RnoEX6016198 @ rn6
Exon Skipping
Gene
ENSRNOG00000013491 | Setx
Description
senataxin [Source:RGD Symbol;Acc:1565575]
Coordinates
chr3:7698236-7704312:+
Coord C1 exon
chr3:7698236-7698323
Coord A exon
chr3:7698710-7702831
Coord C2 exon
chr3:7704213-7704312
Length
4122 bp
Sequences
Splice sites
3' ss Seq
ATTGATCATTTTCATTTTAGGAT
3' ss Score
9.31
5' ss Seq
ACAGTAAGT
5' ss Score
9.49
Exon sequences
Seq C1 exon
GACCAAATTAGAACCGGAGCCACATTTTGATGATATGGTGACGTGCAGCCAGATTGTGTATAACTATAATCCTGAAAAGACCAAAAAG
Seq A exon
GATTCTGGGTGGAGATCAGCCATTTGTCCAGATTATTGTCCAAACATGTATGAAGAAATGGAAACGTTAGCCAATGTACTTCAGTCAGATATTGGTCAAGATATGCGTGTTCATAACAGCACCTTTCTGTGGTTCATACCTTTTGTTCAGTCACTCATGGATCTTAAGGATTTGGGTGTGGCTTACATAGTAGAAGTAATTCATCATCTATACTCAGAAGTCAAAGATGTCCTCAACCAGACAGATGCTGTGTGTGACAAAGTCACTGAATTTTTTATTCTGATTTTAGTATCAGTGATTGAACTGCATAGAAATAAAAAATGCTTGCATCTGCTGTGGGTGAGTTCTCAGCAGTGGGTAGATGCTGTTGTGAAGTGTGCCAAGCTTCCTACCACCGCATTTGTACGGAGTTGTGAGAAGTCACCTGGAAGTACCCCCAGAGGAGCAGCAATAATGTCGTCCTTGGCGTTGCATTCAGTGCCATCGAACTCTGTCCAGCTTGCGTGTGTACAGTTGATTAGGGGTCTCCTCAAAGAAGGTTATCAGCTTGGTCAGCAAACACTTTGTAAGCGGTTCTGGGATAAACTTAACTTATTCTTACGAGGAAATTCGTCTCTGGGTTGGCAGTTGACTGGTCAAGAAACCCATGAGTTACAAATGTGTTTGAAACAAATAATTAGAAACATAAAAATCAAAATGCCCCAATATAGCACTTTTGGGGATACAACTTCTACATTCAAAACCCCTCCATCTTTTAAAGAAGAAAGTGAACAAATAGACAGGAAGCCTAAAAAAGACATTCATTCCTTGGGAAATTGCAGCCCAATACCTTCTAAAGAGCCAATGAAAGCTGACAGCCATCGAGTGCCGACGAAAGCAAGTGCTACAGAAGAGGAGGACTTCACGCAGCACTATATTGACTTGAATGAAGAAGAGCCTCTGCCGGCCGAGCTGGGCGTGAAGCAGAAAAGTGAGGCTCTTCTTTCTGAAAGTGCTCCAGAGCAAGTTAAAATAAGCACAGAAAAGTCTGGAAAAGAAAACTCTTCATATACAGCACCAAATAGTACTTCAAGAAGTGGTCCAGAATGGGGGTGTGACAGAGGAGTAATTATATCAACACATTCATTGACTGATTCTAGCAGCGATTTTCTGGAAAAGGTATCTACATCAAATGGAGATGTCCCATTAAAGGATGGCACTGTTGGTAAAACTTCAAAACCAAATTTCAAAGTACAGAAAGATGAAATTTGTGCAAAGTTATCACATGTCCTAAAGAAGCAACACAGGAAAAGTACTTTGGTCAATAACATTATTGATTTAGAGGAAAATGCAGCCACGTCTGACCTTGAGAACTGTTCAGGAACAGATAGAGGAGCTCTAAAAAAAGATACCATCGAACATGATGTGTCTTCAGACTCTGTTCTGAATGATGACCATGAAGAGCAAAAATCTAAAAACAGTTCGTTGTTCAAGAAAGAGATAAAAAGTGAGAAGTTGGATAATAGTTCTTTTGATGATGAAGACAAGCTTCAAATCCAGGAAGGCCATGCTGATGATGATTTGATATCATTTACAGAAGTTACTGATACACTGGTGAAGAAAACTCCATGCGAGGGTTCTGTAAAGGTGGCAGTTGAATCAAGAGATAATGAGATGAGAGTGCTGACTTCTAACTTGGAAGGACAGGTGCCTCATGACAGCAACAAGGCTTTGGTAGCAGGTCCTCAGGTAGACCTTTGCAACATAACTTTAATATCTCAAACCACTGTTATTCAATTTCCCTCAGGTTTAAGTAAACAGAATTCATTTCAGCTACAGAAAGATGATAAAAAATGTTTGACAGCTAACCACAACAGAGATGCCACCTGCCATGAACAAGTTATTATTATTTCAGATTCTGATGATGAAGATGATGCTGATGAGCAAGATGAGGATAAACGTTGTGGTATTGAGGGAAACATCGAACAGAGCAAAGTGTCCAGGGAGAATGACTGTTCAGAGCAGCATGATTTGGTAGTTAACACCAGTGTGGAAAAGAAGCTTGTGAAGGAAGAAGAAACAAATTGTCCTATAGAATTTGAGGACTCTGAATCTCAGGTTTTTGAGTTTGAAAGTTCATCTGAAGTCTTTTCAGTTTGGCAAGATCATAAAATAGACAGCAAAAGTTCCCTTCAAGAGGATCAAAAGAGCTGTATAGCTCATGTAGCTGATAGTACAAACAATAACTTAGGTTGTGGTGCAGATTCTGTGTCTGAAGAGGTTGTTAGAAACAAAGAAAAGGGTGTTAAAGAGCATGCAGAACCACACAGTAGTGTTTCTGCTGAGGGATTTTGTAAAATTGGAGTAAGAAAACCTAAGAGGAAACGATGTGATAAAGTTACAGCTGAAGATCCTCAGCGGCCTTCATCTTCTGTCAGAACTGAACAATTGGCTGAGCACAGAGATCTTCCTGAAAGGGACTTAGAGAGCGCAGATGTGGACATGGCAGCTCCCAGTTCTAGTGTTGAGAGAGATTCTACGGTTTTACAGAAGAAGTCTACAAAGCCTCGCCCTCACTCAAAACCTGTTAGGAAAGTTCCAGCTTCAAAGGCTACTAAGAAAACCCATCCAGATACCAGAAGAGGACAGACTAAGAGTTCATGTTATATAAGTTGTAGAACTTCTCCTGCTATTGTACCACCAAAGAAGTTTCGCCAGTGTCCAGAGCCAACTTCGACAGTTGAAAAACTTGGTCTGAAAAAAGGTCCTCGGAAAGCATTTGAGTTGTCCCAGCGGTCTCTGGAGTGTATAGTCCAATTACGTGACCACGGCAAGACTGTTGGAGTAGTTGAAGCCCCCAAAAAGACTAAATTAATTTCTCCTCAGACTCTCTCTATCAAAAATAATAAGAAGCTTCTGACAAGCCAGGATCTTCAATTTCAAAGGCTTATGAGATCCAGATCACACCAAAAACGAGACTTTGATTACAAAAATACTGATAGCGTAAGAGCAGTGTCACGCGTAGTGCAGGGTTCGGATGTACTTGCAGCAGACTCTGATGAGCCGGATAATCCTGGAGGAAGTGAGCCGCTTGCCATCAGCAGTGAAAAGCAGTTAGCGAAAGGCACGCTTTCCAAAGCAGAAGTGGCAGAAGCTGCTTCTGGTCCTTGGGGAACAGGTATAACTTGTCTTGTGAACCAGTGTGAATCTCGAGTGTTAAGTGGAGGAGTGCCAACAGATGTGCTGATGGGCTCTGCTTCAGAGGACCCTGTGGGTGGAGGTGCTCTCACAGTGCAGGTTGGGGAGGTGGCAGCAGTGAGAGCTGCAGAGCCAGAGTCCAGTAGTGATACAGATGATGATGACAATTTATTCCTAACACAACATGACCCTCAAGATATGGATCTGTGCTCACAGTTGGAAAATTCTAAAGCCATTATTGTGGCTCATAAAGATACAGTTCAGAGAGAAGACTCTCTAAGTCGGCCTCAGTTGGAGTCTTTGAGTATCATAAAGTGTAAATACAAAGACTGTGTTGAAACCACAAAAAACCAGGGTGAATACTGCCCAAAACATTCTGAAGCTAAAGCGGCAGATGACGACGTGTTTCGTAAACCTGGCTTGCCACTTTCTGTAGCCAGGTCCTCGAGACCTACTACTACCAAGATATTTAGCTCAAGCAGTGCTTCACGAACTGCCAATCTTTCCAAGTCTTTGGAAAGTACCACACTTCAGTCAGCACTGAAAAATAAGTCAAGTGGAGCACAGTCTAATTTGAAGATGACACCATCCTCTTCCCTGGGGTCTCAGAAGCCAGTGGCTGAGGTGAAAAGTTTATGCAATATTTTCCATTTTCAGACTCCGAGCAGTTCCAGCAAACAGAGTTACAAGTTTACCTTTAGTGAGAACAGGCCTGCGTCGGCTGCTTCTTCAGTGGACATTCTCTTGCCATCCCAGTCTATCTTTGACACCTTCATTAAAGAGGTCTTAAAATGGAAATACCAAATGTTTTTGAACTTTGATAAGTGTGGTGCTCCAACAAGTCTCTGTCAGTCTATCTCAAGACCTGTGCCTGTCCGATTTCAAGATTGTGCAGAATATTTTAATGTTTTTCTACCTTTGATAATATTGAATGCTTTTGAAACA
Seq C2 exon
GTGGCACAGGAATGGCTGAACTCTCCAAATAAAGAGAATTTCTATCAGTTGCATTTACGAAAATTTCCAGCCGACTATAAAAAATATTGGGAATTTCTGA
VastDB Features
Vast-tools module Information
Secondary ID
ENSRNOG00000013491-'9-10,'9-9,10-10=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.458 C2=0.000
Domain overlap (PFAM):
C1:
NO
A:
NO
C2:
NO
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Human
(hg19)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 1 annotated functions for this event
PMID: 16524884
Encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: mutation analysis, two hybrid. ELM ID: ELMI002787; ELM sequence: QVIIISDSDDDDDE; Overlap: FULL
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]