Special

MmuEX6015132 @ mm9

Exon Skipping

Gene
ENSMUSG00000054065 | Pkp3
Description
plakophilin 3 [Source:MGI Symbol;Acc:MGI:1891830]
Coordinates
chr7:148268454-148270158:+
Coord C1 exon
chr7:148268454-148269085
Coord A exon
chr7:148269162-148269285
Coord C2 exon
chr7:148269954-148270158
Length
124 bp
Sequences
Splice sites
3' ss Seq
CTAAACCCCTGATTCTACAGCTT
3' ss Score
5.92
5' ss Seq
CAGGTGATA
5' ss Score
4.58
Exon sequences
Seq C1 exon
GGGGGTACCCAGCCCACTCCACCTATGCCCACCCGGCCAGTGTCCTTCCATGAGCGAGGTGGGGCAGCCAGCAGAGCTGACTATGACACATTATCCCTGCGCTCACTGAGGCTGGGGCCAGGGGGCCTGGATGACCGTTACAGCGTGGTATCTGAGCAACTGGAGCCTGCAGCCGCCTCTACCTACAGGGCCTATGCTTACGAGCGCCAGGCTAGCTCCGGCTCTAGCCGAGCAGGGGGCCTGGACTGGCCAGAGGCCACAGAGGGACCACCCAGCAGGACCATCCGTGCACCTGCCATGCGAACCCTGCAAAGATTTCAGAGCAGCCACCGAAGCCGTGGGGGTACCGGGTCAGTGTCAGGTGCCGGCTTGGAGCCAGTGGCCCGAGCCCCATCTGTGCGCAGCCTCAGTCTTAGCCTGGCTGACTCAGGCCACCTGCCAGATGTACGCGGGCTGGACAGCTACACGGGCCATCGAACCCTGCAGAGGCTCAGCAGTGG
Seq A exon
CTTTGATGACATTGACCTGCCTTCAGCAGTCAAGTACCTCATGGCCTCAGACCCCAACCTGCAGGTGCTGGGAGCAGCTTACATCCAGCACAGGTGTTACAGTGATGCCGCCGCCAAGAAGCAG
Seq C2 exon
GCTCGCAGCCTTCAGGCAGTGCCTAGACTGGTGAAGCTCTTCAACCACGCCAACCAGGAGGTGCAGCGCCACGCCACAGGTGCCATGCGCAACCTCATCTACGACAATGTAGACAACAAGCTGGCGTTGGTAGAGGAGAATGGCATTTTTGAGCTGTTGCGGACACTTCGAGAGCAGGATGATGAGCTACGCAAAAATGTTACAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000054065-'9-10,'9-9,10-10=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact





	

	
ORF disruption upon sequence exclusion





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.577 A=0.000 C2=0.000
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
NO

							
A:
PF0051418=Arm=PU(14.6=14.3)

							
C2:
PF0051418=Arm=PD(80.5=47.8),PF0051418=Arm=PU(80.5=47.8)

						

					

				








    
Main Inclusion Isoform:
ENSMUSP00000101654





     
                   









    
Main Skipping Isoform:
NA





     
      









    
Other Inclusion Isoforms:
ENSMUSP00000069961
          









    
Other Skipping Isoforms:
NA
  



Associated events






Other assemblies


mm10




Conservation


Human
(hg38)
No conservation detected
Human
(hg19)
chr11:397539-397662 
HIGH PSI
HsaEX6000061
(PKP3)
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
chr29:51276173-51276296 
HIGH PSI
BtaEX6104461
(PKP3)
Chicken
(galGal4)
chr5:1565069-1565192 
ALTERNATIVE
GgaEX0005661
(PKP3)
Chicken
(galGal3)
chr5:1583724-1583847 
HIGH PSI
GgaEX0005661
(PKP3)
Zebrafish
(danRer10)
chr7:32691572-32691695 
HIGH PSI
DreEX6005968
(PKP3 (2 of 2))
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
TCTTAGCCTGGCTGACTCAGG

				
R: 
AGTGTCCGCAACAGCTCAAAA

				
Band lengths: 
257-381

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]










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