Special

MmuEX0019438 @ mm9

Exon Skipping

Gene
ENSMUSG00000075415 | Fnbp1
Description
formin binding protein 1 [Source:MGI Symbol;Acc:MGI:109606]
Coordinates
chr2:30939543-30960877:-
Coord C1 exon
chr2:30960762-30960877
Coord A exon
chr2:30951547-30951694
Coord C2 exon
chr2:30939543-30939605
Length
148 bp
Sequences
Splice sites
3' ss Seq
CCGGTGCAATCTGTCCTCAGGTA
3' ss Score
10.3
5' ss Seq
TCGGTAATG
5' ss Score
6.42
Exon sequences
Seq C1 exon
GATCAGTTTGACAACTTGGAAAAACATACACAGTGGGGAATCGATATTCTTGAGAAATACATCAAGTTTGTCAAGGAGAGGACGGAGATTGAGCTCAGCTATGCCAAGCAACTCAG
Seq A exon
GTACACGGCTTGCAAAGCCTTTCTTTCCACCCTGAATGAGATGAATGACTACGCCGGGCAGCACGAGGTCATCTCTGAGAACATGACGTCACAGATCACGGTGGACCTGATGCGCTACGTTCAGGAGCTGAAGCAGGAGAGGAAATCG
Seq C2 exon
AACTTCCATGATGGACGGAAGGCTCAGCAGCACATAGAAACGTGTTGGAAGCAACTGGAGTCA
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000075415_MULTIEX1-2/10=C1-3
Average complexity
C2
Mappability confidence:
100%=100=100%
Protein Impact





	

	
ORF disruption upon sequence exclusion





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.000 A=0.101 C2=0.251
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
PF0061118=FCH=FE(40.4=100),PF0319410=LUC7=FE(27.0=100),PF093206=DUF1977=PU(55.1=97.4)

							
A:
PF0061118=FCH=PD(29.8=56.0),PF0319410=LUC7=FE(34.8=100),PF093206=DUF1977=PD(15.9=22.0),PF102754=Peptidase_C65=FE(47.1=100)

							
C2:
PF104814=CENP-F_N=FE(14.4=100)

						

					

				








    
Main Inclusion Isoform:
ENSMUSP00000109194





     
                   









    
Main Skipping Isoform:
NA





     
      









    
Other Inclusion Isoforms:
ENSMUSP00000074796, ENSMUSP00000097781, ENSMUSP00000097782, ENSMUSP00000109181, ENSMUSP00000109184, ENSMUSP00000109184f5508A, ENSMUSP00000109188, ENSMUSP00000109189, ENSMUSP00000109190, ENSMUSP00000109192, ENSMUSP00000115013, ENSMUSP00000120580, ENSMUSP00000121282
          









    
Other Skipping Isoforms:
NA
  



Associated events






Other assemblies


mm10




Conservation


Human
(hg38)
chr9:129978465-129978612 
HIGH PSI
HsaEX6063443
(FNBP1)
Human
(hg19)
chr9:132740744-132740891 
HIGH PSI
HsaEX6063443
(FNBP1)
Rat
(rn6)
chr3:10752368-10752515 
Cow
(bosTau6)
chr11:100361051-100361198 
HIGH PSI
BtaEX6046667
(FNBP1)
Chicken
(galGal4)
chr17:5784965-5785112 
HIGH PSI
GgaEX1025308
(FNBP1)
Chicken
(galGal3)
chr17:6354519-6354666 
Zebrafish
(danRer10)
chr21:6201918-6202065 
HIGH PSI
DreEX6048520
(fnbp1a)
Fruitfly
(dm6)
chr3L:4327773-4327917 
HIGH PSI
DmeEX6014695
(Cip4)




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
GATCAGTTTGACAACTTGGAAAAACA

				
R: 
TTGCTTCCAACACGTTTCTATGTG

				
Band lengths: 
170-318

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Pre-implantation embryo development
  • Neural differentiation time course
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types






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