Special

MmuEX0028094 @ mm10

Exon Skipping

Gene
ENSMUSG00000027763 | Mbnl1
Description
muscleblind-like 1 (Drosophila) [Source:MGI Symbol;Acc:MGI:1928482]
Coordinates
chr3:60595594-60613520:+
Coord C1 exon
chr3:60595594-60595764
Coord A exon
chr3:60603694-60603894
Coord C2 exon
chr3:60613263-60613520
Length
201 bp
Sequences
Splice sites
3' ss Seq
CTTTTTGTTTCAATTTGCAGCCA
3' ss Score
9.85
5' ss Seq
GAGGTAGGA
5' ss Score
8.24
Exon sequences
Seq C1 exon
GGTCGTTGCTCCAGAGAGAACTGCAAATATCTTCATCCACCCCCACACTTAAAAACACAGTTAGAGATAAATGGGCGGAATAACTTGATTCAGCAGAAGAACATGGCCATGCTGGCCCAGCAAATGCAGTTAGCCAATGCCATGATGCCCGGTGCCCCGTTGCAGCCCGTG
Seq A exon
CCAATGTTTTCAGTTGCACCAAGCTTAGCCACCAGTGCATCAGCAGCCTTTAACCCTTACCTGGGGCCTGTTTCCCCAAGCCTGGTTCCAGCAGAGATCTTGCCGACTGCACCAATGTTGGTCACGGGGAATCCTGGAGTTCCAGTGCCAGCAGCTGCCGCAGCTGCTGCACAGAAGTTAATGCGGACAGACAGACTGGAG
Seq C2 exon
GTGTGTCGAGAGTACCAGCGTGGCAATTGCAACAGAGGAGAAAATGACTGTCGGTTTGCTCATCCTGCTGACAGCACAATGATTGATACCAATGACAACACAGTCACTGTCTGCATGGATTACATCAAGGGGAGATGCTCTCGGGAAAAGTGCAAATACTTCCATCCTCCCGCACACCTGCAAGCCAAGATCAAGGCTGCCCAATACCAGGTCAACCAGGCTGCAGCAGCACAGGCTGCAGCTACTGCAGCTGCCATG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000027763_MULTIEX1-7/14=5-8
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact





	

	
Alternative protein isoforms (Ref)





No structure available

		

			
Features


			

				
Disorder rate (disopred):
  C1=0.285 A=0.771 C2=0.182
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
PF0064219=zf-CCCH=PU(7.7=3.5)

							
A:
PF0064219=zf-CCCH=PU(11.1=4.5)

							
C2:
PF0064219=zf-CCCH=PD(81.5=25.6)

						

					

				








    
Main Inclusion Isoform:
ENSMUSP00000141287





     
                   









    
Main Skipping Isoform:
ENSMUSP00000141954





     
      









    
Other Inclusion Isoforms:
ENSMUSP00000096686, ENSMUSP00000141474, ENSMUSP00000141536, ENSMUSP00000141576, ENSMUSP00000141915, ENSMUSP00000142045, ENSMUSP00000142057, ENSMUSP00000142074, ENSMUSP00000142088, ENSMUSP00000142095
          









    
Other Skipping Isoforms:
NA
  



Associated events






Other assemblies


mm9




Conservation


Human
(hg38)
chr3:152432717-152432920 
ALTERNATIVE
HsaEX0038109
(MBNL1)
Human
(hg19)
chr3:152150506-152150709 
HIGH PSI
HsaEX0038109
(MBNL1)
Rat
(rn6)
chr2:150846527-150846727 
HIGH PSI
RnoEX0053012
(Mbnl1)
Cow
(bosTau6)
chr1:116265609-116265809 
HIGH PSI
BtaEX6002859
(MBNL1)
Chicken
(galGal4)
chr9:22863561-22863761 
ALTERNATIVE
GgaEX0015490
(MBNL1)
Chicken
(galGal3)
chr9:24969640-24969840 
ALTERNATIVE
GgaEX0015490
(MBNL1_CHICK)
Zebrafish
(danRer10)
chr2:47950836-47951087 
Fruitfly
(dm6)
chr2R:17352129-17352305 
HIGH PSI
DmeEX6011565
(mbl)




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
AGAAGAACATGGCCATGCTGG

				
R: 
GGTTGACCTGGTATTGGGCAG

				
Band lengths: 
294-495

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Pre-implantation embryo development
  • Ribosome-engaged transcriptomes of neuronal types
  • Neural differentiation time course
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types





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