MmuINT0022335 @ mm10
Intron Retention
Gene
ENSMUSG00000025432 | Avil
Description
advillin [Source:MGI Symbol;Acc:MGI:1333798]
Coordinates
chr10:127011699-127013653:+
Coord C1 exon
chr10:127011699-127011878
Coord A exon
chr10:127011879-127013507
Coord C2 exon
chr10:127013508-127013653
Length
1629 bp
Sequences
Splice sites
5' ss Seq
AAGGTGAGA
5' ss Score
8.68
3' ss Seq
GTTCTCCTCACCCCATTCAGGGG
3' ss Score
7.8
Exon sequences
Seq C1 exon
GGCGGGACTTCCAGGAAGGGAAACGAGGAGCCGGACCCTCCAGTAAGGCTCTTCCAGATCCACGGGAACGACAAATCCAACACCAAAGCAGTGGAGGTCTCGGCCTCTGCTTCCTCGCTCAACTCCAACGACGTCTTTCTGCTGCGGACTCAGGCAGAGCACTACCTGTGGTACGGCAAG
Seq A exon
GTGAGAGTGCTGCTGGGTCCTACTAGTTGGTCAGTTGGGAGTCACGACTGCCCTGGCTCCACCCTCAGCCCTCAGTAATGCAGAAGTACACCCAAGTTCAATCCCCAGAAACACAAAAGTCAGAAAATGGGAACTCCTATCTGTAACCCCAGAGCACACACACACGTAGGTACACTCACATATGCACTTATGTACACACATCTACATACACACACAAACATACCCACACATACACACACACATTTGTACACTCACATACAAACACATACACACATATGTACGCACATCTACGTACACATACACAAAATCCTGGAGCTGGAGAGATGGCTCAACAGAGATGCCACCTGCAGAAGACCTGGGTTCAGGTCCCCCACGGTGGCTCACAACCATTTGTAAACCCCATTCCAGGGGATCTGACACCCTCTTTGACCTCCAGAGGCACTGCACACACTTTGAGCACACACCTACACACACATACATGTGGATAAAACACTCATGCAAGTAAAATAAATCTTTAAAGAGCACCAGTGAACGAAAACTTCCTTACACAAAGATTTGTATACACATGTGCGCAGTAGCAATGTTTATTCACAATCCCCTCAAATTAGATGCGATCTGGAAAAATAGATGAAATTCAAAAATAGTAATATTCCTTCAATGGAATATTACTCAGCACTAAAAATGGAAGGGCCACTCATGCACACAACACAGAGTCTCCAGGTGACAAGAGTCTCCTGAGAACTGAAAGACGGTCTCCCAGGCTGGATGTGACAAGCTTCCACTTGAGAAATGCCAGGAATGTTCTAATGGAGCACAGCTTAGCCTATGTCAAGAGTTCAGGACTCAGGGCTTGACGTCAAAGGGAGAGGAATTGAAGAGGACTAAAGAAATTTCACTGTGGGAACAGAGATCTGTTTAAGCCTTGTGGAACCCAACAGTCAGGTTTACTGTAATTAAAAAAAATAAGACTAGGGGTTGGAGAAATGGCTCAGTGGTTGAGAGCACTGACTGCTCTTCCTAAGTCCTGAGTTCAAATCCCAGCAACCACATAGTGGCTCACAACCACCTGTAATGGGATCTGATGCCCCCTTCTGGTGTGTCTGAAGACAGCTACAGTGTACTTACATATAACAATAAATAAATCTTAAAAAAAAAAAGAAAAAAAAAAAAGACTAAAGCTGGGCGGTAGTGACACACACCTTTAATCTCAGCACTCAGGAGGCAGAGGAGTCTCAGAGTTTGAGAGCATCCTGAGTTCCAGGACAGCTAGTGCTTCACAGAGGAATCCCGTCTCCAAAAAACAAACAAAAACAAAACAAAACAAAAATAATGAAAGTTACATGCTAGGGATACAGGGCTTGCTTGTTACAGAGGCAGAGCCTTTACTGTGCATGTGCATCAGAGGAAACTGTGTGCTAGAATCCAGGTGAGGCTAAATCAGAGACGGCTTCTGCGTCGGCGCACTGTGGGTTTCAGAGCAGGCCTGTCCTTTGCCTGCATGTCCTGTCCTCCCCCCATCCCCCATCCTGGGGCACGGCAGCACAGAGCCAACCCCCAGTTTCAGAAGCCTGGCATCCCTACCAATGTGCCCTGTGCCTCTAACACCTGTGTTCTCCTCACCCCATTCAG
Seq C2 exon
GGGTCTAGTGGGGACGAGCGGGCGATGGCTAAGGAGCTGGTCGACCTTCTCTGTGATGGCAATGCGGACACTGTGGCTGAGGGCCAGGAGCCACCTGAGTTCTGGGACCTTCTGGGAGGAAAAACAGCCTACGCTAATGACAAAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000025432:ENSMUST00000026500:14
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.367 A=NA C2=0.122
Domain overlap (PFAM):
C1:
PF0062617=Gelsolin=PU(48.6=56.7)
A:
NA
C2:
PF0062617=Gelsolin=PD(48.6=69.4)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GGACTTCCAGGAAGGGAAACG
R:
GCGTAGGCTGTTTTTCCTCCC
Band lengths:
310-1939
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Pre-implantation embryo development
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types