MmuEX0028275 @ mm9
Exon Skipping
Gene
ENSMUSG00000039842 | Mcph1
Description
microcephaly, primary autosomal recessive 1 [Source:MGI Symbol;Acc:MGI:2443308]
Coordinates
chr8:18641565-18671254:+
Coord C1 exon
chr8:18641565-18641665
Coord A exon
chr8:18668946-18668983
Coord C2 exon
chr8:18671092-18671254
Length
38 bp
Sequences
Splice sites
3' ss Seq
CTCTCTTTTGAAATCTCTAGCCA
3' ss Score
5.94
5' ss Seq
TGAGTAAGT
5' ss Score
8.82
Exon sequences
Seq C1 exon
GTGTTAAAAATGGACCAGGGCGGCCAGATCCTTCAGACAGCTCTTGCACAGGCCTTGTCAGACCTCAGCAGAAACCAAAGAAAAGTGAGAAAGAAGAAAAG
Seq A exon
CCAACGAGAACATTGGTCATGACAAGCATGCCATCTGA
Seq C2 exon
GAAGCAGACCCTCATCATCCAGGTGGTGAGCACACTGAAAGGCTTTTCATTCGCACCCGAGGTCTGCGAGACCACCACCCACGTGCTGGTAGGGAAGTCTGCCCGTACCCTGAACGTGCTGATGGGAATTGCCCGCGGCTGCTGGATTCTTTCTTACGAATGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000039842-'15-15,'15-14,18-15
Average complexity
S*
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.931 A=0.385 C2=0.000
Domain overlap (PFAM):
C1:
NO
A:
PF0053321=BRCT=PU(10.4=53.8)
C2:
PF0053321=BRCT=FE(80.6=100)
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TTAAAAATGGACCAGGGCGGC
R:
CCACCTGGATGATGAGGGTCT
Band lengths:
124-162
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Pre-implantation embryo development
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types
Other AS DBs: