Special

MmuEX0046405 @ mm9

Exon Skipping

Gene
ENSMUSG00000039678 | Tbc1d13
Description
TBC1 domain family, member 13 [Source:MGI Symbol;Acc:MGI:2385326]
Coordinates
chr2:29997782-30003045:+
Coord C1 exon
chr2:29997782-29997941
Coord A exon
chr2:30002172-30002382
Coord C2 exon
chr2:30002882-30003045
Length
211 bp
Sequences
Splice sites
3' ss Seq
AGGCTCTCCCTTCTCTCCAGATG
3' ss Score
8.77
5' ss Seq
AAGGTAGAC
5' ss Score
7.07
Exon sequences
Seq C1 exon
GAGGTTGTGCCCAGATATATCTTTCTTCCAAAGAGCCACTGAGTACCCCTGCCTGCTCATCCTGGACCCGCAAAATGAGTTTGAGACCCTTCGTAAGCGGGTGGAGCAGACGACACTGAAGTCTCAGACGGTGGCCAGGAATCGAAGCGGGGTTACAAAT
Seq A exon
ATGAGCTCCCCGCACAAGAACAGTGCGCCATCAGCCCTGAACGAGTATGAGGTGCTACCCAATGGCTGCGAAGCCCACTGGGAGGTGGTGGAGCGCATCCTGTTCATCTATGCCAAGCTCAACCCTGGCATCGCTTACGTGCAGGGCATGAATGAGATCGTGGGCCCCCTCTACTACACTTTTGCCACTGACCCTAACAGCGAGTGGAAAG
Seq C2 exon
AGCACGCTGAAGCAGATACCTTTTTCTGCTTCACCAACCTCATGGCTGAGATCCGGGACAACTTCATCAAGAGCCTGGATGACTCCCAGTGCGGTATCACCTACAAGATGGAAAAGGTGTACTCCACCTTGAAGGATAAGGATGTAGAGCTCTACCTGAAGCTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000039678_MULTIEX2-2/3=1-3
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact





	

	
ORF disruption upon sequence exclusion





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.259 A=0.113 C2=0.000
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
NO

							
A:
PF0056613=RabGAP-TBC=PU(29.3=67.6)

							
C2:
PF0056613=RabGAP-TBC=FE(32.9=100),PF038478=TFIID_20kDa=PU(93.6=80.0)

						

					

				








    
Main Inclusion Isoform:
ENSMUSP00000048426





     
                   









    
Main Skipping Isoform:
NA





     
      









    
Other Inclusion Isoforms:
NA
          









    
Other Skipping Isoforms:
NA
  



Associated events






Other assemblies


mm10




Conservation


Human
(hg38)
chr9:128803250-128803460 
HIGH PSI
HsaEX0063770
(TBC1D13)
Human
(hg19)
chr9:131565529-131565739 
HIGH PSI
HsaEX0063770
(TBC1D13)
Rat
(rn6)
chr3:8712991-8713201 
HIGH PSI
RnoEX0088794
(Tbc1d13)
Cow
(bosTau6)
chr11:99307623-99307830 
HIGH PSI
BtaEX6046529
(TBC1D13)
Chicken
(galGal4)
chr17:5269100-5269307 
Chicken
(galGal3)
chr17:5897282-5897489 
ALTERNATIVE
GgaEX0006330
(TBC1D13)
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
AAGAGCCACTGAGTACCCCTG

				
R: 
CAGCTTCAGGTAGAGCTCTAC

				
Band lengths: 
294-505

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Pre-implantation embryo development
  • Neural differentiation time course
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types






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