Special

MmuEX0051692 @ mm9

Exon Skipping

Gene
ENSMUSG00000001930 | Vwf
Description
Von Willebrand factor homolog [Source:MGI Symbol;Acc:MGI:98941]
Coordinates
chr6:125599135-125606826:+
Coord C1 exon
chr6:125599135-125599312
Coord A exon
chr6:125605050-125605270
Coord C2 exon
chr6:125606634-125606826
Length
221 bp
Sequences
Splice sites
3' ss Seq
CATTGGCTTTCCCCACTCAGGTG
3' ss Score
8.83
5' ss Seq
GAGGTGAGA
5' ss Score
7.66
Exon sequences
Seq C1 exon
CCTGGGGATGTCTGGACCTTGCCGGATCAGTGCCACACAGTGACTTGCTTGGCAAATGGCCAGACCTTGCTGCAGAGTCATCGTGTCAATTGTGACCATGGACCCCGGCCTTCATGTGCCAACAGCCAGTCTCCTGTTCGGGTGGAGGAGACGTGTGGCTGCCGCTGGACCTGCCCTT
Seq A exon
GTGTGTGCACGGGCAGTTCCACTCGGCACATCGTCACCTTCGATGGGCAGAATTTCAAGCTTACTGGTAGCTGCTCCTATGTCATCTTTCAAAACAAGGAGCAGGACCTGGAAGTGCTCCTCCACAATGGGGCCTGCAGCCCCGGGGCAAAACAAGCCTGCATGAAGTCCATTGAGATTAAGCATGCTGGCGTCTCTGCTGAGCTGCACAGTAACATGGAG
Seq C2 exon
ATGGCAGTGGATGGGAGACTGGTCCTTGCCCCGTACGTTGGTGAAAACATGGAAGTCAGCATCTACGGCGCTATCATGTATGAAGTCAGGTTTACCCATCTTGGCCACATCCTCACATACACGCCACAAAACAACGAGTTCCAACTGCAGCTTAGCCCCAAGACCTTTGCTTCGAAGATGCATGGTCTTTGCG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000001930_CASSETTE1
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact





	

	
ORF disruption upon sequence exclusion





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.017 A=0.000 C2=0.000
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
NO

							
A:
PF0009420=VWD=PU(46.4=95.9)

							
C2:
PF0009420=VWD=FE(41.8=100)

						

					

				








    
Main Inclusion Isoform:
ENSMUSP00000107873





     
                   









    
Main Skipping Isoform:
NA





     
      









    
Other Inclusion Isoforms:
ENSMUSP00000001995
          









    
Other Skipping Isoforms:
NA
  



Associated events






Other assemblies


mm10




Conservation


Human
(hg38)
chr12:5996002-5996222 
HIGH PSI
HsaEX6064664
(VWF)
Human
(hg19)
chr12:6105168-6105388 
HIGH PSI
HsaEX6064664
(VWF)
Rat
(rn6)
chr4:158187665-158187885 
HIGH PSI
RnoEX0098738
(Vwf)
Cow
(bosTau6)
chr5:104688849-104689069 
HIGH PSI
BtaEX6024541
(VWF)
Chicken
(galGal4)
chr1:74377358-74377578 
HIGH PSI
GgaEX1063606
(VWF)
Chicken
(galGal3)
chr1:76605135-76605355 
HIGH PSI
GgaEX1063606
(VWF)
Zebrafish
(danRer10)
chr18:7237094-7237308 
HIGH PSI
DreEX6064146
(vwf)
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
ACACAGTGACTTGCTTGGCAA

				
R: 
GGCTAAGCTGCAGTTGGAACT

				
Band lengths: 
301-522

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Pre-implantation embryo development
  • Neural differentiation time course
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types






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