Special

MmuEX0024726 @ mm10

Exon Skipping

Gene
ENSMUSG00000030102 | Itpr1
Description
inositol 1,4,5-trisphosphate receptor 1 [Source:MGI Symbol;Acc:MGI:96623]
Coordinates
chr6:108413769-108416958:+
Coord C1 exon
chr6:108413769-108413953
Coord A exon
chr6:108416177-108416214
Coord C2 exon
chr6:108416810-108416958
Length
38 bp
Sequences
Splice sites
3' ss Seq
TCTGTTTTCCTTTCCTACAGCTG
3' ss Score
12.4
5' ss Seq
AGGGTACAT
5' ss Score
3.77
Exon sequences
Seq C1 exon
CCAAGAGCCGGGCCATAGCCATTCCTGTTGACCTGGACAGCCAAGTCAACAACCTCTTCCTGAAGTCCCACAACATTGTGCAGAAAACAGCCCTGAACTGGCGGTTATCAGCCCGAAACGCCGCTCGCAGAGACTCTGTACTGGCAGCATCCAGAGACTACCGAAATATCATTGAGAGGTTACAG
Seq A exon
CTGTGTGTTTTGCATTTGAAGACCATCATGCTATCAGG
Seq C2 exon
GACATCGTGTCTGCCCTAGAGGACCGGCTCAGGCCCCTGGTGCAGGCTGAGCTGTCTGTGCTCGTGGATGTTCTACACAGACCAGAACTGCTCTTCCCCGAGAACACGGATGCCAGGAGGAAATGTGAGAGTGGAGGTTTCATCTGCAA
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000030102_MULTIEX1-36/59=35-37
Average complexity
S
Mappability confidence:
97%=97=100%
Protein Impact





	

	
In the CDS, with uncertain impact





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.000 A=0.000 C2=0.021
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
NO

							
A:
NO

							
C2:
NO

						

					

				








    
Main Inclusion Isoform:
ENSMUST00000032192fB2082





     
                   









    
Main Skipping Isoform:
ENSMUSP00000032192





     
      









    
Other Inclusion Isoforms:
NA
          









    
Other Skipping Isoforms:
ENSMUSP00000144880
  



Associated events







Other assemblies


mm9




Conservation


Human
(hg38)
chr3:4709692-4709729 
LOW PSI
HsaEX1018097
(ITPR1)
Human
(hg19)
chr3:4751376-4751413 
Rat
(rn6)
chr4:140448764-140448801 
ALTERNATIVE
RnoEX0045414
(Itpr1)
Cow
(bosTau6)
chr22:21747393-21747430 
LOW PSI
BtaEX0018591
(ITPR1)
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
CCCTGAACTGGCGGTTATCAG

				
R: 
TCCTCTAGGGCAGACACGATG

				
Band lengths: 
118-156

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Pre-implantation embryo development
  • Ribosome-engaged transcriptomes of neuronal types
  • Neural differentiation time course
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types





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