MmuEX0027177 @ mm10
Exon Skipping
Gene
ENSMUSG00000026792 | Lrsam1
Description
leucine rich repeat and sterile alpha motif containing 1 [Source:MGI Symbol;Acc:MGI:2684789]
Coordinates
chr2:32925216-32928733:-
Coord C1 exon
chr2:32928652-32928733
Coord A exon
chr2:32927985-32928130
Coord C2 exon
chr2:32925216-32926901
Length
146 bp
Sequences
Splice sites
3' ss Seq
TGTCCCTCTGATTTCTTCAGAGT
3' ss Score
9.48
5' ss Seq
GAAGTAAGT
5' ss Score
9.82
Exon sequences
Seq C1 exon
GTGGGCGTCTCAGAAGCAGGCCTGCAACATGAGATCCTACGGAGAGCCCAGGACCTGCTAGCTGTGCCTAGGGTCCAGCCAG
Seq A exon
AGTTGAAACCACTCGAGAATGAGGTCCTTGGTGCCCTCGAGCCCCCCACAGCTCCCCGGGAGCTCCAAGAGTCAGTGCGACCGTCCGCCCCCCCAGCTGAACTGGACATGCCGACCTCAGAGTGTGTTGTGTGCCTGGAACGTGAA
Seq C2 exon
GCCCAGATGGTCTTCCTCACCTGTGGCCACGTCTGCTGCTGTCAGCAGTGCTGCCAGCCTCTGCGCACCTGCCCACTGTGCCGCCAGGAGATCTCCCAGCGCCTCCGGATCTACCACAGCAGCTGAAGGCACAGCACCTACCAGCCCTGGCCCTTCCTTGGTACCATCTCCACCACTGCTGGACTCCCACCTACCCTCATTCCCCAGACTAGGGCAAGACTGCCATAGGCCTTTGTCACCCACCACCTGCCACCCCGACCCCCACTGCTCTGAGCACTAGGCAGGCAGGTGGAATGTTCCTGGCCTGTGACATAGCTATTCTGAACAGTGAACAAAAGACAGGGCAAATCTGCTGGTGGTGGAGCCTTGGGGCAGGGGGCCAAGGTCCAGCGTAGGGAGGTGGCCCTGCAGGACTCAGGAATCCATGTTAGTAGCCAAGCCTCAGCGCTACACCCAGCTGTCTGCCCCTCCTGGAGGTGTCCATATCTGTGGAATGTATC
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000026792-'49-51,'49-50,50-51
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (No Ref, Alt. Stop)
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.510 C2=0.000
Domain overlap (PFAM):
C1:
PF0764712=SAM_2=PD(32.2=67.9)
A:
PF139201=zf-C3HC4_3=PU(23.9=22.4)
C2:
PF139201=zf-C3HC4_3=PD(71.7=78.6)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GAGATCCTACGGAGAGCCCAG
R:
GGGAATGAGGGTAGGTGGGAG
Band lengths:
256-402
Functional annotations
There are 2 annotated functions for this event
PMID: 15256501
Encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: mutation analysis, two hybrid. ELM ID: ELMI001342; ELM sequence: TPTAPQ; Overlap: FULL
PMID: 15256501
Encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: mutation analysis, two hybrid. ELM ID: ELMI001343; ELM sequence: RPSAPP; Overlap: FULL
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Pre-implantation embryo development
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types