Special

MmuEX0023019 @ mm9

Exon Skipping

Gene
ENSMUSG00000055632 | Hmcn2
Description
hemicentin 2 [Source:MGI Symbol;Acc:MGI:2677838]
Coordinates
chr2:31311012-31316258:+
Coord C1 exon
chr2:31311012-31311146
Coord A exon
chr2:31312580-31312708
Coord C2 exon
chr2:31315570-31316258
Length
129 bp
Sequences
Splice sites
3' ss Seq
CCACACCGCTGCCTCCCCAGATG
3' ss Score
7.52
5' ss Seq
TAGGTAAAG
5' ss Score
6.93
Exon sequences
Seq C1 exon
ATGTGGATGAGTGTGCGGGCAACACCCACCTCTGCCAGGAGGAACAGCGCTGTGTGAACCTGCTTGGATCCTATAACTGCCTCGCTTCCTGTAGACCTGGCTTCCGGGTAACTGCTGACGGAAGCAACTGTGAAG
Seq A exon
ATGTGGATGAATGTCTAGAACAGCTGGATGAGTGTCACTACAATCAACTCTGTGAGAACACTCCAGGTGGCCACCACTGTGGTTGTCCCAGAGGGTACCGCCAACAGGGTCACAGCCTGCCTTGCCTAG
Seq C2 exon
GACCTGCTTCCGCCGCTGCTCTCAGGACTGCAGCGCCAGCGGCCCGTCTACACTGCAGTACCGCCTGCTGCCGCTGCCCCTCGGCGTGCGCGCCCACCACGACGTGGCCCGCCTGGCCGCCTTCTCCGAGGCTGGCATCCCTGCCAACCGCACGGAGCTCACCGTGCTGGAGCCCGACCCACGCAGCCCCTTCGCTCTCCGCCAGCTACGCGCTGGACAAGGCGCGGTCTACACCCGCAGAGCGCTCACCCGCGCCGGGCTCTACCGCTTGACTGTGCGCGCAGCGGCACCCCGCCACCAGAGCGTCTACATCCTGCTAATCGCAGTGTCGCCTTACCCGTACTGAGGCCAGAGCTGCAGATCCACCCTGACCTCGCAGAGAGGAACAGAGTGGCCCTTGCCCATGACACCTACAGTGACAGAGAACATCCTCTTCTCCCGCCCCCGTGCGTCAGTGAGATCTTTGGTAAACACTGCTGTGCGCAGAGCCTTGACCCCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000055632_MULTIEX1-2/5=1-C2
Average complexity
C3
Mappability confidence:
100%=100=100%
Protein Impact





	

	
Alternative protein isoforms (Ref)





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.000 A=0.000 C2=0.044
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
PF0764510=EGF_CA=WD(100=95.7),PF0764510=EGF_CA=PU(0.1=0.0)

							
A:
PF0764510=EGF_CA=WD(100=95.5),PF0764510=EGF_CA=PU(0.1=0.0)

							
C2:
NO

						

					

				








    
Main Inclusion Isoform:
ENSMUSP00000109160f4962A





     
                   









    
Main Skipping Isoform:
NA





     
      









    
Other Inclusion Isoforms:
ENSMUSP00000062042, ENSMUSP00000109160
          









    
Other Skipping Isoforms:
NA
  



Associated events







Other assemblies


mm10




Conservation


Human
(hg38)
chr9:130429557-130429685 
HIGH PSI
HsaEX6063477
(HMCN2)
Human
(hg19)
chr9:133304944-133305072 
HIGH PSI
HsaEX6063477
(HMCN2)
Rat
(rn6)
chr3:10388384-10388512 
HIGH PSI
RnoEX6016390
(AABR07072853.4)
Cow
(bosTau6)
chr11:100773113-100773241 
HIGH PSI
BtaEX6046696
(HMCN2)
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
chr8_random:375487-375615 
HIGH PSI
GgaEX6045278
(HMCN1)
Zebrafish
(danRer10)
chr20:34260544-34260672 
HIGH PSI
DreEX6046298
(hmcn1)
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
GCTGACGGAAGCAACTGTGAA

				
R: 
GTGTAGACCGCGCCTTGTC

				
Band lengths: 
256-385

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Pre-implantation embryo development
  • Neural differentiation time course
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types






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