DreEX6082829 @ danRer10
Exon Skipping
Gene
ENSDARG00000022996 | setx
Description
senataxin [Source:ZFIN;Acc:ZDB-GENE-070402-1]
Coordinates
chr21:3787583-3791573:+
Coord C1 exon
chr21:3787583-3787676
Coord A exon
chr21:3787804-3791331
Coord C2 exon
chr21:3791477-3791573
Length
3528 bp
Sequences
Splice sites
3' ss Seq
TCCTAATCTTCGTCTTGTAGGCA
3' ss Score
8.5
5' ss Seq
GAGGTGGGA
5' ss Score
4.3
Exon sequences
Seq C1 exon
GAGGATGGTAAAAGTAGAGCCAGAATATGACGACAATGTCGTGACTTGCAGTCAGATGGTGTATGACTGTTATGCCTCGAAAAAACAAGGCCAT
Seq A exon
GCACCTGGCTCATCCAACAGTGGTGTTGGCAGCAACTATGTGATTTATGACGATATGCAATCACTGGTCAGCGTGCTTAATTCAGAGATGGGCCAGAGCATGCGTGTATATGGATGCACTTTTCTGTGGTTCATCCCATTTGTTCGTTCCATAATGGAACTTCAAGAGCACAATGCTTCCTATATTAGTGAAATCATCCACTATCTTTGTGATAAGATCCGAGATAATCGGTACATGCTGACTGGACAAGCAAGCGTGTGTGATAAAGTGACTGAGCTCTTTGCTCGTATCTTTATTCAAATCGTTGAGCTACACTATACCGAAGGACAAATGGGAATACTTTCTCGCTGTCCCCCCAAGTGGGTTGAGGTGATTGTCATGTGCGTCGTCTTATGTGATGAACCTTATGGACCCCCAGACAGGATGGGTGGGATTCACAGTGTCAGTTCAACATCTTACAGTCTTGGCATTGTAGGAAGACCTACATCAGAATGTGGGAATGGAGCAATAATTAAAGGCTGTTTGACGCTTATTCGGCAGCTGCTTAAGGAAGGGAAAAGAAGATCTGACCCAGATGCGGCCATGTTTTTGAATTTGCTTAACAAGCAGCTGCGTGGTGATACCAACAAAAGGTGGAGTCTAACTTTTTCAAATTCTGCAAAGCTTCAGCAGTGTTTGAGGAAAATTGTGCAGCTGATGGCTGAAAGACCTGCTGTTCCACCCCGATCCGCACCATCTGTTGAGGCAGCTACAAATACTGTTGTTTCCAGAAATTCAGTATCAATCTGCCAACAACAAGAGGACCCGGAGGCAGGTCCCAGCAGAGCTGCGTTTATCAAAGAGGAGCCTCTTTGGAATTATGGAAAAAAATCTTTCTCCAATGAGGAATTCTCATGTGGGCCTGAGGATGTCTTCAAGGGTAAAAAGGAACCTTCTGACCCAGTGTTAATTTCAGAGCTGAGGCCTGCTGTTGAGTTGACCAATATAAAACCAGATCTGGGTAAACTGCAGGAAATTCGATCAAGATTAAATGATGATCAGAGTTTGTCAAAGATCGAAGCAATTGCAAGGAAGAAGTCTGACGTGTCAGCTAAAAAGAGACCAGGTTTTGGGGCTTTAAAAAATGAGGAGGAGGAGGAGGATGATGATGATGATGATGATGATGATGAACCCCTTCATATCACTCGAACTCGTCTGATAAAATCTGCAATCCACAAGCTTGAATCTAGTGACTCTGACGTTGACTCCAGAGCAACTGCGTCTTCGGTTATTTCCAAGCAGAACACAGAGTCCACTACCATAGTTATCTCTGATGATGAAGATTCTGATAATGATATAAGGCCAAATGACCCCTTGAGGTCTAGTTACAAAGAATGCACAGTAAAAAACAAATCTCCAGAAAGTCCTGTAATGCCTGAGAGTCCGGGGCGTGATTATGATGATCTAAGTGAATCACAAGTGTTTGAGTTTGAGACTCAGCAATATGTGGCATCTGCTTGGGATAATGCAGATTTGGATGGATCAGTCTTGACAAAGAATCTCAAATCAGATCGAATACTCAAGCCACAGTTGGATGAAACGCCTAATGAAGCATCTCCCTCATGGAGTTCAGAGACTGAGCTGGTACCAGATGAGGACATTGAGAGGGCCTGTCAGCAGGCAGAAGAGAAGATCAGACAACAGCAGCCGAGAAAGCCAGCAGATGAGATGGAAAGAGACTATAAGCAGGTGGAAGAGAAAATCAGACCACAGCAGACACGAGAGAATTCGGATGTGCATGAATTCTCATCCAAAGCATCAAGTACTACAAAAAGCTGGGATAAATTTGCCAAACCAAAACCTCTAAAGACTAAAGTAACAAAAACCACTCCATCTGATAAGAGAGACCATTTGCAGGTTAAAAAGCCAGTGTTAATTGATGCCCTTGCTCAAAAAATCAGACGCCACCCTTGGAAACGTAGCTCAACATCTGAGGACATGGAGGAACCTTCCTCTTCAACTACTCCATCCTCATCTGCTGTATCCTCCACCTCCTCCTCCTCCTCATCATCATCATCCACTCCATCCTCCAGCTCCATCACTTCTCCTTATTTTTCTGCATCTACGTCACGTGGCACCCCTGCCATTGTTCCTCCAAAGAAGGTGCGTAAAATTGCTGAGCCAGAATCAACGGCAGAGCGTTTAGGATTGAAAAAGAAGGAAAGGAAAGCCTTTGATCTTTCTCAGCGTTCACTTGACTGTGTCGCCAGACTCAGGTGCCATGGCCAGAACGTGCAGGTGGAGCCACATCAGAAAAGAAGGCGAGCGTCTCGAACCAGTAAGACTTCTCCGCAGAAACGTATGGTGAAAGCTAACAAGAAACTAATGGGATCTCAAGATATTCAGTTTTTCAGGCAAAGTCGTGAGAAGCATCAGAAGCCAGCAACAGAACCCATTACAACATCAGCTTCCAAACCAGTCAGTCGGCAAGATGAATTGCACTCATCGAGACCAACAATTCCAAACAATGAGGATGGTGACTTCTTGCCCTGTCCTCAACCAGATGCCCATTGTCAGCAGGATAATGAAAAAGGTGCATTAGGGAGTAGCGATTCTAGTGGGGATGGGGTAGGGAATAAGTTCCTCCAAGCTAGTGAGGCTGCTGAAGGTAACTTGGAAGGAGAGAAAGCTGCTCAAGCATCAAAAGAGGATGTTGATGATGAATGGATGTTCTATACACAGATGGAACCTACAGACATGGAAATCTGTTCACAAATGGAGGAATTTGAGGATGAAAACGACGAACTCTTTCTTACCCAGAGAGATCCTGTTGACATGGACATCGATACAGATAGTGGGTCGGATACCCCTGGTCAACCTGACTTCACTGACAAAAATGTACCGCCTTCTAATGCGGCAAATGATCATTTGTTCTTGAAGCCTGGAATGTCACCCATGTCTCAGAAAAAAGCCAAACCTTCCACCACTAAAATATACACTCCCAGCTCCCGTAGTGCCTCACTTGTCCTTGAAATGGAAAAAGGAGCCAAGCCTCCCCCTCCTGCAAATGTCGCTAAAGCAAAAATTCCTCGATTGGCTTCAGCAATGCCACCCCCAGCAATGCCACCACCAAAAATGCCACCCCCCAAAATGTTCCAGCCTTTACCCCCTCCACAATTACCAAAGCCACCTGCCTTAAAACAAGTAACTCTTCCTCAGGGCAGTGTCCCCAAGTTGGTCACCAGTAATAAAATAAGCTCAACCTCAGAACCCCCATCATACAAGGTATACCAAAGACCAGAGGCTCCAGTTAACAAGCCAGTTAACAAACCAATGCCCACAATGGATCAAAGCCCAAAGTTTGACCTTTCGGTGTTAACCCAGGCAATCCTTAAATGGGAATACAGAATGCTTGATAATTATAAAGCATTTGGGAGTCCACTTGATCTGTGCCAACTGCCGCTGAAGGAGGTGCCAGTAAATTTTTCTTCCTACCTGGAGTACTTCAACACCTTGTACCCACTGCTGCTAATTAATGCATTCGAAGAG
Seq C2 exon
ATGGCTAATGAATGGCTCAAAGAGGGAAGGGTCAAGCTGTACCTAAAAGTCCAAGGTATTGAATACAGCAATCGCACTGCTAGTGCTAGCTTCATTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSDARG00000022996-'11-10,'11-9,12-10=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.668 C2=0.000
Domain overlap (PFAM):
C1:
PF127262=SEN1_N=FE(6.8=100)
A:
PF127262=SEN1_N=PD(25.2=9.7)
C2:
NO
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 1 annotated functions for this event
PMID: 16524884
Encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: mutation analysis, two hybrid. ELM ID: ELMI002787; ELM sequence: QVIIISDSDDDDDE; Overlap: FULL
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]