Special

MmuEX0019439 @ mm9

Exon Skipping

Gene
ENSMUSG00000075415 | Fnbp1
Description
formin binding protein 1 [Source:MGI Symbol;Acc:MGI:109606]
Coordinates
chr2:30914409-30939605:-
Coord C1 exon
chr2:30939543-30939605
Coord A exon
chr2:30938494-30938598
Coord C2 exon
chr2:30914409-30914537
Length
105 bp
Sequences
Splice sites
3' ss Seq
CTTGGCTGTGCTCTCTGCAGAGT
3' ss Score
9.99
5' ss Seq
AAGGTAAGG
5' ss Score
10.51
Exon sequences
Seq C1 exon
AACTTCCATGATGGACGGAAGGCTCAGCAGCACATAGAAACGTGTTGGAAGCAACTGGAGTCA
Seq A exon
AGTAAGAGGAGGTTTGAGCGGGACTGTAAGGAAGCCGACCGGGCACAGCAGTACTTCGAGAAAATGGACGCTGACATCAACGTGACCAAGGCGGATGTGGAAAAG
Seq C2 exon
GCACGACAACAAGCTCAGATACGCCAGCAAATGGCAGAGGACAGCAAAGCAGATTACTCCTTAATCCTGCAGAGATTCAACCAGGAGCAATGGGAATACTACCATACCCACATCCCCAACATCTTCCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000075415_MULTIEX1-4/10=3-5
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact





	

	
Alternative protein isoforms (Ref)





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.251 A=0.132 C2=0.213
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
PF104814=CENP-F_N=FE(14.4=100)

							
A:
PF104814=CENP-F_N=FE(24.0=100)

							
C2:
PF0319410=LUC7=PD(20.6=67.4),PF102754=Peptidase_C65=FE(40.4=100)

						

					

				








    
Main Inclusion Isoform:
ENSMUSP00000109190





     
                   









    
Main Skipping Isoform:
ENSMUSP00000120580





     
      









    
Other Inclusion Isoforms:
ENSMUSP00000074796, ENSMUSP00000097781, ENSMUSP00000097782, ENSMUSP00000109181, ENSMUSP00000109184, ENSMUSP00000109184f5508A, ENSMUSP00000109188, ENSMUSP00000109189, ENSMUSP00000109192, ENSMUSP00000109194, ENSMUSP00000115013, ENSMUSP00000121282
          









    
Other Skipping Isoforms:
NA
  



Associated events






Other assemblies


mm10




Conservation


Human
(hg38)
chr9:129957360-129957462 
ALTERNATIVE
HsaEX0026115
(FNBP1)
Human
(hg19)
chr9:132719639-132719743 
HIGH PSI
HsaEX0026115
(FNBP1)
Rat
(rn6)
chr3:10766061-10766163 
Cow
(bosTau6)
chr11:100344665-100344769 
HIGH PSI
BtaEX6046669
(FNBP1)
Chicken
(galGal4)
chr17:5774746-5774850 
HIGH PSI
GgaEX1025304
(FNBP1)
Chicken
(galGal3)
chr17:6341402-6341506 
HIGH PSI
GgaEX1025304
(FNBP1)
Zebrafish
(danRer10)
chr21:6223953-6224057 
HIGH PSI
DreEX0033188
(fnbp1b)
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
TCCATGATGGACGGAAGGCTC

				
R: 
GGAAGATGTTGGGGATGTGGG

				
Band lengths: 
186-291

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Pre-implantation embryo development
  • Neural differentiation time course
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types






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