HsaINT0185993 @ hg19
Intron Retention
Gene
ENSG00000121741 | ZMYM2
Description
zinc finger, MYM-type 2 [Source:HGNC Symbol;Acc:12989]
Coordinates
chr13:20576990-20579379:+
Coord C1 exon
chr13:20576990-20577275
Coord A exon
chr13:20577276-20579213
Coord C2 exon
chr13:20579214-20579379
Length
1938 bp
Sequences
Splice sites
5' ss Seq
AAAGTAAGG
5' ss Score
6.6
3' ss Seq
ATGTACCACTTATTTTTCAGAGA
3' ss Score
8.19
Exon sequences
Seq C1 exon
ATTCTTGGATCTCCCAGTCAGCTTCATTTCCCCGTAATCAGAAACAACCAGGGGTGGACTCTTTATCACCAGTGGCCTCACTTCCTAAACAGATTTTCCAGCCGTCTGTCCAACAGCAGCCTACTAAACCAGTTAAAGTCACTTGTGCAAACTGCAAAAAACCTTTACAGAAGGGCCAGACAGCTTATCAACGAAAAGGATCAGCTCACCTCTTTTGTTCTACCACCTGCCTTTCTTCCTTCTCCCACAAGCCTGCTCCAAAGAAACTCTGTGTTATGTGTAAAAA
Seq A exon
GTAAGGTTTACCTTTCAACATAATTACATATAGTTGAATTTTGGAGTTGTAAAATTTTAAGAAAAGTGAAACAGATTTGTAATACCTTTGGAAACTTCCCTATCAAGTCCAGGTGGCATATGGATAAAAGGCTTCCTGTTTGGATGGCATTGGAGTTGATTTAGATAGGTCCTTATAATTAATTTTGTCTGTAATCTCCATTGGACTCTTTGATTTTGTAACAATACATACTTATTTACATGATTAATGAGAAGAAATTAGTTCTTATAGCCAAATAAAAATGCTAAGCAGTTTATGCGTGATTCTGTGTTAAAATTGGTTAAATTTTACCCTGTCTTCAGATCAAGATTATAAAATTGGCAAGTCTTTGGATTTTATATGTGTTTGTTTTGAACATTAAGTCATTAGAAATAGTATTTCAAGACTCAGGTACCAATTTTTAGCCAGCCTTAGAAAGGCAGGATCCTCTCTTCTACTGTTTTTTTCTTTTTCTTTTTCTTTTCTTTTTTTTTTTTTAGGCAGAGTCTCATTCTGTAGCCCAGGCTGGAGTGCAATGGTGCGATCTCAGCTCACTGCAGCCTCCACCTCCTGGGTCCTCCACCTCCTGGGTTCAAGCAGTTATCCTGCCTCAGCCTCCCGAGTAGTTAGGATTACAGGCTTTCGCCACCATGCCCAGCTAATTTTTGTATTTTTAGTACAGATGAGGTTTCAGCATATTGTCCAGACTGGTCTTCAGCTCCTGACCTCAGGTGATCTGCCCACCTCAGCCTCCCAAAGTGCTGGGATTATAGGCGTGAGCCACCATGCCCAGCCCTCTTCTGCTGTTTTTTGATCTAGCTTCACTGGTTAAAAATAGCTGGAATATGGTATGTTATATGCAAGGTAAAGCCTGGTGGCCTTTCTGTACCATATCTTGGAGCAGCTCAATTCTCCGAAGCTATATTTAGATCTTGAATTTTACAAAGAGCTTAGTGTTCTCTACATGTTTAATAAATTCAAATACTGAAACAATTGTTACACAGATTGCTTTGCAGTAGTAAACTTAAATACTACAGTGTAGGATCTTGAAAATCAGAATAAAAGGAAAACTTCAAAGGTCATCAGTATTGTCAGTTTTGTTTTGTTTTGTTTTTTTTTGAGACGGATTCTCGCTCTGTCGCCCTGGCTGGAGTGCAGTGGCGCTGATCTCCGCTCACTGCAAGCTCCGTCTCCTGGGTTCATGCCGTTCTCCTGCCTCAGCCTCCTGAGTAGCTGGGACTACAGGTGCCTGCCACCATGCCTGGCTAATTTTTTGTGTTTTTAGTAGAGACGGGGTTTCACCATGTTAGCCAGGATGGTCTCGATCTCCTGACCTCGTGATCCACCCGCCTCAGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACTGCGCTCAGCAGTATTGTCATTTTCTAATATTTCTATTTACTGTTGGAGAGCCATGTTAATAGTGGGTGAGGTTATTTGGGGATGGGGTGTGTGGGTATATTTAAGTTCAGTTATCCCTCTAGAACGTATACCATATTCCCCATAACCCAGATACCTCTTACTTTCTACTTATCCAGGGGAGGGAATTGAACAGGTTATACCTCAGTAAATTAATCCTTAACATTAATTCCATATAACTAATAACAGCTTTTCTTTTTTTAGTTTTCCCAATATTTGAAATCCTTTTTAGTGAATTTAAAGATAAATTGAGTAGCGGCAAAGATTTAATAGTATAAAATATTTTTGCTTCTCAAAAGTCTTTATTTCCAAACATATTTTATTAGGAATGTCTAATAAAAATGATTTATTAGATCCAAGAATGATGTTTGATTTGCAGGACTTAGTCTATAGAAATGAAAAATGTCACTTATGACTCTTATATTTGATTTCTTTTAAAATGGAATTTTAATATGTACCACTTATTTTTCAG
Seq C2 exon
AGATATAACTACAATGAAAGGAACCATTGTTGCTCAAGTGGATTCAAGTGAGTCCTTCCAGGAATTCTGTAGTACATCTTGTTTATCTCTCTATGAAGACAAACAGAATCCTACTAAAGGAGCTCTAAATAAATCAAGATGTACAATCTGTGGTAAACTAACTGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000121741-ZMYM2:NM_003453:5
Average complexity
IR-C
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.338 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF064679=zf-FCS=WD(100=42.7),PF064679=zf-FCS=PU(28.9=13.5)
A:
NA
C2:
PF064679=zf-FCS=PD(68.9=55.4),PF064679=zf-FCS=PU(40.0=28.6)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGGATCTCCCAGTCAGCTTCA
R:
CCTGGAAGGACTCACTTGAATCC
Band lengths:
343-2281
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)