MmuEX6100061 @ mm9
Exon Skipping
Gene
ENSMUSG00000043535 | Setx
Description
senataxin [Source:MGI Symbol;Acc:MGI:2443480]
Coordinates
chr2:28999698-29005627:+
Coord C1 exon
chr2:28999698-28999785
Coord A exon
chr2:29000123-29004241
Coord C2 exon
chr2:29005528-29005627
Length
4119 bp
Sequences
Splice sites
3' ss Seq
TTTATCATTTTTCCATTTAGGAT
3' ss Score
11.58
5' ss Seq
ACAGTAAGT
5' ss Score
9.49
Exon sequences
Seq C1 exon
GACCAAGTTAGAACCGGAGCCACATTTTGATGATATGGTGACGTGCAGCCAGATTGTTTATAACTTTAATCCTGAAAAGACCAAAAAG
Seq A exon
GATTCTGGGTGGAGATCAGCCATTTGTCCAGATTATTGTCCAAACATGTATGAAGAAATGGAAACATTAGCCAATGTACTTCAGTCAGATATTGGTCAAGATATGCGTGTTCATAACAGCACCTTTCTGTGGTTCATACCTTTTGTTCAGTCACTCATGGATCTTAAGGATTTGGGTGTGGCTTACATAGTAGAAGTTATTCATCATCTATACTCAGAAGTCAAAGATGTCCTCAACCAGACAGATGCTGTGTGTGACAAAGTCACTGAATTTTTTATTCTGATTTTAATATCAGTGATTGAGCTGCATAGAAATAAAAAATGCTTGCATCTGCTGTGGGTGAGTTCTCAGCAGTGGGTAGAAGCTGTTGTGAAGTGTGCCAAGCTTCCTACTACCGCATTTGTCCGGAGTTGTGAGAAGTCACCTGGAAGTACCTCCAGAGGAGCAGCAATAATGTCGTCCTTGGCGTTGCATTCGGTGCAGTCTAACTCTGTCCAGCTTGCTTGTGTACAGTTGATTAGAGGTCTCCTCAAAGAAGGTTATCAGCTTGGTCAGCAAACACTTTGTAAGCGGTTCTGGGATAAGCTTAACTTATTCCTTCGAGGAAATTTGTCTCTGGGTTGGCAATTGACTGGTCAAGAAACCCATGAGTTACAAATGTGTTTGAAACAAATAATTAGAAACATAAAATTCAAAATGCCCCAATATAGCACTTTTGGGGATTCAACTTCTACATTTAAAACCCCTCCATCTTTTAAAGAAGAAAGTGATAAAATAGACAGGAAGCATAAAAAAAACATTTATTGTTTGGAAAATTGCAGTCCAGTGTCTTCTAAAGAGCCAATGAAAGCTGACACCCATCGAGTATTGATGAAAGTAAATACTACAGAAGAGGAGAACTTCAAGCAGCATTACATTGATTTGAATGAAGAAGAGCAAGAGCCTCTTCCAGCTGAGTTGTGCTTGAAGCAGAAAAGTGAGGCCCTTTTTTCTGAAAGTGCTCAAGAGCAAGTTAAAATTAGCGCAGAGAAGTCTGGGAAAGAAAGCTCTTCATATGCACCATCAAATAGTACTTCAAGAAATGGTCCAGAATGGGGATGTGACAGAGGAGTGATAATGTCAGCACATTCATTGACTGATTCTAGCAGTGATTTTATGGAACAGGTATCTACATCAAATGAAGATGTCTCATTAAAGGATGGCTCTGTTGGTAAAACTTCAAAACCAAGTTTCAAATTACAGAAAGATGAAATTTGTGCAAAGTTATCACATGTCATAAAGAAGCAAATCAGGAAAAGTACTTTGGTAGATAATATTATCGATCTAGAGGAAAATACAGCTATATCTGACCTTGAGAACTGTTCAGGAACAGATGGAGGAGCTCTAAAGGAAGATAGTATTGGACACAATGTCCCTTCAGACCCTGTTCTGGATGACAAGCATGAAGAGCAAAAATCTCAAAACAGTTCATTATTCAAGAAAGAGATAAAGAGTGAGGAGTTGGATAATAGTAGTTCTGATGATGAAGACAAGCTTCAAATCCAGGAAGGCCGTGCTGACGATGATTTGGTATCATTTACAGAAGTTACTGATACACTGGTGAAAGCTCCATGTGAGGGTCATGTAAAGATGGTAGTTGAATCAAGAGATAAGGAAATGAGAGAGAGTACAGCGTTGACTTCTAACTTGGTAGAAGGACAGGTGCCTCATGACAGTAGCAAGCCTTTGGTTGCAGGTCGTCAAATAGACCTCTGTAACATAACTTTAATATCTCAAACCACTGTTATTCAATTTCCATCAGGTTTAAGTAAACAGAATTCATTTCAGCTACAAAAAGGTGATAAAAGATGTTTGACAGCTAACCAAAACAGTGCTGCCACCTGCCGTGGACAAGTTATTGTGATTTCAGATTCTGACGAAGAAGAGGATGAGGATGAAGATGAAAGAAGTAGTAGTGAGGAAAACATCAAACAGAGTAAAGCATGCATAGGGAAAGACTGCTCAGAGCATCGTAGCTTGGCAGTTAATGCCAGTGTGGAGAAGCAGCTTGTAAAAGAGGAAGAAAGGTACCCTGTAGAATTTGAAGACTCTGAATCTCAGGTTTTTGAGTTTGAAAGCTCATCTGAAGTCTTTTCAGTTTGGCAAGATCATAAAATAGACAGCAAAAACTCCCTTCAAGGGGAACAGAAGAGCTATGTAACTCATGTAGCTGATAGTACAAACAATAACTTGGGTTGTGGTGACTCTGTGTCTGAAGAGGTTGTTAGAAACAAAGCAGAGGGAGTTAAAGAGCATGCAGGACCACATAGTAGTGTTTCTGCTGAGGAATTTTGTAAAACTGGAGTAAAAAAACCTAAGAGGAAACGCTATGACAAAGTTACAGCTGAAGATCCTCAGAGGCCTTCCTCTTCTGTTGGAACTGATCAATTGCCTGATCGCAGAGATCTTACTGAAAGTGATTTAAAGAGTGCAGACATGGGGATGGCAACTCCCAGTTCAAGTGTTGAGAGAGATTCTACAATTTTACAGAAGTCTACAAAATCTCGAACTCACTCAAAACCTGTTAGGAAAGTTCCAGCCTCTAAGGCAACTAAGAAAACACATTCAGACACCAGAAGAGGACAGTCTAAGAGTTCATGTTACATAAGTTGTAGAACTTCTCCTGCTATTGTGCCACCAAAGAAGCTTCGTCAGTGTCCAGAGCCAACTTCAACAGTTGAAAAACTTGGTCTGAAAAAAGCCCCTAGGAAGGCATTTGAGTTGTCCCAGAGGTCTCTGGAGTGTATAGTCCAATTACGTGACCACGGGAAGACTGTTGGAGTAGTTGACGCCCCCAAGAAAGCTAAATTAATTTCTCCTCAGACTCTTTCTATCAAAAATAATAAGAAGCTTCTGACAAGCCAGGATCTTCAATTTCAAAGGCTTATGAGATCCAGATCACATAAAAAACGAGACTTTGATTACAAAAATACTGATACTGTAAGAGTGTCACGCATAGTACAGGGATCAGATGTACTTGAAGCAGACTCTGATGAGCCAGATGATCATAGAGTAAGTGAGCCACTTGCCATCAGTAATGAAAAACAGTTAGCAAAATGCATGCTTTCCAAAACAGAAGTGGCAGAAGCCTCTTCTGATCCTTGGGTGACAGGTATAACTTGTCTTGTGAACCAGTGTGAATCTAGAGTGTTAAGTGGAGGAGTGCCAACAGATGTGGTGATGGTCTCTGCTTCAGAGGACCCTGTGGATGGAGGTGCTGTCACAGTTCAAGTTGGGGAGGTGGCATCTGTGAAAGCTGCAGAGCCAGCGTCTAGTAGTGATACAGATGATGATGACAACTTATTCCTAACACAACATGATCCTCAAGATATGGATCTGTGCTCACAGTTGGAAAATAAAACCATTATCGTGGCTCATAAAAAAGATACAGTTCAGAGAGAAGATTCTTTAAGTCGGCCTCAGTTGGAGTCTTTGAGTATCACAAAGTGTAAATACAAAGACTGTGTCGAAACTACAAAAAACCAGGGTGAATACTGCCCAAGACACTCTGAAGCTAAAGCAGCAGATGACGGCCTGTTCCGTAAACCTGGCTTGCCTCTTTCTGTAGCCAGGCCCTTGAGACCTACTACTACCAAGATATTTAGCTCAAGCAGCGCTTCACGAACTGCCAATCTTTCCAAGTCTTTGGAAAGTACTACACTTCAGCAGTCAGCACTAAAAAATAAGTCAAGTGGAGCGCAGCCTAATTTGAAGGTGACACCACCCTCTTCCATGGGTTCTCAGAAGCCAGTGGCTGAGGTGAAAAGTCTATGCAATATTTTTCATTTTCAGACTCCAAGCAGTTCCAGCAAACAGAGTTGCAAGCTTACATTTAGTGAGAACAGGCCTACATCAGCTGCTTCTCCAGTGAATATTCTCTTGCCATCGCAGTCTATCTTTGACACCTTCATTAAAGAGGTCTTAAAATGGAAATACCAAATGTTTTTGAACTTTGATAAGTGTGGTGCTCCAACAAGTCTCTGTCAGTCTATCTCAAGACCTGTGCCTGTCCGATTTCAAGATTGTGCAGAATATTTTAATGTTTTTCTACCTTTGATTATATTGAATGCTTTTGAAACA
Seq C2 exon
GTGGCACAGGAATGGCTGAGCTCTCCAAATAAAGAGAATTTCTATCAGTTGCAATTACGAAAATTTCCAGCTGACTATAAAAAATACTGGGAGTTTCTGA
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000043535-'20-17,'20-15,22-17=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.429 C2=0.000
Domain overlap (PFAM):
C1:
NO
A:
NO
C2:
NO
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 1 annotated functions for this event
PMID: 16524884
Encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: mutation analysis, two hybrid. ELM ID: ELMI002787; ELM sequence: QVIIISDSDDDDDE; Overlap: FULL
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
Other AS DBs: