MmuEX6100061 @ mm10
Exon Skipping
Gene
ENSMUSG00000043535 | Setx
Description
senataxin [Source:MGI Symbol;Acc:MGI:2443480]
Coordinates
chr2:29144603-29150107:+
Coord C1 exon
chr2:29144603-29147653
Coord A exon
chr2:29148434-29148721
Coord C2 exon
chr2:29150008-29150107
Length
288 bp
Sequences
Splice sites
3' ss Seq
GCAATATTTTTCATTTTCAGACT
3' ss Score
8.87
5' ss Seq
ACAGTAAGT
5' ss Score
9.49
Exon sequences
Seq C1 exon
ACTCAAAACCTGTTAGGAAAGTTCCAGCCTCTAAGGCAACTAAGAAAACACATTCAGACACCAGAAGAGGACAGTCTAAGAGTTCATGTTACATAAGTTGTAGAACTTCTCCTGCTATTGTGCCACCAAAGAAGCTTCGTCAGTGTCCAGAGCCAACTTCAACAGTTGAAAAACTTGGTCTGAAAAAAGCCCCTAGGAAGGCATTTGAGTTGTCCCAGAGGTCTCTGGAGTGTATAGTCCAATTACGTGACCACGGGAAGACTGTTGGAGTAGTTGACGCCCCCAAGAAAGCTAAATTAATTTCTCCTCAGACTCTTTCTATCAAAAATAATAAGAAGCTTCTGACAAGCCAGGATCTTCAATTTCAAAGGCTTATGAGATCCAGATCACATAAAAAACGAGACTTTGATTACAAAAATACTGATACTGTAAGAGTGTCACGCATAGTACAGGGATCAGATGTACTTGAAGCAGACTCTGATGAGCCAGATGATCATAGA
Seq A exon
ACTCCAAGCAGTTCCAGCAAACAGAGTTGCAAGCTTACATTTAGTGAGAACAGGCCTACATCAGCTGCTTCTCCAGTGAATATTCTCTTGCCATCGCAGTCTATCTTTGACACCTTCATTAAAGAGGTCTTAAAATGGAAATACCAAATGTTTTTGAACTTTGATAAGTGTGGTGCTCCAACAAGTCTCTGTCAGTCTATCTCAAGACCTGTGCCTGTCCGATTTCAAGATTGTGCAGAATATTTTAATGTTTTTCTACCTTTGATTATATTGAATGCTTTTGAAACA
Seq C2 exon
GTGGCACAGGAATGGCTGAGCTCTCCAAATAAAGAGAATTTCTATCAGTTGCAATTACGAAAATTTCCAGCTGACTATAAAAAATACTGGGAGTTTCTGA
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000043535_MULTIEX2-1/4=C1-2
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.429 A=0.429 C2=0.000
Domain overlap (PFAM):
C1:
NO
A:
NO
C2:
NO
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Rat
(rn6)
No conservation detected
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GTGACCACGGGAAGACTGTTG
R:
TTCTCTTTATTTGGAGAGCTCAGCC
Band lengths:
292-580
Functional annotations
There are 1 annotated functions for this event
PMID: 16524884
Encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: mutation analysis, two hybrid. ELM ID: ELMI002787; ELM sequence: QVIIISDSDDDDDE; Overlap: FULL
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types