MmuEX0015767 @ mm9
Exon Skipping
Gene
ENSMUSG00000026131 | Dst
Description
dystonin [Source:MGI Symbol;Acc:MGI:104627]
Coordinates
chr1:34348632-34351391:+
Coord C1 exon
chr1:34348632-34348761
Coord A exon
chr1:34350165-34350328
Coord C2 exon
chr1:34351229-34351391
Length
164 bp
Sequences
Splice sites
3' ss Seq
CTGAAGTTGTGTTTTACCAGGGA
3' ss Score
5.21
5' ss Seq
GAGGTCAGA
5' ss Score
5.24
Exon sequences
Seq C1 exon
ACCTTCATGGAAGAAATGACCAGAAAACAGCCCGACGTTGATAAAGTTACCAAGACCTATAAGAGGAGGGCCACTGACCCTCCCTCGTTACAGTCTCACATCCCCGTCTTGGACAAGGGACGAGCCGGAA
Seq A exon
GGAAACGCTTCCCAGCCTCGGGCTTCTATCCATCTGGCTCACAGACGCAAATCGAGACCAAGAACCCCAGGGTTAACCTGCTGGTGAGCAAGTGGCAGCAGGTCTGGCTCCTGGCCTTGGAAAGGAGGAGGAAGCTCAACGACGCCCTGGACAGGCTGGAGGAG
Seq C2 exon
CTGAGGGAATTTGCCAACTTCGATTTCGACATCTGGCGGAAAAAATACATGAGGTGGATGAACCATAAGAAATCGAGAGTGATGGATTTCTTCCGGAGAATTGATAAGGACCAGGATGGGAAGATCACTCGACAGGAATTCATCGACGGGATTCTCTCCTCCA
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000026131-'130-129,'130-128,131-129=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.500 A=0.145 C2=0.000
Domain overlap (PFAM):
C1:
PF0043516=Spectrin=PD(44.2=77.3)
A:
NO
C2:
PF134991=EF-hand_7=PU(56.0=76.4)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ATGACCAGAAAACAGCCCGAC
R:
TCCTGTCGAGTGATCTTCCCA
Band lengths:
252-416
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Pre-implantation embryo development
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types
Other AS DBs: