HsaINT0181158 @ hg19
Intron Retention
Gene
ENSG00000165816 | VWA2
Description
von Willebrand factor A domain containing 2 [Source:HGNC Symbol;Acc:24709]
Coordinates
chr10:116037673-116038610:+
Coord C1 exon
chr10:116037673-116037806
Coord A exon
chr10:116037807-116038477
Coord C2 exon
chr10:116038478-116038610
Length
671 bp
Sequences
Splice sites
5' ss Seq
CAGGTAAGA
5' ss Score
10.77
3' ss Seq
GGTGTGTGTTGTGGACACAGACT
3' ss Score
3.82
Exon sequences
Seq C1 exon
GTGGGAGGAGCTGCATGCACTGGCCAGCGAGCCTAGAGGGCAGCACGTGCTGTTGGCTGAGCAGGTGGAGGATGCCACCAACGGCCTCTTCAGCACCCTCAGCAGCTCGGCCATCTGCTCCAGCGCCACGCCAG
Seq A exon
GTAAGATCTTCCAGCCTGGAGGGAGTGGAAGTGCCATGTGGGGTCGGGGAGGGCTCCCTGAGGCAAGAGGTCAGGACCCAGGAGCCTCCCAAGGATGGAGGGCAGGCAAGAGAAACAGAGACCGGCAGCCTCCACCCTGGATGCTCTGCGTCTCCCTGTGCCCTGCCCTGTGGGTTTCCCAGCTGGGAGCCCCGAGCTTGTCTTCATGGAGGTAGAGGGGCCCAGGGTTTGAGACCCAAATGTAGTAGGTTCCCTGTCCCCTGCTCAAGAGACAGAGCCAAGTCTCCTCCCCCTGCCTTGGACCACACAGAGGAGCACAAGGAGGCTTTGTGCTTGGTGCGAGATCCCTGCATTCTAGTCGTCCTTGTCAGGGTCCACCCAGGAGCCACATTGATGACGTTATGTGGAATGTACATGTGTGCCCATTACGCAAAAGCTGTGTGGGGTGGGGCCCAGCAGAGGAGATGCTCAGAGACTGGATGCCCCGCTGAACAGGCAGAGCAGGGCCCTTCACCCAGAGATATGCCCTGACCTGAGAGAGCAGAAAGTGGCCAGCCTGGAAGTGTGGTGGAACCTCCCAGGAGCGGGAGCAGCTGCTGGGGAAGCGTGTGTGGCAGGAGGAGGTGGAACCCTGTCTCCTCCGTGGGTGTGGGTGTGTGTTGTGGACACAG
Seq C2 exon
ACTGCAGGGTCGAGGCTCACCCCTGTGAGCACAGGACGCTGGAGATGGTCCGGGAGTTCGCTGGCAATGCCCCATGCTGGAGAGGATCGCGGCGGACCCTTGCGGTGCTGGCTGCACACTGTCCCTTCTACAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000165816-VWA2:NM_198496:7
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.022 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0009223=VWA=PD(19.2=71.7)
A:
NA
C2:
PF073337=SLR1-BP=PU(6.0=6.7)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GGAGGAGCTGCATGCACTG
R:
GTAGAAGGGACAGTGTGCAGC
Band lengths:
262-933
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)