Special

MmuEX0027259 @ mm9

Exon Skipping

Gene
ENSMUSG00000002020 | Ltbp2
Description
latent transforming growth factor beta binding protein 2 [Source:MGI Symbol;Acc:MGI:99502]
Coordinates
chr12:86131945-86132894:-
Coord C1 exon
chr12:86132772-86132894
Coord A exon
chr12:86132547-86132672
Coord C2 exon
chr12:86131945-86132067
Length
126 bp
Sequences
Splice sites
3' ss Seq
TTCCCATCTTGCCCCTGCAGACG
3' ss Score
11.15
5' ss Seq
AGGGTAAGA
5' ss Score
9.21
Exon sequences
Seq C1 exon
ATGTGGATGAGTGTGAAGGTCCCCAAAGCAGCTGCCGGGGAGGCGAATGCAAGAACACAGAAGGTTCCTACCAATGCCTCTGTCACCAGGGCTTCCAGCTGGTCAATGGCACCATGTGTGAGG
Seq A exon
ACGTGAATGAGTGTGTTGGGGAAGAGCATTGTGCTCCTCACGGCGAGTGCCTCAACAGCCTGGGCTCCTTCTTCTGCCTCTGTGCACCCGGCTTTGCTAGTGCTGAGGGGGGCACCAGATGCCAGG
Seq C2 exon
ATGTTGATGAATGTGCAGCCACAGACCCGTGTCCGGGAGGACACTGTGTCAACACAGAGGGCTCCTTCAGCTGTCTGTGTGAGACTGGCTTCCAGCCCTCCCCAGACAGCGGAGAATGTTTGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000002020-'28-28,'28-27,30-28=AN
Average complexity
A_C1
Mappability confidence:
100%=100=100%
Protein Impact





	

	
Alternative protein isoforms (Ref)





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.000 A=0.000 C2=0.000
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
PF0764510=EGF_CA=WD(100=95.2),PF0764510=EGF_CA=PU(0.1=0.0)

							
A:
PF0764510=EGF_CA=WD(100=95.3),PF0764510=EGF_CA=PU(0.1=0.0)

							
C2:
PF0764510=EGF_CA=WD(100=95.2),PF0764510=EGF_CA=PU(0.1=0.0)

						

					

				








    
Main Inclusion Isoform:
ENSMUSP00000128882





     
                   









    
Main Skipping Isoform:
ENSMUSP00000132067





     
      









    
Other Inclusion Isoforms:
ENSMUSP00000002073, ENSMUSP00000105883, ENSMUSP00000127255, ENSMUSP00000127693
          









    
Other Skipping Isoforms:
NA
  



Associated events






Other assemblies


mm10




Conservation


Human
(hg38)
chr14:74508604-74508729 
HIGH PSI
HsaEX0036910
(LTBP2)
Human
(hg19)
chr14:74975307-74975432 
HIGH PSI
HsaEX0036910
(LTBP2)
Rat
(rn6)
chr6:108512408-108512533 
HIGH PSI
RnoEX0051370
(Ltbp2)
Cow
(bosTau6)
chr10:86195949-86196074 
HIGH PSI
BtaEX6055049
(LTBP2)
Chicken
(galGal4)
chr5:37218629-37218754 
HIGH PSI
GgaEX1034375
(LTBP2)
Chicken
(galGal3)
chr5:40347425-40347550 
HIGH PSI
GgaEX1034375
(LTBP2)
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
GTGGATGAGTGTGAAGGTCCC

				
R: 
AAACATTCTCCGCTGTCTGGG

				
Band lengths: 
242-368

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Pre-implantation embryo development
  • Neural differentiation time course
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types






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