HsaINT0186754 @ hg19
Intron Retention
Gene
ENSG00000170265 | ZNF282
Description
zinc finger protein 282 [Source:HGNC Symbol;Acc:13076]
Coordinates
chr7:148903788-148904562:+
Coord C1 exon
chr7:148903788-148903914
Coord A exon
chr7:148903915-148904442
Coord C2 exon
chr7:148904443-148904562
Length
528 bp
Sequences
Splice sites
5' ss Seq
TGGGTAAGG
5' ss Score
9.08
3' ss Seq
TCCCTCCTCCTCACTTCCAGACG
3' ss Score
10.13
Exon sequences
Seq C1 exon
GTTCCAGTGACTTTTGTCGACATTGCTGTGTACTTCTCCGAAGACGAGTGGAAGAACTTGGACGAATGGCAGAAGGAGCTTTATAACAACCTTGTTAAGGAGAACTACAAAACCCTCATGTCCCTGG
Seq A exon
GTAAGGACACCTTCTCTCCTCTTTGGTGAGCCATCTCTGCAGAGGGTTGTGAAATGCTTATTTGTCCACGTTAGCACCGCCTAGGCAGGTTGTTTCATATTTTTATGTAATGGAAACTCAGGAAACCATTTGCTTATAATGCTAGTAGGATAGAACAGTTTACAATAGGATAAAAATTTAAAACCCAGTAACAGGGCCCATTACCATAGAACTCAACGTTACACCACTACCACGTTGGATTACAGTAAAACAGCACCATTCGCACCTCACCACGCACCACATCCCAGCAGCCCGCGGTAAGCCATAGCTGGTCTGATGTTGGCTTTCAGAGACCAGCTCTTCCTACAGTAGAAATTTGGGCATCTATCGACTCGTTTTCAGATTACCCGCCTAACTCGCATAACTGCTGCCAAAGAGGGACACCCAGGAGGAGAGGGGGAGATGGGGTAGGGGAGAGTTCTCCCTTCCCCTTGCTGGATGCGTTGGTCAACTTCACTCAGCCTTTCCCTCCCTCCTCCTCACTTCCAG
Seq C2 exon
ACGCGGAGGGCTCAGTCCCCAAGCCAGATGCTCCAGTCCAGGCTGAGCCCAGGGAAGAACCTTGTGTGTGGGAGCAGCGCCACCCCGAAGAGAGAGAAATCCCAATGGATCCCGAAGCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000170265-ZNF282:NM_003575:3
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.041 A=NA C2=0.982
Domain overlap (PFAM):
C1:
PF0135222=KRAB=WD(100=95.3)
A:
NA
C2:
PF0135222=KRAB=PD(0.1=0.0)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ACTTTTGTCGACATTGCTGTGT
R:
CTGCTTCGGGATCCATTGGG
Band lengths:
238-766
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)