HsaINT0187281 @ hg19
Intron Retention
Gene
ENSG00000185219 | ZNF445
Description
zinc finger protein 445 [Source:HGNC Symbol;Acc:21018]
Coordinates
chr3:44491939-44492454:-
Coord C1 exon
chr3:44492360-44492454
Coord A exon
chr3:44492066-44492359
Coord C2 exon
chr3:44491939-44492065
Length
294 bp
Sequences
Splice sites
5' ss Seq
CAGGTGAGC
5' ss Score
9.6
3' ss Seq
AGGGCACAGTGTTTTTTCAGGAG
3' ss Score
1.85
Exon sequences
Seq C1 exon
ATACTCCTGCTGCCCAGATGCCTGCCCTTTTCCCGAGAGAGGGGTGCCCGGGAGACCAGGTAACACCAACCAGGTCCCTGACAGCCCAGCTCCAG
Seq A exon
GTGAGCCACAGAACATTTGGTCCTTCCTGATGTCCCCACGTCGCTGCCTAATGGGATAGTGCAGCTTCCCCATCCTGGGTTTCTCTGTCTAGTAATCTCACATCCAAAGACCCGTGTTCCAGAGACCAGATTATCCCCCTCAAGCCCAGAGGTCTTCTGCTGGGTGATGGTCTTCCCTTTCACCTTTGCCAGGTCCATCCTGCACTCACACAGAGCCAGTTTATTCCCCTTCTCTCCCTTTCCACCTCAAAGCTGGGAGCTGTGGACCAGCTCTAGGGCACAGTGTTTTTTCAG
Seq C2 exon
GAGACCATGACTTTCAAGGATGTGGAGGTGACCTTCTCCCAGGACGAGTGGGGGTGGCTGGACTCTGCTCAGAGGAACCTGTACAGGGATGTGATGCTGGAGAATTATAGGAACATGGCTTCCCTGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000185219-ZNF445:NM_181489:5
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.850 A=NA C2=0.045
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
PF0135222=KRAB=WD(100=95.3)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ATACTCCTGCTGCCCAGATGC
R:
CCAGGGAAGCCATGTTCCTAT
Band lengths:
222-516
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)