MmuEX0003624 @ mm10
Exon Skipping
Gene
ENSMUSG00000015143 | Actn1
Description
actinin, alpha 1 [Source:MGI Symbol;Acc:MGI:2137706]
Coordinates
chr12:80168858-80171875:-
Coord C1 exon
chr12:80171729-80171875
Coord A exon
chr12:80170183-80170248
Coord C2 exon
chr12:80168858-80169016
Length
66 bp
Sequences
Splice sites
3' ss Seq
TTGGCGCCACTGCCCTACAGAAG
3' ss Score
4.29
5' ss Seq
ATGGTAACG
5' ss Score
6.05
Exon sequences
Seq C1 exon
CATATCCGTGTGGGCTGGGAGCAGCTGCTCACCACCATTGCCAGGACCATCAATGAAGTGGAGAACCAGATCTTGACCCGGGATGCCAAAGGCATCAGCCAGGAACAGATGAACGAATTCCGCGCCTCTTTCAACCACTTTGACCGG
Seq A exon
AAGAAGACGGGCATGATGGACACAGACGATTTCCGCGCCTGCCTTATCTCCATGGGTTACAACATG
Seq C2 exon
GGAGAGGCAGAGTTTGCCCGAATCATGAGCATTGTAGACCCCAACCGCTTGGGGGTAGTGACGTTCCAGGCCTTCATCGACTTTATGTCCCGAGAGACGGCAGATACTGATACTGCAGATCAGGTCATGGCTTCCTTCAAGATCCTGGCTGGAGATAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000015143_MULTIEX1-2/2=C1-C2
Average complexity
ME(1-2[97=100])
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (No Ref)
No structure available
Features
Disorder rate (disopred):
C1=0.000 A=0.000 C2=0.057
Domain overlap (PFAM):
C1:
PF0043516=Spectrin=PD(20.2=42.9),PF134991=EF-hand_7=PU(31.3=53.1)
A:
PF138331=EF-hand_8=PU(37.7=90.9)
C2:
PF134991=EF-hand_7=PD(33.7=52.8),PF087265=EFhand_Ca_insen=PU(26.9=34.0)
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GCGCCTCTTTCAACCACTTTG
R:
GCCAGGATCTTGAAGGAAGCC
Band lengths:
175-241
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Pre-implantation embryo development
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types