MmuEX0049250 @ mm9
Exon Skipping
Gene
ENSMUSG00000026812 | Tsc1
Description
tuberous sclerosis 1 [Source:MGI Symbol;Acc:MGI:1929183]
Coordinates
chr2:28514125-28518133:+
Coord C1 exon
chr2:28514125-28514310
Coord A exon
chr2:28517102-28517205
Coord C2 exon
chr2:28517981-28518133
Length
104 bp
Sequences
Splice sites
3' ss Seq
GAGTCGCTCTTTTTGTTTAGAAC
3' ss Score
5.61
5' ss Seq
AAGGTGAGT
5' ss Score
10.47
Exon sequences
Seq C1 exon
TCTGGTAGTGGCCCTAATGAAGAGCTGTGCAAACCTTTAGCACACGTCCTGGAGCCCACACAGCAGAGTTGAGTGAGAGAATGGCCCAGTTAGCCAACATTGGGGAGCTGCTCTCCATGCTGGACTCCTCCACACTGGGTGTGCGGGATGACGTGACAGCCATCTTCAAGGAGTCCCTCAATTCTG
Seq A exon
AACGTGGGCCTATGCTTGTCAACACGTTGGTTGATTATTACCTGGAAACCAATTCTCAGCCGGTATTGCACATCCTGACCACCTTGCAGGAGCCACACGATAAG
Seq C2 exon
CACCTCTTGGACAAAATTAATGAGTATGTAGGCAAAGCTGCTACCCGTTTATCCATCCTCTCGCTGCTGGGGCATGTTGTGAGACTGCAGCCATCTTGGAAGCATAAGCTCTCTCAAGCACCTCTTCTGCCTTCTTTATTGAAATGTCTCAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000026812-'7-7,'7-6,8-7
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF043887=Hamartin=PU(4.8=94.4)
A:
PF043887=Hamartin=FE(4.8=100)
C2:
PF043887=Hamartin=FE(11.0=100)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGAGTGAGAGAATGGCCCAGT
R:
AGGCAGAAGAGGTGCTTGAGA
Band lengths:
249-353
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Pre-implantation embryo development
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types
Other AS DBs: