MmuEX0011383 @ mm10
Exon Skipping
Gene
ENSMUSG00000041189 | Chrnb1
Description
cholinergic receptor, nicotinic, beta polypeptide 1 (muscle) [Source:MGI Symbol;Acc:MGI:87890]
Coordinates
chr11:69794969-69795943:-
Coord C1 exon
chr11:69795822-69795943
Coord A exon
chr11:69795595-69795734
Coord C2 exon
chr11:69794969-69795013
Length
140 bp
Sequences
Splice sites
3' ss Seq
TTAGTGCTTTCCTTCGTCAGGCG
3' ss Score
5.37
5' ss Seq
CTGGTGAGA
5' ss Score
7.54
Exon sequences
Seq C1 exon
CGTCACTTCCCCTGGCCTGAGGCCGCTATCCGGACAAACTTCACTGAGCGAAAGAGGCAGGGCCATGGCCTTAGGGGCGCTGCTTCTGCTTCTAGGGGTACTCGGGACGCCCCTCGCCCCAG
Seq A exon
GCGCCCGCGGGTCGGAAGCCGAAGGCCAACTGATTAAGAAACTTTTCTCCAACTATGATAGCTCGGTGAGGCCGGCGCGGGAGGTGGGAGACCGCGTCGGGGTCAGCATCGGCCTCACCCTGGCGCAACTCATCAGCCTG
Seq C2 exon
AACGAGAAGGATGAAGAAATGAGCACAAAGGTGTACTTAGACCTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000041189-'0-3,'0-1,3-3
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
NO
A:
PF0293118=Neur_chan_LBD=PU(17.8=83.0)
C2:
PF0293118=Neur_chan_LBD=FE(6.4=100)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TCACTTCCCCTGGCCTGAG
R:
GGTCTAAGTACACCTTTGTGCTCA
Band lengths:
163-303
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Pre-implantation embryo development
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types