Special

MmuEX6021312 @ mm10

Exon Skipping

Description
argininosuccinate lyase [Source:MGI Symbol;Acc:MGI:88084]
Coordinates
chr5:130018310-130018916:-
Coord C1 exon
chr5:130018833-130018916
Coord A exon
chr5:130018548-130018604
Coord C2 exon
chr5:130018310-130018407
Length
57 bp
Sequences
Splice sites
3' ss Seq
CTCATGCCTCTTCACTCCAGGAA
3' ss Score
8.6
5' ss Seq
CAGGTGTCC
5' ss Score
3.16
Exon sequences
Seq C1 exon
GTTGCTGAAGAGTGGGCCCAAGGCACCTTCAAATTACATCCTAATGATGAAGACATCCACACAGCCAACGAGCGGCGCCTGAAG
Seq A exon
GAACTCATCGGTGAAGCTGCAGGGAAGCTACACACAGGACGAAGTCGCAACGACCAG
Seq C2 exon
GTGGTCACGGACCTCAGGCTGTGGATGAGGCAGACCTGCTCAAAACTCTCCGCCCTCCTCCGGGTGCTCATTGGAACCATGGTCGACCGGGCAGAGGC
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000025533-'12-18,'12-17,13-18
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact

Alternative protein isoforms (Ref)

No structure available
Features
Disorder rate (Iupred):
  C1=0.071 A=0.000 C2=0.000
Domain overlap (PFAM):

C1:
PF0020615=Lyase_1=FE(10.7=100)
A:
PF0020615=Lyase_1=FE(6.1=100)
C2:
PF0020615=Lyase_1=FE(10.8=100)


Main Inclusion Isoform:


Main Skipping Isoform:
NA


Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal4)
HIGH PSI
Zebrafish
(danRer10)
HIGH PSI
(asl)
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TTGCTGAAGAGTGGGCCCAAG
R:
GCGGAGAGTTTTGAGCAGGTC
Band lengths:
136-193
Functional annotations
There are 0 annotated functions for this event


GENOMIC CONTEXT[edit]

INCLUSION PATTERN[edit]


SPECIAL DATASETS

  • Ribosome-engaged transcriptomes of neuronal types
  • Neural differentiation time course
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types