Special

MmuEX0035675 @ mm9

Exon Skipping

Gene
ENSMUSG00000022565 | Plec
Description
plectin [Source:MGI Symbol;Acc:MGI:1277961]
Coordinates
chr15:76023840-76024860:-
Coord C1 exon
chr15:76024771-76024860
Coord A exon
chr15:76024396-76024431
Coord C2 exon
chr15:76023840-76023917
Length
36 bp
Sequences
Splice sites
3' ss Seq
GCCCTGCTCTGGCTGAGCAGCCG
3' ss Score
3.68
5' ss Seq
CTGGTGAGT
5' ss Score
10.1
Exon sequences
Seq C1 exon
GCTCAGAGGCACATCAGTGACCTGTACGAAGACCTCCGTGATGGCCACAACCTCATCTCCCTGCTGGAAGTCCTCTCAGGAGACAGCCTG
Seq A exon
CCGAGGGAGCGGGACGTAATCAGGAGTGTGCGCCTG
Seq C2 exon
CCCCGCGAGAAAGGGAGGATGCGCTTCCACAAGCTGCAGAATGTGCAGATTGCCCTGGACTATCTCCGACATCGCCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000022565_CASSETTE2
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact





	

	
Alternative protein isoforms (No Ref)





Show PDB structure

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.000 A=0.000 C2=0.008
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
PF0030726=CH=FE(28.7=100)

							
A:
PF0030726=CH=FE(9.3=100)

							
C2:
PF0030726=CH=PU(37.3=95.0)

						

					

				








    
Main Inclusion Isoform:
ENSMUSP00000087037





     
                   









    
Main Skipping Isoform:
ENSMUSP00000073124





     
      









    
Other Inclusion Isoforms:
ENSMUSP00000127867, ENSMUSP00000130915
          









    
Other Skipping Isoforms:
ENSMUSP00000023226, ENSMUSP00000057158, ENSMUSP00000071765, ENSMUSP00000072478, ENSMUSP00000073124f1277A, ENSMUSP00000074383, ENSMUSP00000075772, ENSMUSP00000126068, ENSMUSP00000126526, ENSMUSP00000126936, ENSMUSP00000127253
  



Associated events






Other assemblies


mm10




Conservation


Human
(hg38)
chr8:143937749-143937784 
ALTERNATIVE
HsaEX0048199
(PLEC)
Human
(hg19)
chr8:145011917-145011952 
ALTERNATIVE
HsaEX0048199
(PLEC)
Rat
(rn6)
chr7:117253103-117253138 
ALTERNATIVE
RnoEX0066904
(Plec)
Cow
(bosTau6)
chr14:2067168-2067203 
ALTERNATIVE
BtaEX0027492
(PLEC)
Chicken
(galGal4)
chr23:5317624-5317672 
Chicken
(galGal3)
chr23:5631586-5631632 
Zebrafish
(danRer10)
chr19:22881438-22881473 
ALTERNATIVE
DreEX0056138
(pleca)
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
ATCTCCCTGCTGGAAGTCCTC

				
R: 
TGGCGATGTCGGAGATAGTCC

				
Band lengths: 
113-149

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Pre-implantation embryo development
  • Neural differentiation time course
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types






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