HsaEX6000061 @ hg19
Exon Skipping
Gene
ENSG00000184363 | PKP3
Description
plakophilin 3 [Source:HGNC Symbol;Acc:9025]
Coordinates
chr11:396814-399196:+
Coord C1 exon
chr11:396814-397445
Coord A exon
chr11:397539-397662
Coord C2 exon
chr11:398992-399196
Length
124 bp
Sequences
Splice sites
3' ss Seq
CCTGACCCCTGGCTCCGCAGTTT
3' ss Score
7.02
5' ss Seq
CAGGTGACC
5' ss Score
6.54
Exon sequences
Seq C1 exon
GGGGGTGCCCAGCCCACCCCTCCCATGCCCACCAGGCCCGTGTCCTTCCATGAGCGCGGTGGGGTTGGGAGCCGGGCCGACTATGACACACTCTCCCTGCGCTCGCTGCGGCTGGGGCCCGGGGGCCTGGACGACCGCTACAGCCTGGTGTCTGAGCAGCTGGAGCCCGCGGCCACCTCCACCTACAGGGCCTTTGCGTACGAGCGCCAGGCCAGCTCCAGCTCCAGCCGGGCAGGGGGGCTGGACTGGCCCGAGGCCACTGAGGTTTCCCCGAGCCGGACCATCCGTGCCCCTGCCGTGCGGACCCTGCAGCGATTCCAGAGCAGCCACCGGAGCCGCGGGGTAGGCGGGGCAGTGCCGGGGGCCGTCCTGGAGCCAGTGGCTCGAGCGCCATCTGTGCGCAGCCTCAGCCTCAGCCTGGCTGACTCGGGCCACCTGCCGGACGTGCATGGGTTCAACAGCTACGGTAGCCACCGAACCCTGCAGAGACTCAGCAGCGG
Seq A exon
TTTTGATGACATTGACCTGCCCTCAGCAGTCAAGTACCTCATGGCTTCAGACCCCAACCTGCAGGTGCTGGGAGCGGCCTACATCCAGCACAAGTGCTACAGCGATGCAGCCGCCAAGAAGCAG
Seq C2 exon
GCCCGCAGCCTTCAGGCCGTGCCTAGGCTGGTGAAGCTCTTCAACCACGCCAACCAGGAAGTGCAGCGCCATGCCACAGGTGCCATGCGCAACCTCATCTACGACAACGCTGACAACAAGCTGGCCCTGGTGGAGGAGAACGGGATCTTCGAGCTGCTGCGGACACTGCGGGAGCAGGATGATGAGCTTCGCAAAAATGTCACAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000184363-'2-3,'2-2,3-3=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.403 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
NO
A:
PF0051418=Arm=PU(14.6=14.3)
C2:
PF0051418=Arm=PD(80.5=47.8),PF0051418=Arm=PU(80.5=47.8)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGCATGGGTTCAACAGCTACG
R:
CGAAGCTCATCATCCTGCTCC
Band lengths:
246-370
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)