HsaINT1024318 @ hg38
Intron Retention
Gene
ENSG00000169994 | MYO7B
Description
myosin VIIB [Source:HGNC Symbol;Acc:HGNC:7607]
Coordinates
chr2:127607206-127608878:+
Coord C1 exon
chr2:127607206-127607424
Coord A exon
chr2:127607425-127608707
Coord C2 exon
chr2:127608708-127608878
Length
1283 bp
Sequences
Splice sites
5' ss Seq
AATGTAGGT
5' ss Score
5.12
3' ss Seq
TTCCTCCACGGGGTATGCAGGCG
3' ss Score
2.57
Exon sequences
Seq C1 exon
ATCCTCGTGGGCTTTGAGCGCCTGCAGGCTATTGCCCGGAGCCAGCCGCTGGCGAGGCAGTACCAGGCCATGCGGCAGAGGACAGTCCAGCTGCAGGCCCTGTGCAGGGGATACCTGGTGCGCCAGCAAGTCCAGGCCAAGAGGAGGGCAGTGGTGGTCATTCAGGCCCATGCCAGGGGCATGGCTGCCCGGCGCAACTTCCAGCAAAGGAAGGCCAAT
Seq A exon
GTAGGTGGTCACCTGGCCTCTTGGGCAGGTGGGGCTGGCTGGGGCCCCAGTGGGTGAGGGCAAGAAGGAGTGAGCGGCTGTGTAGAGAGCTCACCAGAAGCGCTTTGGAAAATCCCCCCGCCCCCGCCACAAGCCAAGACGTTAAAATCTGTTCAATTACTCAAGAGCACAGCAAGGATACAGGACACAAGATGCAAATTAGCAGGCACCTGGGCTGAGATGTAGCTATCACGAGAGACACACCGTCCTCCTCTCCCTATTCAAAGTCAGTTCTACAATGGCTCTGCAATGGCTGGGGAGCCGTGGCCACCACCCAGGAGCACGCAGGGTATAGCATGGGAGAGGCAGCAGGTCAATGGGACAGCCTTAGCCTTGAACCTGGAAGGTGAGCTCAGGTCCCCTCCCTTTCACCTTGGAGATGATTTCTGGGGCAGGGATGGTTGGTCCCCTGGAAGGTGCAGCAAAGCTGAGCCAGACAAGCTGGGAAAGGCCCCAGTTCCATGGAAGAGAGCAAAGTGTCCTGGTTACTGGGCTGTGTATGACAGCTCAGGGGACAGAGAAATATTAATACCAAGGGGAGCTGCTGAGTGTCTGGGGGGCTGGGAGGACACTGAGCAGGGGGACAGCACCAAGAAAATAACCCCATTTCCTCCATCGAGTACTCGAGACTCAACCTTCACACTTGGCTCATTTGGAAGTTGTGATAAGGCAAAGGGGCTAGGATGACGTTGACTTCTGCTCCATGGATGAAAACTTGGTCTACTAAGCACACTGCTAATACAGTGAACAGGGCAAATGAGAGAATGCACCCATAGACACGTCAGCAGCATGCTTCTGCACCCGCATGCCCCCAGCTGCCTGCAAAGCAGCCTTATCTGTGACTTCGTTACTGCAGCCCCTGGGGACCTGTCCTGGTGGACCCTTTTTGCCCTTTGAATAAAGGGACCAAGTGGTCCTGAGCAGTGGTTGTGCAGCTGGGTTCCTGGGGGTCCCTGGAGTTTGAAGGGGTGCCTTAAGAGCCATCTGAGGGTAGGGACAAGCCAGCAACCTCACCTCTCCAGAGCTCTGATTATCACTGGGAAAGGGAAAGCCCTGGCTGGTTGATCTCTAACCACACTAGCTGTTAAAATCTACTGTTTCAGAGCAGAATATTGATTTGGACAAATGATGGCAGGATGAGGCTTACTTGGCTTCTGGGAGGTGCTTGCCCTGTGGGGTAGGCAGGGCTGGGCCCCCTGAGCCCTGCTGGGCCCCTGGGTAACCTTCCTCCACGGGGTATGCAG
Seq C2 exon
GCGCCGCTGGTCATCCCGGCCGAGGGGCAGAAAAGCCAAGGCGCTCTCCCTGCCAAGAAGCGCAGATCCATCTACGACACCGTCACTGACACGGAGATGGTGGAGAAGGTGTTCGGCTTCCTCCCTGCCATGATTGGGGGCCAGGAGGGCCAGGCCTCGCCGCACTTTGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000169994:ENST00000409816:20
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.014 A=NA C2=0.193
Domain overlap (PFAM):
C1:
PF0061222=IQ=WD(100=28.8)
A:
NA
C2:
NO
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ATCCTCGTGGGCTTTGAGCG
R:
CCAATCATGGCAGGGAGGAAG
Band lengths:
356-1639
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains