Special

MmuEX0036054 @ mm9

Exon Skipping

Gene
ENSMUSG00000004565 | Pnpla6
Description
patatin-like phospholipase domain containing 6 [Source:MGI Symbol;Acc:MGI:1354723]
Coordinates
chr8:3516681-3517407:+
Coord C1 exon
chr8:3516681-3516749
Coord A exon
chr8:3517077-3517164
Coord C2 exon
chr8:3517325-3517407
Length
88 bp
Sequences
Splice sites
3' ss Seq
CTGTGCCGTTCGTTCCGCAGGTG
3' ss Score
13.52
5' ss Seq
AGAGTGAGG
5' ss Score
2.6
Exon sequences
Seq C1 exon
GACTGCAGGCTACAAGACCTGCTACCTAGTCCGAAACAATCGATGGAGGCCCCACTGCAAACCGGAATG
Seq A exon
GTGCTGGGCGTGATGATCGGGGCCGGAGTGGCGGTGCTGGTCACCGCCGTGCTCATCCTCTTGGTGGTGCGAAGGCTGCGGGTGCAGA
Seq C2 exon
AAACTCCAGCCCCGGAGGGTCCCCGGTATCGGTTCCGGAAGCGGGACAAAGTGCTTTTCTATGGCCGGAAGATTATGCGGAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000004565-'4-4,'4-3,8-4
Average complexity
S
Mappability confidence:
100%=83=100%
Protein Impact





	

	
ORF disruption upon sequence exclusion





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.000 A=0.000 C2=0.179
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
NO

							
A:
NO

							
C2:
NO

						

					

				








    
Main Inclusion Isoform:
ENSMUSP00000004681





     
                   









    
Main Skipping Isoform:
NA





     
      









    
Other Inclusion Isoforms:
ENSMUSP00000004681f201A, ENSMUSP00000106699
          









    
Other Skipping Isoforms:
NA
  



Associated events







Other assemblies


mm10




Conservation


Human
(hg38)
chr19:7535933-7536020 
HIGH PSI
HsaEX0048740
(PNPLA6)
Human
(hg19)
chr19:7600819-7600906 
HIGH PSI
HsaEX0048740
(PNPLA6)
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
chr7:17624815-17624902 
HIGH PSI
BtaEX0027733
(PNPLA6)
Chicken
(galGal4)
chrUn_AADN03027100:13950-14037 
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
chr1:45214588-45214675 
HIGH PSI
DreEX6032888
(pnpla6)
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
GACTGCAGGCTACAAGACCTG

				
R: 
CTTCCGCATAATCTTCCGGCC

				
Band lengths: 
152-240

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Pre-implantation embryo development
  • Neural differentiation time course
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types






Retrieved from "https://vastdb.crg.eu/wiki/Special:VastDB"