MmuEX0054155 @ mm10
Exon Skipping
Gene
ENSMUSG00000039842 | Mcph1
Description
microcephaly, primary autosomal recessive 1 [Source:MGI Symbol;Acc:MGI:2443308]
Coordinates
chr8:18668946-18689059:+
Coord C1 exon
chr8:18668946-18668983
Coord A exon
chr8:18671092-18671254
Coord C2 exon
chr8:18688982-18689059
Length
163 bp
Sequences
Splice sites
3' ss Seq
GTTGACTCTCTGGTCCACAGGAA
3' ss Score
7.88
5' ss Seq
TGGGTAAGC
5' ss Score
8.84
Exon sequences
Seq C1 exon
CCAACGAGAACATTGGTCATGACAAGCATGCCATCTGA
Seq A exon
GAAGCAGACCCTCATCATCCAGGTGGTGAGCACACTGAAAGGCTTTTCATTCGCACCCGAGGTCTGCGAGACCACCACCCACGTGCTGGTAGGGAAGTCTGCCCGTACCCTGAACGTGCTGATGGGAATTGCCCGCGGCTGCTGGATTCTTTCTTACGAATGG
Seq C2 exon
GTACTGTTGTCTTTAGAGTTGGGCCACTGGATTTCTGAGGAGCCTTTTGAACTCTCTGAAACCTTCCCTGCAGCTCCG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000039842_MULTIEX1-10/12=9-11
Average complexity
S*
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.385 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0053321=BRCT=PU(10.4=53.8)
A:
PF0053321=BRCT=FE(80.6=100)
C2:
PF0053321=BRCT=PD(6.0=15.4)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CCAACGAGAACATTGGTCATGAC
R:
GAGCTGCAGGGAAGGTTTCAG
Band lengths:
114-277
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types