Special

MmuEX0053553 @ mm9

Exon Skipping

Gene
ENSMUSG00000048921 | Zfp689
Description
zinc finger protein 689 [Source:MGI Symbol;Acc:MGI:1918381]
Coordinates
chr7:134587266-134592672:-
Coord C1 exon
chr7:134592168-134592672
Coord A exon
chr7:134591877-134591990
Coord C2 exon
chr7:134587266-134588651
Length
114 bp
Sequences
Splice sites
3' ss Seq
GACTGGTTCTCCTTCCCCAGGAT
3' ss Score
8.94
5' ss Seq
GAAGTGAGT
5' ss Score
7.97
Exon sequences
Seq C1 exon
CGCCATTACACTTTAGGGCAAGGAGGTTAAGAAGTCGGCATGGCGTTCGGGTCAATAAAATCGATAGCTGGAACCTGCCTGTGTTCTAGGCAGCGGTGGTGCAGGAGCAGCGCCGCCATCTTCCCCGAAGGCATCTTCCGGTGCCTCTCACCCAAGTTCCAGCGGGAGTTCCCTGAATAACGGTCTGTGTCGGGCCGCCCGGCCCCTCAGGCAGCCGATTCAGATTTCCTCCGGGCCTTCCCGACGGAGCTTCTAGGTCTCCGGGTCCCCGTGGCAAGGCCGGGGAGCAGGTCCGATGGCGCCACCTTCGGCTCCGCTTCTCCTGCGGGCAGTCGGAGAGGCTGGACCTACTCGGAAAAGGGGCAGGAGGCCAAGGGCCTTGAAGTTCGTGGACGTGGCCGTGTACTTCTCCTCGGAGGAGTGGGGGTGTCTGCAGCCCGCTCAGAGGACTCTGTACCGGGATGTGATGCGCGAGACCTACGGCCTCCTGGGCGCGCTCG
Seq A exon
GATGCGCAGGTCCCAAACCAGCTCTCATCTCCTGGTTGGAACGAAATACCGATGACTGGGAACCAGCAGCCCTAGATCCGCAGGAGTACCGGAGATGGGTAACATTCCAGAGAA
Seq C2 exon
AAACCAGATCCAAGCAGAAGACTGAAGAGAAGGACGTATTCCCACCTAAGGAAGCACCCCGAAAGGGGAAACGAGGGCGGAAGCCCAGCAAACCCCGGCTGATTCCCAGGCAGACATCCGGGGGCCCCATCTGCCCTGACTGTGGCTGTACCTTTCCTGACCACCTCGCCCTGGAGAGCCACAAGTGCGCCCAGAATCTGAAGAAACCCTATCCCTGCCCGGATTGTGGGCGTCGCTTTTCCTACCCATCCCTGTTGGTCAGTCACCGGCGGGCACACTCCGGTGAGTGCCCTTACGTTTGTGACCAGTGTGGCAAACGTTTTTCCCAGAGGAAAAACCTGTCTCAGCACCAGGTCATACACACAGGCGAGAAGCCCTACCACTGCCCTGACTGTGGCCGCTGCTTTCGCAGGAGCCGGTCGTTGGCCAATCACCGGACCACGCACACCGGTGAGAAGCCTCATCAGTGCCCTAGTTGTGGGCGTCGCTTCGCCTATCCA
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000048921-'0-1,'0-0,1-1
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact





	

	
Alternative protein isoforms (Ref)





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.130 A=0.077 C2=0.159
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
PF0135222=KRAB=WD(100=59.4)

							
A:
PF0135222=KRAB=PD(0.1=0.0)

							
C2:
PF0009621=zf-C2H2=WD(100=5.8),PF134651=zf-H2C2_2=WD(100=6.6),PF134651=zf-H2C2_2=WD(100=6.6),PF134651=zf-H2C2_2=WD(100=6.6),PF134651=zf-H2C2_2=WD(100=6.6),PF134651=zf-H2C2_2=WD(100=6.6),PF134651=zf-H2C2_2=WD(100=6.6),PF134651=zf-H2C2_2=WD(100=6.6),PF134651=zf-H2C2_2=WD(100=6.6),PF134651=zf-H2C2_2=WD(100=6.6)

						

					

				








    
Main Inclusion Isoform:
ENSMUSP00000056610





     
                   









    
Main Skipping Isoform:
NA





     
      









    
Other Inclusion Isoforms:
ENSMUSP00000101906
          









    
Other Skipping Isoforms:
NA
  



Associated events






Other assemblies


mm10




Conservation


Human
(hg38)
chr16:30609525-30609638 
HIGH PSI
HsaEX6043238
(ZNF689)
Human
(hg19)
chr16:30620846-30620959 
HIGH PSI
HsaEX6043238
(ZNF689)
Rat
(rn6)
chr1:198899305-198899418 
ALTERNATIVE
RnoEX0101583
(Zfp629)
Cow
(bosTau6)
chr25:27017923-27018036 
HIGH PSI
BtaEX0041496
(ZNF689)
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
chrUn_random:28934022-28934136 
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
AGGACTCTGTACCGGGATGTG

				
R: 
CTTCAGATTCTGGGCGCACTT

				
Band lengths: 
258-372

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Pre-implantation embryo development
  • Neural differentiation time course
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types






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