Special

MmuEX6054405 @ mm10

Exon Skipping

Gene
ENSMUSG00000022565 | Plec
Description
plectin [Source:MGI Symbol;Acc:MGI:1277961]
Coordinates
chr15:76183362-76184105:-
Coord C1 exon
chr15:76183967-76184105
Coord A exon
chr15:76183523-76183879
Coord C2 exon
chr15:76183362-76183445
Length
357 bp
Sequences
Splice sites
3' ss Seq
CACCCTGCCTTGCCCAACAGAAG
3' ss Score
8.41
5' ss Seq
AAGGTAGGT
5' ss Score
10.29
Exon sequences
Seq C1 exon
ACTCAAGACCATCAGCTTGGTGATTCGCAGTACCCAGGGGGCTGAGGAGGTGCTTAAAACCCATGAGGAGCAGCTGAAGGAGGCCCAGGCTGTGCCTGCCACTCTCCAAGAGCTTGAAGCCACCAAGGCCTCACTAAAG
Seq A exon
AAGCTGCGGGCCCAGGCCGAGGCACAGCAGCCAGTATTCAACACCCTAAGAGATGAGTTGCGGGGGGCACAGGAGGTTGGTGAGCGGCTACAGCAGCGGCATGGTGAGCGGGACGTAGAAGTTGAGCGCTGGCGAGAACGTGTCACTCAGTTGCTGGAGCGCTGGCAGGCTGTTCTAGCCCAGACAGATGTGCGGCAGCGTGAGCTCGAGCAGCTGGGCCGCCAGCTTCGCTACTATCGTGAGAGCGCGGATCCTCTGAGCGCCTGGCTGCAGGATGCCAAGAGGCGGCAAGAGCAGATCCAGGCCGTGCCAATAGCCAACTGTCAGGCTGCGCGAGAACAGCTGCGCCAGGAGAAG
Seq C2 exon
GCCCTGCTGGAGGAGATTGAGCGTCATGGTGAGAAGGTTGAGGAGTGCCAGAAGTTTGCTAAGCAGTACATCAATGCAATCAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000022565-'61-58,'61-56,62-58=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact





	

	
Alternative protein isoforms (Ref)





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.234 A=0.101 C2=0.000
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
PF0043516=Spectrin=PU(33.9=78.7)

							
A:
PF0043516=Spectrin=PD(64.2=58.8)

							
C2:
NO

						

					

				








    
Main Inclusion Isoform:
ENSMUSP00000073124





     
                   









    
Main Skipping Isoform:
NA





     
      









    
Other Inclusion Isoforms:
ENSMUSP00000023226, ENSMUSP00000057158, ENSMUSP00000071765, ENSMUSP00000072478, ENSMUSP00000074383, ENSMUSP00000075772, ENSMUSP00000079668, ENSMUSP00000087037, ENSMUSP00000126068, ENSMUSP00000126526, ENSMUSP00000127261, ENSMUSP00000129543, ENSMUSP00000130048
          









    
Other Skipping Isoforms:
NA
  



Associated events






Other assemblies


mm9




Conservation


Human
(hg38)
chr8:143927410-143927766 
HIGH PSI
HsaEX6082844
(PLEC)
Human
(hg19)
chr8:145001578-145001934 
HIGH PSI
HsaEX6082844
(PLEC)
Rat
(rn6)
chr7:117242840-117243196 
HIGH PSI
RnoEX6032776
(Plec)
Cow
(bosTau6)
chr14:2076785-2077141 
HIGH PSI
BtaEX6061401
(PLEC)
Chicken
(galGal4)
chr23:5336225-5336545 
Chicken
(galGal3)
chr23:5651394-5651556 
HIGH PSI
GgaEX6025274
(MACF1)
Zebrafish
(danRer10)
chr19:22842604-22842960 
HIGH PSI
DreEX0056151
(pleca)
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
ACTCAAGACCATCAGCTTGG

				
R: 
CTTGATTGCATTGATGTACTGCT

				
Band lengths: 
223-580

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Ribosome-engaged transcriptomes of neuronal types
  • Neural differentiation time course
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types





Retrieved from "https://vastdb.crg.eu/wiki/Special:VastDB"