Special

MmuEX0041441 @ mm9

Exon Skipping

Gene
ENSMUSG00000026924 | Sec16a
Description
SEC16 homolog A (S. cerevisiae) [Source:MGI Symbol;Acc:MGI:2139207]
Coordinates
chr2:26277528-26279516:-
Coord C1 exon
chr2:26279403-26279516
Coord A exon
chr2:26278974-26279157
Coord C2 exon
chr2:26277528-26277773
Length
184 bp
Sequences
Splice sites
3' ss Seq
CTTGACCCTGTTTCCTATAGGAG
3' ss Score
8.82
5' ss Seq
CAGGTGGGG
5' ss Score
6.92
Exon sequences
Seq C1 exon
ATGGCTTCCCAGTTACGCCTCTTCGATCCTCAACTGAAGGAGAAGCCAGAAGAGGAGTCCTTTGTGGAGCCTGCCTGGTTGGTGCAGCTGCAGCACGTGGAGAGGCAGATCCAG
Seq A exon
GAGGGCACTGTGCTGTGGAGCCAGGATGGAACTGAACCCCAGCAGTGTCGCATTACATCGGGCTCTGAGGTGGAGCAGTCAGATGGCCCTGGACTCAACCAGCAGGCAGGGCCACAGGCCGACAACCCTCTACTGATGCCAAGCACTGAGCCTTTGATGCATGGCGTGCAACTGCTGCCCACAG
Seq C2 exon
CTCCTCAGACATTGCCTGATGGCCAGCCTGCTCACCTTTCCAGGGTGCCGATGTTCCCAGTGCCAATGTCTCGTGGGCCCCTGGAGCTGAGTCCTGCCTATGGACCCCCAGGATCTGCACTTGGCTTCCCAGAATCCTCCAGATCTGATCCTGCAGTGCTGCATCCTGGGCAGGCCCTGCCACCCACTACACTAAGTCTCCAGGAAAGTGGGCTTCCACCCCAGGAGGCCAAAAGTCCAGACCCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000026924-'23-27,'23-26,24-27
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact





	

	
ORF disruption upon sequence exclusion





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.058 A=0.916 C2=1.000
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
PF129312=Sec16_C=PD(41.0=89.5)

							
A:
NO

							
C2:
NO

						

					

				








    
Main Inclusion Isoform:
ENSMUSP00000109716f2028A





     
                   









    
Main Skipping Isoform:
NA





     
      









    
Other Inclusion Isoforms:
ENSMUSP00000028290, ENSMUSP00000088796, ENSMUSP00000109716, ENSMUSP00000122255
          









    
Other Skipping Isoforms:
NA
  



Associated events






Other assemblies


mm10




Conservation


Human
(hg38)
chr9:136455601-136455793 
ALTERNATIVE
HsaEX6064036
(SEC16A)
Human
(hg19)
chr9:139350053-139350245 
HIGH PSI
HsaEX6064036
(SEC16A)
Rat
(rn6)
chr3:3870167-3870350 
HIGH PSI
RnoEX0078961
(Sec16a)
Cow
(bosTau6)
chr11:103947229-103947421 
HIGH PSI
BtaEX6047215
(SEC16A)
Chicken
(galGal4)
chr17:7865114-7865318 
HIGH PSI
GgaEX1051395
(SEC16A)
Chicken
(galGal3)
chr17:8554210-8554414 
HIGH PSI
GgaEX1051395
(SEC16A)
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
GCTTCCCAGTTACGCCTCTTC

				
R: 
ATTCTGGGAAGCCAAGTGCAG

				
Band lengths: 
246-430

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Pre-implantation embryo development
  • Neural differentiation time course
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types






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