HsaINT0181157 @ hg38
Intron Retention
Gene
ENSG00000165816 | VWA2
Description
von Willebrand factor A domain containing 2 [Source:HGNC Symbol;Acc:HGNC:24709]
Coordinates
chr10:114272740-114278047:+
Coord C1 exon
chr10:114272740-114272934
Coord A exon
chr10:114272935-114277913
Coord C2 exon
chr10:114277914-114278047
Length
4979 bp
Sequences
Splice sites
5' ss Seq
CAGGTAAGA
5' ss Score
10.77
3' ss Seq
GTTACAACCCCTTGGCACAGGTG
3' ss Score
3.84
Exon sequences
Seq C1 exon
AGGAGGGCGCACGGAGACGGAACTTGCTCTGAAATACCTTCTGCACAGAGGGTTGCCTGGAGGCAGAAATGCTTCTGTGCCCCAGATCCTCATCATCGTCACTGATGGGAAGTCCCAGGGGGATGTGGCACTGCCATCCAAGCAGCTGAAGGAAAGGGGTGTCACTGTGTTTGCTGTGGGGGTCAGGTTTCCCAG
Seq A exon
GTAAGAGCCTCAGTCACCCTGGATCAGCCCTCAGGTGGTCAGCCTGGGGATCGTGACATGGCCATGGGAGGGAAGGGAGGGGACTGGAAGAGCCGTCCAGGTCCTTCCCTGGATCTGTCTTTTCCTCACTTTGCCATTTTGACTCCAGTGCACAGGAAGCTCCAATCTTTTGGAGCCTGTATTTGCATTGATTTTGGTTTTGTTTGAAAACTCAGTTGCAAGTGCCAGAAACTCTGCTGAAATTTATTTGGGCAAAAATGGAAATTCATGGAGTGATCTCATTCACTGGGTGGGATGGGGGTCCCTCAGGGTGTGCAGGAGCCAGGGACTTCAGTGTCATCGAGATTCTTCCACATATCTCTGCTGTTCTCTGCCTGTTGCCTCCTCTCGTACCCTGACTTTATTAGGAAGCTGGAACTGGAGCTGTGGACGGTGCCCAGCTCACGTCTTCAGAGCTCCACCCTGGAGAGAAAAGACCCCTTTCCACAGTTTAACAATCCAATAAAATATTCTAATCAGCCTGAGGCAGAGCCCACTCTTGGGGCCAAGGGAGTAGGAGTCTGACTGGCCACTCCCCCTTTACCCCATTTGTCTAGCTGCTGGGCAAATAGGCTTTCCTAGAAGAGAGGAGGGTACAGATCCTTAATGCTCTCAAACCAAAAAATGGACGTCACTTATGCCATGGACCAATAGTTATTGTGAGCGTTAAGTGAAATGACTCTGGTCTGGGCACTGTGTTTGCACACAGAAATCTCTTCATTAATTTTAGTACATTATTTAATTTCTCAGTTAATAAATCCAGGGTTGTCTTTCTCATGCTGGGCATTATTCTAGGTGCTTAGAATACAGAGACAATAATACAAAGTCCCTGCCCTCATGGAGTTTCCATTCTCAGAAAGGAACTAGATAATAAATAAATACATAATATAATTTCAGGTGGAAGTAAAATGCAAAAGGGAAAAATAAAGTAGGGTAAGAGGCTAAAGAATGATGGGGAATAGAGAGGAAAGCTATTTTAGTTTGGGTGGTCAGTCAAGGCTTCTTTGAGAAATTGATTTTTGAGCAGAAACTTGAGTGAAGTGAGGAGTAAGCCTTCCAAATATCAGGGGAAGGCAGGGCAAAGCAGGCAGGTGGGTGGTAAGTACAAAGGCCCTGGGGCAGCAGGTAGGCTGGCGAGTTATAGGAAGGAACAGCCAGACGGCCAGGGAGGGGCGGAAGCCCAGCAAGCAAGTGGCAGAAACACAAGAAGTAAGGGTGGAAGAGCCAGGAGTCAGCCACAGAGACTTGGTGGGCATGGAGAAGATGTTAGTTTATTGTGAGTAGGATGACAGACAGCCTTTGGAGGGTTTTAAGCAGGGGAATGATATCTTCAGAGAATCACATTGGCTGCTGTGTACGAAATAGACTGACAGGATAGGGGTGGGAGAGGAAATAGTAAGGGGAGAGGGGAAACTGATTAGGAGGCCTTTGGCATGGCTCACAAAAGAGATCATGGTGGCTCCTAGAGGGAAGCAGCTGCAGCCTCGACTTAGGATATGTTTGTTGTTTGTTGTTGTTTTTGAGACAGCCTCGCTTTGTCACCCAGGCTGGAGTGCAGTGGCGCCATCTCAGCTCACTGCAACCTCCGCCTCCTGGGTTCAAGCGATTCTCATGCTTCAGCCTTCTGAGTAGCTGGGATTATATGTGCATACCACCACACCTGTGCACGCCACCACACCTGGCTACTTTTTTTTTTTTTTAAATAGAGATAGGGTTTCACCATGTTGGCCAGGCTAGTCTTGAACTCCTGGCTTCAAGTGACCCACCCGTCTCAGCCTTCCATAGTGCTGGGATTACAGGCGTGAGCCACTGCGCCTGGCGTTGGCTTAGGATATGTTTTGAAGGCAGAGCAGTGAGCGGCCGCCACTGAATTGGAGGTGGGTGTGTGAGAGAAGAATTGAGGATTTTGACTTGAGCCCCAGAGTGAATAGTGGTGCCATCTCCCGACATGGGAAAGATGACAACGGGGGAAGAGCACGGGACATTGTGTTCTGTTTCAGACAGAGGAAGTTTGCGGTGCACATTGTACAGCTCAGTGTGGGAGCCGAGCAGACAGTTGGGTGTGAGAATCTGGAGCATGGAGGAGGGGACAGGCATGGAGATTGAAATTTGAGGTGGTTTTTAAATCTGATATAAGGTCACCTAGGTAGTGGGGACAGGGAGAGAAGATGACCAACGGGCCAGCAAGTGCAGGTCAGAGAGAGGAAGAAGATAGAGTGATGGAGACTAAAGAGCGGCCAGTAAGGTGGGGACATCCAGGATTGTGCCATGTCCTGGAAATGGTGATGACATCATTGTCATCAATCATTGTGATCAGCAAGTTGGCATTTAACACAGCCTGCCTTAGCCTTCATTGGCTCATTTTGTCTTCTCAAATATAGGCAATACAAACTCCTGGAGAGAGGAGAGAGGGACTTTGCCTCATGGCCCTCTGCCCGCCGTTTCCCACATTGTGCCAGACACAGTGCCTTGAGCATAGCCATTGCCAAAGATTTGTCCATGAGGGTAGAACCCACCACACGGTGGGAATCCCTGTCTCCTTCCAGTGCTTTCTTCTTCAGCAGGTAGCTGGAACAGTGCCTCTCAAACTGGACCAGTATTTTGTTTTTTTGGTTTTTTTTCCCCCAGATACACCATGGACTGATAACTTTTTAAAAATACAATAAAAATGAGGCCGGGCATGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCCAAGGATGGTGGATTACTTGAGGTCAGGAGTTTGAAACCAGCCTGGCAAACAGGATGAAACCCTATCTCTACTAACAATATAAAAATTAGCCAGGCATGGTGGTGGGTGCCTGTAATCCCAGCTACCCAGGAGGCTAGGGCAAGAGAGTCACTTGAACCCAGGAAGCAGAGGTTACAGTGAGCCGAGATTACGCCACTGCAGTCCAGCCTGGGTGACAGAGGGTGACTCCGTCTCATAAAACAAAAATAAATTAATTAGGGGAAAAATGAAATAAACACAATATAAATTCAAATGTTTATTATTTGATTCAGCAGACATAAAATGACTGTCTCATCGCTGTCCAGTTAGTTTGTCAGTGTTTCAGTGTCTGCGCTTGTCCCCTCTGCACCAGCGTTTAATGCTTAGGGAGCTGCTCTGCCCACCCATTGCTCTTTGAGCAGCCATGGCCTAGAGAGATGAGAAGCCATTCCTTGGGAGGGGGATGGCCTGAGCTGAGGGCCATGTAGGGCTCCCAGGACCACCTGACCCACCCCTCCCCACTCCCACCAAAGGGCTGAGTCGCTGTTGCTCACTGGTTCTCAACGTGTGCTCCCTGGATGCAGTATCTTCGTCACCTGGGAGCCTGCTGGAAACGCACAGCCTGTGGCCCCACACCACTGAATCAGAAACTCAGAGTCAGAGAGCCTTGGTCTGCTCTTCATCCTGCCTTCAGTGACTCTGATGCCCACCAGAGTTTGAGGGTCACTGCCAAGGGCAGCGTGAAACTCTACAAGCAATAAAGCAAAAAAACTGATACTGGTTCAGTCTCTACTTTTATTTTTTTGAGACAGGGTCCCGCTCTGTCACCCAGGCTGGAATGCAGTGGCACGATCATGGCTAACTGCAGCCCTGACCTCCTGGGCTCAAGTGATCCTCCCACCTCAGCCACCCAAGTAGCTGAAGTAGCTGGGAATACAGATGTCTGCCACGACACCCAGCAATTTTTTTTTTTTTTTTTTTTTTTTTTGTAGAGACAGGGTTTCACTGTGTTGCCCAGGCTGGTCTCAAACTCCTAAGCTTGAGGGATTCTCCCGCCTCGGCCTCCCAAAGTACTGGGATAACAGGCGTGAGCCACTGCACCTGGTCTCTTTCCGCCTTTTGAGCCCCTTCTCTGACAGTTCTCAGCTCTGGCTCAGCATCTGAATTACCTGGCAGCTTGTAAGAAAGTCCATTGCAGGGCTGGGGGGCTCCAGGGCTGGCAGCACTGCCTGCAGACCGTGGCTGTGCAACGCCTCCCCTGTGCACATGTGCCCTCAGGGCTCAGTCCTGGGTCCTGGGAGGAGAATCTGTTTTATGTGCATTCAGAGGAGAATGGGAAGTTTTACAGACCTGAATTTTAGAAATGAATGGGATTTTTGCCCTATCGTCAAACCTTGGTCCACCCTGATGACTTTTCAAGGACAGGATTCTTCTAGATACATTACTGACTGCACGTCTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTCTGGAGACAGACTCTCACTCTGTTGCCCAGGCTGGATTGCAGTGGCACAATCTCGGCTCACTGCATCCTCCACCTCCCAGGTTCAAGTGGCTCTCCTGTCTCAGCCTCCCAAGTAGCTGGAACTACAGGCACCCACCACCACACCCAGCTAATTTTTGTATTTTTAGTAGAGATGGGGTTTCATCATGTTAGCTAGGCTGGTCCCAAACTCCTGACCTCAAGTGATCCACCCACCTCGGCCTCCCAAAGTGCTGGGATTAGGCGTGAGCCACCACACCCCCCCTCCGACTGTGTGTCTTCTTAAAATGAGGTTTCTCAACATCGCCTAACCCTTTCTTCATGTCCTAGTGTCACCATCTGTACATCATTTTCCTCCTGGCACAAACAGCGCTGCCCTATGGCTATCGAGGTGTGCTGGCCGCTTCCTCTAGATGGCCTCCTATTGCTGGCCTTGGAGTTCTTACGTCCATTGTTTATCATTCCTCAGTCTTTTTTTCTGTTACCAGCTATGCTTGCTTGTTCTTTGCTTGCTGTCACCTCGAACCACTTTCTTTCATTTCCATTCCGGTTAACTGTTTTCCTCACCAGCTATGGGTCTGACAAAACCAGACACTAAATCTGTGCTGCCATCCACAAGGAACCCACGGCCTAGAAGATGAGGGGGCAGGAGGAGGGTGGGTATAGGACCACAAGCTGTTACAACCCCTTGGCACAG
Seq C2 exon
GTGGGAGGAGCTGCATGCACTGGCCAGCGAGCCTAGAGGGCAGCACGTGCTGTTGGCTGAGCAGGTGGAGGATGCCACCAACGGCCTCTTCAGCACCCTCAGCAGCTCGGCCATCTGCTCCAGCGCCACGCCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000165816:ENST00000392982:6
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.045 A=NA C2=0.022
Domain overlap (PFAM):
C1:
PF0009223=VWA=FE(37.8=100)
A:
NA
C2:
PF0009223=VWA=PD(19.2=71.7)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains