Special

MmuEX0029620 @ mm9

Exon Skipping

Gene
ENSMUSG00000020695 | Mrc2
Description
mannose receptor, C type 2 [Source:MGI Symbol;Acc:MGI:107818]
Coordinates
chr11:105208034-105209081:+
Coord C1 exon
chr11:105208034-105208142
Coord A exon
chr11:105208549-105208787
Coord C2 exon
chr11:105208913-105209081
Length
239 bp
Sequences
Splice sites
3' ss Seq
CCTGCCCCCTTTCCCTGTAGACC
3' ss Score
12.41
5' ss Seq
GAGGTGGGC
5' ss Score
6.32
Exon sequences
Seq C1 exon
ACCAGCTGTGCGGTGATCCTGCACAGCCCCTCAGCCCACTTCACTGGCCGCTGGGATGATCGGAGCTGCACAGAGGAGACGCATGGCTTCATCTGCCAGAAGGGCACAG
Seq A exon
ACCCCTCGCTAAGCCCATCCCCAGCAGCAACACCCCCTGCCCCGGGCGCTGAGCTCTCCTATCTCAACCACACCTTCCGGCTGCTGCAGAAGCCACTGCGCTGGAAAGATGCTCTCCTGCTGTGTGAGAGCCGAAATGCCAGCCTGGCACACGTGCCCGATCCCTACACACAAGCCTTCCTCACACAGGCTGCACGGGGGCTGCAAACACCACTGTGGATCGGGCTGGCCAGTGAGGAG
Seq C2 exon
GGCTCACGGAGGTATTCCTGGCTCTCAGAGGAGCCTCTGAATTATGTGAGCTGGCAAGATGAGGAGCCCCAGCACTCGGGAGGCTGTGCCTACGTGGATGTGGATGGAACCTGGCGCACCACCAGCTGTGATACCAAGCTGCAGGGGGCAGTGTGTGGGGTGAGCAGGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000020695-'26-27,'26-26,27-27
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact





	

	
ORF disruption upon sequence exclusion





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.216 A=0.200 C2=0.018
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
PF0005916=Lectin_C=PD(28.2=89.2)

							
A:
PF0005916=Lectin_C=PU(47.1=61.2)

							
C2:
PF0005916=Lectin_C=PD(51.0=93.0)

						

					

				








    
Main Inclusion Isoform:
ENSMUSP00000097909





     
                   









    
Main Skipping Isoform:
NA





     
      









    
Other Inclusion Isoforms:
NA
          









    
Other Skipping Isoforms:
NA
  



Associated events






Other assemblies


mm10




Conservation


Human
(hg38)
chr17:62689371-62689437 
LOW PSI
HsaEX0040061
(MRC2)
Human
(hg19)
chr17:60766972-60767121 
HIGH PSI
HsaEX0040061
(MRC2)
Rat
(rn6)
chr10:93577482-93577525 
Cow
(bosTau6)
chr19:47744318-47744556 
HIGH PSI
BtaEX6089456
(MRC2)
Chicken
(galGal4)
chr27:2423263-2423501 
HIGH PSI
GgaEX7010951
(MRC2)
Chicken
(galGal3)
chr27:2332610-2332848 
Zebrafish
(danRer10)
chr3:19654132-19654370 
HIGH PSI
DreEX6016099
(MRC2)
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
CAGCTGTGCGGTGATCCTG

				
R: 
CCCTGCTCACCCCACACA

				
Band lengths: 
276-515

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Pre-implantation embryo development
  • Neural differentiation time course
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types






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