HsaINT1011342 @ hg38
Intron Retention
Gene
ENSG00000105877 | DNAH11
Description
dynein axonemal heavy chain 11 [Source:HGNC Symbol;Acc:HGNC:2942]
Coordinates
chr7:21744438-21745063:+
Coord C1 exon
chr7:21744438-21744599
Coord A exon
chr7:21744600-21744869
Coord C2 exon
chr7:21744870-21745063
Length
270 bp
Sequences
Splice sites
5' ss Seq
GAAGTAAGC
5' ss Score
6.95
3' ss Seq
TTCTCTTTCTCATCCTGCAGGGT
3' ss Score
11.97
Exon sequences
Seq C1 exon
GGGATTTTATTTGCTTCTCCTGAGTGTTTAAAAGGTCCACTTGATTTAATACATCTGTGGCTTCATGAATCTGCCCGTGTTTATGGAGACAAACTGATAGACAAAAAAGATTGTGATTTGTTTCAGAGAAGAATGCTGGAAACTGCTTATAAATATTTTGAA
Seq A exon
GTAAGCGTATGAATGTCAGAGGTCACTACTTACTCCAACACCAACTGGGTATTGGGACTAAAGTTAGATGAGGGTATGAGAGAAGTGCACAAGGGCTTACCTTTTTGCAATGGCTGTGAATCCAGAATACACTTGGTCTATGCTTGGGAACATTCCACCCACCTACCCATGTGTGGGTCTGCAAGCTTTTCCCTTGCTAGGCCATGCTGCCTGCAGCTGGACCTCTATGGATGGTTGACATGCCATATTTTTCTCTTTCTCATCCTGCAG
Seq C2 exon
GGTATAGATAGTCACATGCTGCTTCAACAGCCCCTCATTTATTGCCACTTTGCTGATAGAGGGAAGGACCCACATTACATGCCAGTGAAGGACTGGGAAGTGCTGAAGACGATTCTTACAGAAACGTTAGACAACTACAATGAACTAAATGCTGCCATGCACCTAGTTTTGTTTGAAGATGCCATGCAACATGT
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000105877:ENST00000409508:50
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF127752=AAA_7=PD(8.1=40.7)
A:
NA
C2:
PF127802=AAA_8=PU(7.1=29.2)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Conservation
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGTGGCTTCATGAATCTGCCC
R:
ACATGTTGCATGGCATCTTCA
Band lengths:
301-571
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains