Special

MmuEX0006431 @ mm10

Exon Skipping

Description
argininosuccinate lyase [Source:MGI Symbol;Acc:MGI:88084]
Coordinates
chr5:130013963-130016174:-
Coord C1 exon
chr5:130016097-130016174
Coord A exon
chr5:130014679-130014731
Coord C2 exon
chr5:130013963-130014025
Length
53 bp
Sequences
Splice sites
3' ss Seq
TGAACCCCGTCTCTCTACAGTGG
3' ss Score
8.52
5' ss Seq
CAGGTGAGG
5' ss Score
10.07
Exon sequences
Seq C1 exon
CCACGCTGTTGCGCTGACACGAGATTCAGAGAGACTCTTGGAGGTGCAGAAGCGGATCAATGTCTTGCCACTGGGGAG
Seq A exon
TGGGGCCATTGCAGGCAACCCTCTGGGTGTGGACCGGGAGCTACTCCGTGCAG
Seq C2 exon
AACTGAACTTTGGGGCCATCACTCTCAACAGCATGGATGCCACCAGTGAGAGAGACTTTGTGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000025533-'19-28,'19-26,21-28
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact

ORF disruption upon sequence exclusion

No structure available
Features
Disorder rate (Iupred):
  C1=0.000 A=0.003 C2=0.000
Domain overlap (PFAM):

C1:
PF0020615=Lyase_1=FE(10.3=100)
A:
PF0020615=Lyase_1=FE(6.1=100)
C2:
PF0020615=Lyase_1=FE(19.4=100)


Main Inclusion Isoform:


Main Skipping Isoform:
NA


Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal4)
HIGH PSI
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
HIGH PSI
(asl)
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGTTGCGCTGACACGAGATTC
R:
CAAAGTCTCTCTCACTGGTGGC
Band lengths:
132-185
Functional annotations
There are 0 annotated functions for this event


GENOMIC CONTEXT[edit]

INCLUSION PATTERN[edit]


SPECIAL DATASETS

  • Pre-implantation embryo development
  • Ribosome-engaged transcriptomes of neuronal types
  • Neural differentiation time course
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types