCGAACCACTTTCTTTCATTTCCATTCCGGTTAACTGTTTTCCTCACCAGCTATGGGTCTGACAAAACCAGACACTAAATCTGTGCTGCCATCCACAAGGAACCCACGGCCTAGAAGATGAGGGGGCAGGAGGAGGGTGGGTATAGGACCACAAGCTGTTACAACCCCTTGGCACAG
Seq C2 exon
GTGGGAGGAGCTGCATGCACTGGCCAGCGAGCCTAGAGGGCAGCACGTGCTGTTGGCTGAGCAGGTGGAGGATGCCACCAACGGCCTCTTCAGCACCCTCAGCAGCTCGGCCATCTGCTCCAGCGCCACGCCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000165816-VWA2:NM_198496:6
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.045 A=NA C2=0.022
Domain overlap (PFAM):
C1:
PF0009223=VWA=FE(37.8=100)
A:
NA
C2:
PF0009223=VWA=PD(19.2=71.7)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)