MmuEX0002991 @ mm10
Exon Skipping
Gene
ENSMUSG00000028125 | Abca4
Description
ATP-binding cassette, sub-family A (ABC1), member 4 [Source:MGI Symbol;Acc:MGI:109424]
Coordinates
chr3:122156338-122158443:+
Coord C1 exon
chr3:122156338-122156485
Coord A exon
chr3:122157835-122157958
Coord C2 exon
chr3:122158314-122158443
Length
124 bp
Sequences
Splice sites
3' ss Seq
GCCTCACTTCTCTTTCTCAGACG
3' ss Score
8.48
5' ss Seq
TTGGTGGGT
5' ss Score
4.3
Exon sequences
Seq C1 exon
ATGGGCAGTCATTCCTATGATGTATCCAGCATCCTTCCTGTTTGAAGTCCCCAGCACAGCCTATGTGGCTTTGTCCTGTGCTAACCTGTTCATCGGCATCAACAGCAGCGCCATCACCTTCGTCCTGGAATTATTTGAGAATAACCGG
Seq A exon
ACGCTGCTCAGGTTCAATGCCATGTTGAGGAAGTTGCTCATTGTCTTCCCCCACTTCTGCCTGGGCAGGGGCCTCATTGACCTGGCACTGAGCCAAGCTGTGACAGACGTCTATGCCCAGTTTG
Seq C2 exon
GTGAGGAGTACTCTGCAAACCCATTCCAGTGGGACCTGATTGGGAAGAACCTGGTTGCTATGGCAATAGAAGGGGTGGTATACTTCCTTCTGACCCTGCTCATCCAACACCATTTTTTCCTCACCCGGTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000028125_CASSETTE5
Average complexity
S*
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF126982=ABC2_membrane_3=FE(16.3=100)
A:
PF126982=ABC2_membrane_3=FE(13.7=100)
C2:
PF126982=ABC2_membrane_3=PD(11.0=75.0)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGGGCAGTCATTCCTATGATGT
R:
GTGTTGGATGAGCAGGGTCAG
Band lengths:
257-381
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Pre-implantation embryo development
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types