Special

FBgn0265487 @ dm6

Biotype
protein_coding
Gene Symbol
mbl
Description
The gene muscleblind is referred to in FlyBase by the symbol Dmelmbl (CG33197, FBgn0265487). It is a protein_coding_gene from Dmel. It has 19 annotated transcripts and 19 polypeptides (18 unique). Gene sequence location is 2R:17216549..17379376. Its molecular function is described by: RNA binding; metal ion binding; nucleic acid binding. It is involved in the biological process described with 9 unique terms, many of which group under: regulation of nucleobase-containing compound metabolic process; reproductive process; programmed cell death; apoptotic process; organic cyclic compound metabolic process. 93 alleles are reported. The phenotypes of these alleles manifest in: fascicle; larva; rhabdomere; visceral muscle; cytoskeleton. The phenotypic classes of alleles include: increased mortality during development; some die during embryonic stage; phenotype; courtship behavior defective.
Coordinates
chr2R:17216549-17379376:+
Assembly

GENOMIC BROWSER[edit]


EXPRESSION VALUES[edit]


SPECIAL DATASETS

  • Neural diversity
  • Neurogenesis
  • Neuronal activity
  • Splicing factor regulation (brain)
  • Splicing factor regulation (SL2)

EVENTS AND AS PROFILES[edit]

Associated events[edit]

Event
Type
Length
Coordinates
Strand
PSI Average
PSI Range
Annotated Functions
Exon Skipping
654
chr2R:17275410-17276063
+
97.79
27.2
0
Exon Skipping
42
chr2R:17361113-17361154
+
13.26
54.39
6
Exon Skipping
49
chr2R:17220055-17220103
+
91.38
36.11
0
Exon Skipping
33
chr2R:17276746-17276778
+
12.28
95.07
0
Exon Skipping
234
chr2R:17354179-17354412
+
10.96
55
0
Exon Skipping
252
chr2R:17359306-17359557
+
50.05
96.73
0
Exon Skipping
59
chr2R:17371095-17371153
+
15.43
95.63
0
Exon Skipping
85
chr2R:17373077-17373161
+
77.73
76.6
0



Orthologous genes[edit]

Organism Assembly Gene ID Gene Name Orthology Type

Human hg38 ENSG00000076770 MBNL3 1-to-3
Human hg38 ENSG00000139793 MBNL2 1-to-3
Human hg38 ENSG00000152601 MBNL1 1-to-3
Human hg19 ENSG00000076770 MBNL3 1-to-3
Human hg19 ENSG00000139793 MBNL2 1-to-3
Human hg19 ENSG00000152601 MBNL1 1-to-3
Mouse mm10 ENSMUSG00000022139 Mbnl2 1-to-3
Mouse mm10 ENSMUSG00000027763 Mbnl1 1-to-3
Mouse mm10 ENSMUSG00000036109 Mbnl3 1-to-3
Mouse mm9 ENSMUSG00000022139 Mbnl2 1-to-3
Mouse mm9 ENSMUSG00000027763 Mbnl1 1-to-3
Mouse mm9 ENSMUSG00000036109 Mbnl3 1-to-3
Cow bosTau6 ENSBTAG00000004564 MBNL1 1-to-3
Cow bosTau6 ENSBTAG00000014088 MBNL3 1-to-3
Cow bosTau6 ENSBTAG00000018313 MBNL2 1-to-3
Chicken galGal4 ENSGALG00000016890 MBNL2 1-to-3
Chicken galGal3 ENSGALG00000016890 A3F958_CHICK 1-to-3
Zebrafish danRer10 ENSDARG00000016085 mbnl3 1-to-3
Zebrafish danRer10 ENSDARG00000018460 mbnl2 1-to-3
Zebrafish danRer10 ENSDARG00000052978 mbnl1 1-to-3