Special

MmuEX6021423 @ mm9

Exon Skipping

Gene
ENSMUSG00000063146 | Clip2
Description
CAP-GLY domain containing linker protein 2 [Source:MGI Symbol;Acc:MGI:1313136]
Coordinates
chr5:134992686-134999012:-
Coord C1 exon
chr5:134998456-134999012
Coord A exon
chr5:134993777-134993901
Coord C2 exon
chr5:134992686-134992899
Length
125 bp
Sequences
Splice sites
3' ss Seq
CTCTCTCCATGTGCCAACAGGTT
3' ss Score
9.83
5' ss Seq
CAGGTACAA
5' ss Score
7.09
Exon sequences
Seq C1 exon
TCTCTGAGAAGCCAGGTCCAAAGGCGGCTGAAGTGGGTGATGACTTCCTGGGAGACTTTGTGGTGGGCGAGAGGGTGTGGGTGAATGGCGTGAAGCCAGGCGTGGTGCAGTACCTGGGTGAGACACAGTTTGCGCCAGGCCAGTGGGCCGGCGTGGTCTTGGACGACCCGGTGGGCAAGAACGATGGAGCTGTGGGTGGCGTGCGCTACTTCGAGTGCCCGGCTCTACAGGGCATCTTCACGCGGCCCTCCAAGCTGACCCGCCAGCCCACCGCTGAGGGCTCGGGCAGTGATACGCACTCGGTGGAATCCCTCACGGCCCAGAACCTGTCCCTGCATTCTGGCACGGCCACGCCCCCACTCACAGGCCGAGTCATCCCCCTGCGGGAGAGTGTTCTTAACAGCTCAGTGAAGACGGGCAATGAGTCTGGTTCCAACCTCTCCGACAGTGGTTCTGTGAAGCGCGGTGACAAGGACCTCCACCTGGGAGACCGTGTGCTG
Seq A exon
GTTGGTGGGACGAAGACCGGTGTGGTGCGATATGTTGGGGAGACGGACTTTGCCAAAGGCGAGTGGTGTGGTGTGGAGCTGGATGAGCCCCTCGGGAAGAACGACGGGGCGGTGGCAGGAACCAG
Seq C2 exon
GTACTTCCAGTGCCCACCCAAGTTCGGTCTCTTTGCACCAATCCACAAGGTCATCCGAATTGGCTTCCCATCCACCAGTCCAGCCAAGGCCAAGAAGACCAAACGCATGGCCATGGGTGTCTCCGCTTTGACCCACAGCCCCAGCAGCTCTTCCATTAGCTCTGTCAGCTCTGTGGCCTCCTCTGTTGGTGGCCGGCCCAGCCGCAGTGGCCTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000063146-'3-4,'3-3,4-4=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact





	

	
ORF disruption upon sequence exclusion





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.543 A=0.048 C2=0.403
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
PF0130220=CAP_GLY=WD(100=35.5),PF0130220=CAP_GLY=PU(7.6=2.7)

							
A:
PF0130220=CAP_GLY=FE(62.1=100)

							
C2:
PF0130220=CAP_GLY=PD(27.3=25.0),PF116003=CAF-1_p150=PU(23.2=61.1)

						

					

				








    
Main Inclusion Isoform:
ENSMUSP00000098212





     
                   









    
Main Skipping Isoform:
NA





     
      









    
Other Inclusion Isoforms:
ENSMUSP00000037431
          









    
Other Skipping Isoforms:
NA
  



Associated events






Other assemblies


mm10




Conservation


Human
(hg38)
chr7:74353880-74354004 
ALTERNATIVE
HsaEX0015680
(CLIP2)
Human
(hg19)
chr7:73768210-73768334 
ALTERNATIVE
HsaEX0015680
(CLIP2)
Rat
(rn6)
chr12:25207283-25207407 
HIGH PSI
RnoEX0021807
(Clip2)
Cow
(bosTau6)
chr25:33597938-33598062 
HIGH PSI
BtaEX6110180
(CLIP2)
Chicken
(galGal4)
chr19_AADN03010820_random:5158-5282 
Chicken
(galGal3)
chr19:2761920-2762044 
HIGH PSI
GgaEX6016944
(CLIP2)
Zebrafish
(danRer10)
chr5:58766765-58766889 
HIGH PSI
DreEX6013885
(clip2)
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
GAAGACGGGCAATGAGTCTGG

				
R: 
GCTAATGGAAGAGCTGCTGGG

				
Band lengths: 
251-376

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]










Retrieved from "https://vastdb.crg.eu/wiki/Special:VastDB"