Special

MmuEX0038418 @ mm9

Exon Skipping

Gene
ENSMUSG00000070953 | Rabepk
Description
Rab9 effector protein with kelch motifs [Source:MGI Symbol;Acc:MGI:2139530]
Coordinates
chr2:34633076-34640215:-
Coord C1 exon
chr2:34640066-34640215
Coord A exon
chr2:34636117-34636266
Coord C2 exon
chr2:34633076-34635049
Length
150 bp
Sequences
Splice sites
3' ss Seq
AAAACTCTCTCTTGTGACAGGTG
3' ss Score
9.09
5' ss Seq
CAGGTGAGT
5' ss Score
10.67
Exon sequences
Seq C1 exon
ACACTCTGACATGGTCTCAACCGGAGACACATGGAAGTCCTCCGTCTCCTCGGCATGGCCATGTGATGGTGGCAGCGGGCACAAAACTCTTCATCCACGGAGGATTGGCAGGGGACAAGTTCTTTGATGATCTCCATTGCATTGATATAG
Seq A exon
GTGACATGAGCTGGCAGAAGCTTGGTCCCACCGGGGCTGTTCCAGTCGGCTGTGCTGCCCATGCCGCCGTTGCTGTGGGACACCATGTATATATGTTTGGAGGTATGACAGCCACTGGAGCACTGAACATGATGTACAAGTATCACACAG
Seq C2 exon
AAAAGCAGCACTGGACTGTACTTCAGTTTGACACTTCCCTACCCGCTGGACGACTGGACCACTCCATGTGTGTCATCCCATGGCCAGTGATGTCTACCTCTGAGAATAAAGACTCAGATTCTGTCATTCTAACCCTCCAAGATGAGAAAGGGGACGCTGCTGAGAAAGCAGAGACCCAGAGTGGAGGACCACACGAGGAGAGTCCAACTACTGTGTTGCTCTGCTTTGTGTTCGGTGGGATGAACACAGAAGGGGAGGTTTATGACGACTGTCTCGTAACTGTAGTGGACTAATAAAGCCCACATTTGTATTACTTGTGACTTTTTACAAAAGTGAAAACTCTGCCGAGCTACACTGCCAAATACTTTTTGCACAATATATTCTCTCATCCCAGTGCGGTGGTGCACACCAGGCATAGTAGCACACACCTTTAATCCCAGCACTTGGGAGGCAGAGGCCAGCCTGGTCTACGTGGTGAGTTCCAGGACAGCCAGAGCTAC
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000070953-'13-11,'13-10,15-11
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact





	

	
Alternative protein isoforms (Ref)





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.301 A=0.000 C2=0.258
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
PF134181=Kelch_4=PD(27.8=29.4),PF134181=Kelch_4=PU(68.0=66.7)

							
A:
PF134181=Kelch_4=PD(30.0=29.4),PF0134420=Kelch_1=PU(79.1=66.7)

							
C2:
PF0134420=Kelch_1=PD(18.6=8.2)

						

					

				








    
Main Inclusion Isoform:
ENSMUSP00000122360





     
                   









    
Main Skipping Isoform:
NA





     
      









    
Other Inclusion Isoforms:
ENSMUSP00000108709, ENSMUSP00000113099
          









    
Other Skipping Isoforms:
NA
  



Associated events






Other assemblies


mm10




Conservation


Human
(hg38)
chr9:125232596-125232745 
HIGH PSI
HsaEX6063025
(RABEPK)
Human
(hg19)
chr9:127994875-127995024 
HIGH PSI
HsaEX6063025
(RABEPK)
Rat
(rn6)
chr3:13847032-13847181 
HIGH PSI
RnoEX0073381
(Rabepk)
Cow
(bosTau6)
chr11:96113252-96113401 
ALTERNATIVE
BtaEX0029433
(RABEPK)
Chicken
(galGal4)
chr17:9590220-9590369 
HIGH PSI
GgaEX1047818
(RABEPK)
Chicken
(galGal3)
chr17:10312215-10312364 
HIGH PSI
GgaEX1047818
(RABEPK)
Zebrafish
(danRer10)
chr5:2453735-2453884 
HIGH PSI
DreEX6008995
(rabepk)
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
TGGCAGGGGACAAGTTCTTTG

				
R: 
TTGGACTCTCCTCGTGTGGTC

				
Band lengths: 
252-402

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Pre-implantation embryo development
  • Neural differentiation time course
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types






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