MmuEX6101110 @ mm9
Exon Skipping
Gene
ENSMUSG00000026872 | Zeb2
Description
zinc finger E-box binding homeobox 2 [Source:MGI Symbol;Acc:MGI:1344407]
Coordinates
chr2:44849999-44854512:-
Coord C1 exon
chr2:44854404-44854512
Coord A exon
chr2:44851546-44853515
Coord C2 exon
chr2:44849999-44850179
Length
1970 bp
Sequences
Splice sites
3' ss Seq
AATTTTAATTATCCTTTCAGGTG
3' ss Score
9.23
5' ss Seq
CAGGTAATG
5' ss Score
9.43
Exon sequences
Seq C1 exon
CACCAAATGCTAACCCAAGGAGCAGGTAACCGCAAGTTCAAGTGCACGGAGTGTGGCAAGGCCTTCAAGTACAAGCACCACCTGAAAGAACACCTGAGAATTCACAGTG
Seq A exon
GTGAAAAACCTTACGAATGCCCAAACTGCAAGAAACGCTTCTCTCATTCTGGGTCCTACAGTTCACATATCAGCAGCAAGAAATGTATTGGTTTAATATCAGTAAATGGCCGAATGAGAAACAATATCAAGACGGGTTCTTCCCCTAATTCTGTTTCTTCTTCTCCTACTAACTCAGCCATTACTCAGTTAAGGAACAAGTTGGAAAATGGAAAACCACTTAGCATGTCTGAGCAGACAGGCTTACTTAAGATTAAAACAGAACCACTAGACTTCAATGACTATAAAGTTCTTATGGCAACACATGGGTTTAGTGGCAGCAGTCCCTTTATGAACGGTGGGCTTGGAGCCACCAGCCCTTTAGGTGTACACCCATCTGCTCAGAGTCCAATGCAGCACTTAGGTGTAGGGATGGAAGCCCCTTTACTTGGATTTCCCACTATGAATAGTAACTTGAGTGAGGTACAAAAGGTTCTACAGATTGTGGACAATACGGTTTCTAGGCAAAAGATGGACTGCAAGACGGAAGACATTTCAAAGTTGAAAGGTTATCACATGAAGGATCCATGTTCTCAGCCAGAAGAACAAGGGGTAACTTCTCCCAATATTCCCCCTGTCGGTCTTCCAGTAGTGAGTCATAACGGTGCCACTAAAAGTATTATTGACTATACCTTAGAGAAAGTCAATGAAGCCAAAGCTTGCCTCCAGAGCTTGACCACCGACTCAAGGAGACAGATCAGTAACATAAAGAAAGAGAAGTTGCGTACTTTGATAGATTTGGTCACTGATGATAAAATGATTGAGAACCACAGCATATCCACTCCATTTTCATGCCAGTTCTGTAAAGAAAGCTTCCCGGGCCCTATTCCCCTGCATCAGCATGAACGATACCTGTGTAAGATGAATGAAGAGATCAAGGCAGTCCTGCAACCTCATGAAAACATAGTCCCCAACAAAGCTGGAGTTTTTGTTGATAATAAAGCCCTCCTCTTGTCATCTGTACTTTCCGAGAAAGGACTGACAAGCCCCATCAACCCATACAAGGACCACATGTCTGTACTGAAAGCATACTATGCTATGAACATGGAGCCCAACTCTGATGAACTGCTGAAAATCTCCATTGCTGTGGGCCTTCCTCAGGAATTTGTGAAGGAATGGTTTGAGCAAAGAAAAGTCTACCAGTATTCGAATTCCAGGTCACCATCACTGGAAAGGACCTCCAAGCCGTTAGCTCCCAACAGTAACCCCACCACAAAAGACTCTTTGTTACCCAGGTCTCCTGTAAAACCTATGGACTCCATCACATCGCCATCTATAGCAGAACTCCACAACAGTGTTACGAGTTGTGATCCTCCTCTCAGGCTAACAAAATCTTCCCATTTCACCAATATTAAAGCAGTTGATAAACTGGACCACTCGAGGAGTAATACTCCTTCTCCTTTAAATCTTTCCTCCACATCTTCTAAAAACTCCCACAGTAGCTCGTACACTCCAAATAGCTTCTCTTCCGAGGAGCTGCAGGCTGAGCCGTTGGACCTGTCATTACCAAAACAAATGAGAGAACCCAAAGGTATTATAGCCACAAAGAACAAAACAAAAGCTACTAGCATAAACTTAGACCACAACAGTGTTTCTTCATCGTCTGAGAATTCAGATGAGCCTCTGAATTTGACTTTTATCAAGAAAGAGTTTTCAAATTCTAATAACCTGGACAATAAAAGCAACAACCCTGTGTTCGGCATGAACCCATTTAGTGCCAAGCCTTTATACACCCCTCTTCCACCACAGAGCGCATTTCCCCCTGCCACTTTCATGCCACCAGTCCAGACCAGCATCCCCGGGCTACGACCATACCCAGGACTGGATCAGATGAGCTTCCTACCGCATATGGCCTATACCTACCCAACGGGAGCAGCTACCTTTGCTGATATGCAGCAAAGGAGGAAATACCAGAGGAAACAAGGATTTCAG
Seq C2 exon
GGAGACTTGCTGGATGGAGCACAAGACTACATGTCAGGCCTAGATGACATGACAGACTCCGATTCCTGTCTGTCTCGAAAGAAGATAAAGAAGACAGAAAGTGGCATGTATGCATGTGACTTATGTGACAAGACATTCCAGAAAAGCAGTTCCCTTCTGCGACATAAATACGAACACACAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000026872-'19-23,'19-22,20-23=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.189 A=0.483 C2=0.123
Domain overlap (PFAM):
C1:
PF056057=zf-Di19=PD(1.6=2.7),PF0009621=zf-C2H2=WD(100=62.2)
A:
PF134651=zf-H2C2_2=PD(57.7=2.3),PF0004624=Homeobox=WD(100=7.8)
C2:
PF134651=zf-H2C2_2=PU(38.5=16.4)
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CCAAATGCTAACCCAAGGAGCA
R:
TGTGTGTTCGTATTTATGTCGCA
Band lengths:
287-2257
Functional annotations
There are 3 annotated functions for this event
PMID: 12714599
Encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: alanine scanning. ELM ID: ELMI000260; ELM sequence: PLNLS; Overlap: FULL
PMID: 12714599
Encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: alanine scanning. ELM ID: ELMI000261; ELM sequence: PLDLS; Overlap: FULL
PMID: 12714599
Encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: alanine scanning. ELM ID: ELMI000262; ELM sequence: PLNLT; Overlap: FULL
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
Other AS DBs: