HsaINT1028236 @ hg38
Intron Retention
Gene
ENSG00000261603 | PRSS46
Description
protease, serine 46 [Source:HGNC Symbol;Acc:HGNC:37325]
Coordinates
chr3:46734065-46736429:-
Coord C1 exon
chr3:46736307-46736429
Coord A exon
chr3:46734243-46736306
Coord C2 exon
chr3:46734065-46734242
Length
2064 bp
Sequences
Splice sites
5' ss Seq
AAGGTAAGG
5' ss Score
10.51
3' ss Seq
CTGAGATCCTCTTTCCTCAGGGC
3' ss Score
7.54
Exon sequences
Seq C1 exon
ATCCGTTAGAAGGAGCATTGAGGAGTAGATACCCACTTGCCATGGCCTGTGGGCCGGGGGATCTTCAAAGCCTTACATCTCCGCTTTCCTCTGCCAGATTAGATTATCAGCCGTCTATTGAAG
Seq A exon
GTAAGGCTTCAGGGGCATGGGACGGAGGCTGGAGGGGTCTGTTTGCCGGGTGCCTGTGTCGGGCTGTCCTCATGCCTGAAGGGCCTTGGTGTGTCCATGTCCTGGTGGGTGGTACATCCTCAGCAGACTGGGGACCCAAACGGTGTCAGGGCGGTTCCAATTTCAAGGGTGACCATGACAGGAGGGAAGAGCCTTATTAAAAATGGGGGAACGCAGTGGGCACAGTGGCTCACGCCTGTAATCCCAGCACCGTGGGAGGCCAAGGAGGGCGGATCACTTGAGACTAGCCTGGCCAACATGGCAAAACCCTGTCTCTACTAAAAATACAAAAATTGGGCATGGTGGTGCACATCTGTAATCCCAGCTACTCAGGAGGTTGAGGCACGAAAACAGCTTGAACCTGGGAAGTGGAAGTTGCAGTGAGCTGAGATCACACCACCGCACACCAGCCTGGGTGACAAAGTGAGACTCCATCTCAAAAAAAAAAAAAAAAAAAAGGAACAGACTAACACTAACACTAACACTAACATCCATGGAACGAGTGAGCTTGTTTGGGAGGCACAGTCATAGGAGACCCCATCTTGCGATGATGAGGAAGTGAGGCTTAGTGCCCACTCTGTATCAGCGCGGCTGAGACTGAGTGAGGTCGCAACACCCTGTGAGGCGAGCTTCACCAGCATCCCATTTCACAGTGAGAAACTGAGACTCACAGAGCTTCAGTGGTTTGCGAGTGCTGTAGCCAGAATTCAATACCTGTGTTCAATAGACTCTTTGGGGGTGAAAAAAGGATGACATGCAAATTCGTGAAGCGTTCCATATTTAAAAAAAAAAGATTAAAATTTTTTTAGAGACAGGGTCTTGCTCTGTCACCCAGGCTGGAATGGAGGGTGCAATCCTAGTTCACTGTAGCCTTGAACTCCTGGGCTCAAGTGATCCTCCCGCCTCAGTCTCCTGAGTAGCTGGGACTACAGGTGTGCACCACCACACCTGATTAATTTTGCTTTTGTAGAAATAAGATCTCGCTATGTTGCTCAGGCTGGCCTTGAACTCCTGGCCTCAAGCCATCCTCCCTCCTGGGCTTTCCAAAGCTCTGTGATTACTGGTGTGACTTTCTCCCTTTCTTATCCTTTATGATGTTTAGTTAGTAAATACCTGTAGCAATCCAGACTGGGCCTGTTTAAAATCTCCATCTCACACCTGGTTCAGTGCAGCCTGCTCTCTTCTCACCCCTGCTGCTGGGGCCAGTGAGAGTCAAGGAGGGAATGGACACACATCTCTACTCACTTCCCTACACGGTCACAAGGACTGCACCTCCAGGGGCATGGGTGGCCCCTAGAGCAGTGCAGTGTGACATTACTCTTCACTGGGGACAGGCAGCCTGGCCGACTTGTGCCCCATCACCTATCCCCTGGCTGACAGCTCGCCCCTGTGGTGATTCTCTCTTCTGCTTCTCTCCCCCAACCATCTGTTTGTGTAAACTACGGGCAAGGATGAGTCCTGGGTGATGGCTTACAACAAGCCCAGGAGGAGTTGTCTGGTCCTCATTGTTTGGGAACTCTAGAATGTGGGGTACCTGCTGACCCTGGCCTTTGGTTGCCTTTTTTTTTTTTTTTTTTTTTTTTTGAGATAGAGTCTGGCTCCGTCGCCCAGCCTGGAGTGCTGTGGCACGATCTCGGCTCACTGCAACCTCCACCTCCCAGGTTCAAGCGATTCTCCTGCCTCAGCCTCCTGAGCAGCTGGGATTACAGGCACGTGCCACCACGCCAGGCTAATTTTTGTATTTTTAGTAGAGATGGGGTTTCATCATATTGGCCATGCAGGTCTTGAACTCCTGACCTCAAGCGATCCCCCCACCTTGGCCTCCCAAAGTGCTGCAATTATAGGTGTGAGCCACTGCGCCCGGCTGGTTGCCAGTTTTGAGGCAGTGGGAAAAGCCCCTTCTCACATGTGCATGTGGCAGTGGCTGCTTATGACAGGGCTGGAAGGCAGCTCTCTCTGTCTCAAATCTGCTGTGTCCAGGGGTGTGAGGGTTGCCCTTTGCTGCCTGAGATCCTCTTTCCTCAG
Seq C2 exon
GGCCCTGGCTCCGGGCCTGCGGTCAGACCAACGTGTCCTGCAGGGTGGTGAAGGGGAAGCTGGTAGAGGTAGGCAAGTGGCCATGGCAGGTGAGCATCCTTTTCCTGGGCACGTACATCTGCAGTGGCTCCCTCATCCACCACCAGTGGGTCCTCACGGCTGCGCACTGCTTGCAGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000261603:ENST00000463091:1
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion (1st CDS intron)
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
PF0008921=Trypsin=PU(33.3=73.3)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains