Special

MmuEX0035224 @ mm10

Exon Skipping

Gene
Description
gamma-secretase activating protein [Source:MGI Symbol;Acc:MGI:2442259]
Coordinates
chr5:21272982-21287796:+
Coord C1 exon
chr5:21272982-21273043
Coord A exon
chr5:21281508-21281602
Coord C2 exon
chr5:21287553-21287796
Length
95 bp
Sequences
Splice sites
3' ss Seq
CTTTGTTGTTTTTAACTCAGCAA
3' ss Score
4.12
5' ss Seq
CTGGTGAGT
5' ss Score
10.1
Exon sequences
Seq C1 exon
AGCCAAGATTAATACCATTCTTACAAGAGGAAGACCGGCACCAGAGGCTGCTCATGGGCTTG
Seq A exon
CAATAGCCATTGCAGTGCTGCAGATTTTGAAGTCTTTCATCTCATGACCAGGATTTTGGATGCTGCTAGCAGTTTGTGTTTGCCTCTGCCTCCTG
Seq C2 exon
GATTGGCTGACCCAAGCCCTAAGCAAGCTCAGCGCTTGCTTTACTGACAGGATCAATCCATCCTCTCTGGAAGCTGGAGATGCTGGCTCGGCTCGTCATGTCTGCTTCTGTTCCACTCACCTAGGTTTCCACTCTCTGCACACGATCCTTGGGGTCCACTGCCTCCCTTTGTACAGCCTTCTGCACTACATTGATAACGGAGTGCTGCTGCTTACTGAGACCGCGGTCACGAGGCTTATGAAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000039934_MULTIEX3-3/3=C1-C2
Average complexity
C2*
Mappability confidence:
100%=100=100%
Protein Impact

ORF disruption upon sequence exclusion

Show structural model
Features
Disorder rate (Iupred):
  C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):

C1:
NO
A:
PF149591=GSAP-16=FE(27.8=100)
C2:
PF149591=GSAP-16=FE(34.8=100)


Main Inclusion Isoform:


Main Skipping Isoform:
NA


Other Inclusion Isoforms:


Other Skipping Isoforms:
NA
Other assemblies
Conservation
Chicken
(galGal4)
HIGH PSI
Chicken
(galGal3)
HIGH PSI
Zebrafish
(danRer10)
HIGH PSI
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TACAAGAGGAAGACCGGCACC
R:
TGCAGAGAGTGGAAACCTAGGT
Band lengths:
181-276
Functional annotations
There are 0 annotated functions for this event


GENOMIC CONTEXT[edit]

INCLUSION PATTERN[edit]


SPECIAL DATASETS

  • Pre-implantation embryo development
  • Ribosome-engaged transcriptomes of neuronal types
  • Neural differentiation time course
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types