Special

MmuEX0004931 @ mm9

Exon Skipping

Gene
ENSMUSG00000069601 | Ank3
Description
ankyrin 3, epithelial [Source:MGI Symbol;Acc:MGI:88026]
Coordinates
chr10:69443020-69444945:+
Coord C1 exon
chr10:69443020-69443142
Coord A exon
chr10:69443572-69443598
Coord C2 exon
chr10:69444864-69444945
Length
27 bp
Sequences
Splice sites
3' ss Seq
ATGCATCTTGGGACCAAAAGGAG
3' ss Score
-1.15
5' ss Seq
GAGGTAATA
5' ss Score
7.96
Exon sequences
Seq C1 exon
ATCAGAGACACCAGTCAAGAGCCCTGTGGCCGCCTGTCTTTCCTGAAGGAGCCAAAGACAACAAAGGGATTACCCCAAACAGCTGTTTGCAACTTAAATATTACTCTGCCGGCACATAAAAAG
Seq A exon
GAGACAGAGTCAGATCAAGATGATGAG
Seq C2 exon
GCTGAGAAGGCAGACAGACGCCAGAGCTTTGCCTCCCTAGCTTTACGTAAGCGCTACAGCTACTTGACTGAACCCAGCATGA
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000069601_MULTIEX2-1/4=C1-2
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact





	

	
Alternative protein isoforms (No Ref)





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.052 A=1.000 C2=0.083
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
NO

							
A:
NO

							
C2:
NO

						

					

				








    
Main Inclusion Isoform:
ENSMUSP00000090090f5392A





     
                   









    
Main Skipping Isoform:
ENSMUSP00000090090f5603A





     
      









    
Other Inclusion Isoforms:
NA
          









    
Other Skipping Isoforms:
ENSMUSP00000045834, ENSMUSP00000061698, ENSMUSP00000090087, ENSMUSP00000090088, ENSMUSP00000090089, ENSMUSP00000090090, ENSMUSP00000090090f5390A, ENSMUSP00000090090f5391A, ENSMUSP00000090090f5393A, ENSMUSP00000090090f5394A, ENSMUSP00000090090f6290A, ENSMUSP00000090090f6291A
  



Associated events






Other assemblies


mm10




Conservation


Human
(hg38)
chr10:60082150-60082176 
ALTERNATIVE
HsaEX0004157
(ANK3)
Human
(hg19)
chr10:61841908-61841934 
ALTERNATIVE
HsaEX0004157
(ANK3)
Rat
(rn6)
chr20:20430354-20430380 
ALTERNATIVE
RnoEX0009385
(Ank3)
Cow
(bosTau6)
chr28:15877946-15877972 
ALTERNATIVE
BtaEX0003420
(ANK3)
Chicken
(galGal4)
chr6:8479698-8479724 
ALTERNATIVE
GgaEX0004067
(chAnk3)
Chicken
(galGal3)
chr6:10140609-10140635 
ALTERNATIVE
GgaEX0004067
(Q90717_CHICK)
Zebrafish
(danRer10)
chr12:7633804-7633830 
ALTERNATIVE
DreEX0013144
(ank3b)
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
GCCTGTCTTTCCTGAAGGAGC

				
R: 
CAAAGCTCTGGCGTCTGTCTG

				
Band lengths: 
123-150

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Pre-implantation embryo development
  • Neural differentiation time course
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types






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