MmuINT0042032 @ mm10
Intron Retention
Gene
ENSMUSG00000063681 | Crb1
Description
crumbs family member 1, photoreceptor morphogenesis associated [Source:MGI Symbol;Acc:MGI:2136343]
Coordinates
chr1:139242978-139249075:-
Coord C1 exon
chr1:139248119-139249075
Coord A exon
chr1:139243526-139248118
Coord C2 exon
chr1:139242978-139243525
Length
4593 bp
Sequences
Splice sites
5' ss Seq
AAGGTGAGA
5' ss Score
8.68
3' ss Seq
TCCCTCTTTGGACATTGCAGAGT
3' ss Score
5.46
Exon sequences
Seq C1 exon
GAATTCACTGTGAAGAAGACGTTGATGAATGTTTACTGCACCCTTGCCTAAATGGTGGTACTTGTGAGAACCTGCCTGGGAATTATGCCTGTCACTGTCCCTTTGATGACACTTCTAGGACATTTTATGGAGGAGAAAACTGCTCAGAAATTCTCCTGGGCTGCACTCATCACCAGTGTCTGAACAATGGAAAATGTATCCCTCATTTCCAAAATGGCCAGCATGGATTCACTTGCCAGTGTCTTTCTGGCTATGCGGGGCCCCTGTGTGAAACTGTCACCACACTTTCATTTGGGAGCAATGGCTTCCTATGGGTCACAAGTGGCTCCCATACAGGCATAGGGCCAGAATGTAACATATCCTTGAGGTTTCACACTGTTCAACCAAACGCACTTCTCCTCATCCGAGGCAACAAGGACGTGTCTATGAAGCTGGAGTTGCTGAATGGTTGTGTTCACTTATCAATTGAAGTCTGGAATCAGTTAAAGGTGCTCCTGTCTATTTCTCACAACACCAGTGATGGAGAATGGCATTTCGTGGAGGTAACAATCGCAGAAACTCTAACCCTTGCCCTAGTTGGCGGCTCCTGCAAGGAGAAGTGCACCACCAAGTCTTCTGTTCCAGTTGAGAATCATCAATCAATATGTGCTTTGCAGGACTCTTTTTTGGGTGGCTTACCAATGGGGACAGCCAACAACAGTGTGTCTGTGCTTAACATCTATAATGTGCCGTCCACACCTTCCTTTGTAGGCTGTCTCCAAGACATTAGATTTGATTTGAATCACATTACTCTGGAGAACGTTTCATCTGGCCTGTCATCAAATGTTAAAGCAGGCTGCCTGGGAAAGGACTGGTGTGAAAGTCAACCCTGTCAAAACAGAGGACGCTGCATCAACTTGTGGCAGGGTTATCAGTGTGAATGTGACAGGCCCTATACAGGCTCCAACTGCCTGAAAG
Seq A exon
GTGAGAGGAGTGGGGTGCCCCAGAGTGCTGTGCCTCTGAGCAGAGCCATCTCTAATCACCCAGGGTGCCGTCCCCTGTTAGGAAACATAAGGACCCCTCAGGACTTATGCTGGTATTTGTTCACTAATGAGATAAAATGGCATAGTCATGATATGTATTAATTATGAGTGGGTTTCATAGGATAGCTGAGCTTTTTTGGGCTGAAAAGTAAAATTAATAATAATAACAATAAGCAAATAACTCCAATTAATGTGGTGTTTTATCTAGTTAGCAAAATGCTCTTAGCAATTTGCCATTCATTGTGTATCAGAAATATATAGAAAACTTTAGTTCTTTGTACAAGATGTCATCTTTTAGAGAAAGGGGAGTTTTGGACAGAAAAACTAGTTACTGCCACGTACTAATACCACACCTTGTGCTTGCTAGAGTCTCAGTGAATAAACCCTTTGCTGATCTCTCTGTGTAACTCATACTTCCGTAAGAATCGTGGTTAAGATTAGCATGTTGACAAGCCATCAGTTCTAGTCAAGACTGTCTCCTAAAAGGCCTTGTTTTCTAAAGAGGAGAGATGTCTTCAGTCGGAAAAAGCAAGAAGACATGAACTGTATTATCAGGAAAACTTGGTAGTTGTCACGCACAGATCCGTGATTCCTCTAGTGAATCAGTTTGAAGTGGATTTCCAATCCCTCACTTTTGACATCACTCTGAAGGCTGCCATCAATAGCGATCAATACATACCTGCTCACTTTTATTATTATTATCATGTATTGAGAGGGCTGAAAGGGAACTCTAACAGACTGCTTTGAAGTTCAGCTGCAATTTACTCTAGCATTTTAGAATGAGTCCAAGAAGAACAACATATGGCAAATAGGCTACGCTGTTCCGTATGAAGGAAAATTAAAACCAGCCGTAGCCTATACTCTACTCCATGTTCAATGGCTAAGAATTATTAGAAACTATTCGCAGGTTTTCCCCTAACCACAATATTCATTACAATCATGGACCTGCTTGACAATGAGGCATGGCATCTGCTGCTCCGCGCAATATTTTAAATGGCGTGGCAAGTTGTTTTGTGATTATTTTTAAAGGTGAAATTATGCCGAGGCAATGGTTCACGTTTTGAAGAAAAATCTAATTGACCCAAAGCAATATTTTTACTACATATACAAAATAACAAACAGATGCGGACTAATTTTGACTGGCTTCCAGATGCGGTGACCCTTGAGGTTAGCACTGACCTGGGAATGCTGACTGTCCTAGGAAATAGATTCGAGAGATGCCAAGCCAGCAGGTTCTGGTTTTCTTTACATTTTTTTTTCCAACTTGGAAAATAATGAACTTTTGAAACAAAATTCCTGATTTGGTTACACTTTCCATATTCCCCCAAATAGTGTGATTACACCCCTCCACTCACACCGAGTGTAACTATATCCCCTACCCTTATACAAAGTGTGATTAAATCTTCTATTTTCACAGTTTGAAACTGTTTAGCTCAACATTTGATATCAAATGATTATAGGGCAGGAATTTCATAAAACCCTTCACTTCTGAAAATTTAGGAGGAGAATTTTAAAAGAAAGTTATATTTTTCATGTGACCCTGAGATCATAAAGTTAAAGTATTCTTTATTGCTGAGATCCATAAGGAAATATTTTCTGTATTTTATTCCTTAAACACACACACACACACTTAAGACTCCAAATGAGACTCTATATACATATAGAGCCATTCTATATGCATATTCAGGATGAGGCACACTAAAAATCAAGAGGGGAAGCCATCAAAGTAACAATTTTTTAAAGATGTATTTTATTATTCTATGTGTGTGGGTCTGAGTGTATGCTTCTGCACCAGGTGAGTGGAGATTCCCCTGGAACAGGAGTTAATGACAGTTTTGAGCTGCCTGATGTGGGTATTGGGATCAAACCTTGGTCCTCTACAAGGACAGCTCATACTTTTAACCACTGAGTCACCTCTCCAGTTCTCAAACAATGATTTTGGAACAATGCTTGCCAGTGTTAAACCCAATGAAAGAAGAAGGCATGTTGAATAAAGGGTGGAGTTATCTGAATGATACAAAATGTAGATAGACATTGCCAATATCTTGAAACTGATCTCAAGTCATTTATGCCCCCCATAAGGTTTCTGTAACAACCTGAACTGCCTGCAGTGATAACATTGTATGTCTTGCATTATGTGTTAGAAGAAGGTCTTCTGGGATATTGGTCTAAAGCAGTTGTTCTCAACCTTCCTAATGCTGTGACCCTTTAATATAGCTCCTTGTGTTTTGCTGACCTCCCAACCATACAGTTATTTTGTTGCTACTTCACAACTGTAACTTTTGCTACTTTTGTGAATTATAATATAAATGTCTGTGTTTTCCAATGGTCTTAGACAAGCCCTGTGACAGCCCTGTGTCATTCATCTCCAAAGGCTTACGGCCCACAGGTCCTAAGAGAACATGTAACGTACCTCTTTCTATGTTCGGAAAGTCTCTAATTTAAAAAAAAAAACAATTTATATATGCTTGTCTTCCTTTGTACGCCCAGACTTTTAGAATGCTATTATATTAGAGTCAGTGATAGTTAGGTTTGACAGAGCCTCATCAGCAGCTGGATTTCTTATGGAACCCTCTGCTTTGAACCCACTTCAGGAATCGAGAAGTCACTATCCCATCTGGCCCCAAATTTTGAAACAATTATTTCTGATGACGATTTAACCCAGCTTCCCTTTTCCCACACAGTTACCACTGCGGATATTCTCACTTAGGGCTTTAACATCCCCTCTTGAAAATTCCTAAATATTTGAAGAAAAATATTCCATGCATAGCATCCACTCCCAGCATCCTACACACATTCCTTACCTCTAGTATCTCTGGAAGGCACGTCCCAGTGGGACATCATTAGCTACCTTACATGCTCCTTTGCCATACATTTGCCTCTTTCTAACAGGTGGTATCTAAATGTGCTTGATGATGCACTGACATGGAACCACAACTTCCCTCTTTCTATATAATAGGCTCTCATTTATCATGTTAGCACTACATTTAATTTTTGGGAGAGTTTACACACTGTCTTTTGTCAGTCATTGTCATTGTGAAGCTAGAGAGTCCTCTTCTATTGTATACTGATAAGTCACATTTAATATCAATGCCTCCTATTAACCTCTCACTAAACTTCACCTTATAGTCCATCAGCATTAAAATCTCTCAAATTAAATTTTTTTCTCCATACATCTTTAGAACATATCCACTACCTGTATTAGTATCAAATCTTCCATGTGTAGAGTTGGGTCCTTCCTATGTGGCTTACCGTGTTTCTAAAATCAAGTAACACATCACACACTCTGACTACCTGCTTGTGATTTCTGAAGAATAGGCTTACTGGAGAGTCAAGTTTCTAAGGAAAAAAAAGAACCCCATCCCTGTATCCTGTCTTTTATTCTGATCCACAAAGTGATGCTGCAGGCATCCTAGGATGACCAGCAGGGACCTGGCCCCCTGAGCTTGAGGGATTTTTGTGTCTATCCTCAAAACTCAAGGGCTTCAAGAGCCCCATTTTCTTATTAAGCATTTTATCCCATACAAAAGTGCCGCAGCATGTGCAGAGATGTTAACCTGTTCAAAGAGGCTATTTTATCTGACAGTACCTTTGAAAGCTACCTGTAGTTGCCTGGAGCCGGTGGTGTCCAAATGCAGATTCACAATGCAGTGTTCCTATAGGAATCAAGTCAGAGTTCTGAAAATGTAGCCTTTTATGCAGAAGGTCTTCAAACACAGATGGTTGTCTAAGCAAGACTCACTGTGGTTCAGCTACACTAAAATATGTCTTACTTTCGCACAAAATTCAATTGGTGATGATAGCTAACTATGATAGGATATGGTCTCCCTCTGTGCTCTCCCCCACCCCATGACAACTGAGATGGAAAAAGCCAAAGCAGCAATATCTTCATGACAGTGTTGTCGAGCTCAGCAATAATTTCTGCATTGCAGATTCAATAGGAAGCACTCAGCCCTTCCTACACTTGACCTCCGTCAGTTAACAAACTGAACACTACACCGTCCTAAAATCTCTTTCCCCAAGAGATTCCTACTACACGGAGTGACTTCCCCAACCTGAGCTGGATAATCTTGCTATTGATCTGTCTTCCTATGAAGCAGCTCAACTTCACAACATGTCTGCTTCAGCAGGCCTTCACACTCACAGCAGAGATGAACTGGGCAGTGTGCCCCAAGGGTACACGGTGTGCTTACGGCCACACCTTTCTTTCACCAAGATCAAACTCAGAGGTGTCGTCTGGATTTTAGAGAGGAGACAGGGATGCTTAGTTGATCATTTCGGAAGCCTTGTTTTTGTTTTGTTTTTTCTCTTTTGTAACTGACAGGTGCCTATTATAATACAAAATATAGTGATTTTCATGATAATCTCAGGAGCTCAGAAAAATGAGGAAACTTCACTCTTAGAGATTAAGACTGTCTGGGGCTTGAGAAAGTGTCTGGTTGTGTATATGCCTGTGAAAGTTCCATCTCCCATTTCTTCTTACATTTGAATATAAAGACATTTTTTTTTCTCCTTCCCTCTTTGGACATTGCAG
Seq C2 exon
AGTATGTAGCGGGAAGATTTGGCCAAGATGACTCCACAGGATATGCGGCCTTTAGTGTTAATGATAATTATGGACAGAACTTCAGTCTTTCAATGTTTGTCCGAACACGTCAACCCCTGGGCTTACTTCTGGCTTTGGAAAATAGTACTTACCAGTATGTCAGTGTCTGGCTAGAGCACGGCAGCCTAGCACTGCAGACTCCAGGCTCTCCCAAGTTCATGGTAAACTTTTTTCTCAGTGATGGAAATGTTCACTTAATATCTTTGAGAATCAAACCAAATGAAATTGAACTGTATCAGTCTTCACAAAACCTAGGATTCATTTCTGTTCCTACATGGACAATTCGAAGAGGAGACGTCATCTTCATTGGTGGCTTACCTGACAGAGAGAAGACTGAAGTTTATGGTGGCTTCTTCAAAGGCTGTGTTCAAGATGTCAGATTAAACAGCCAGACTCTGGAATTCTTTCCCAATTCAACAAACAATGCATACGATGACCCAATTCTTGTCAATGTGACTCAAGGCTGTCCCGGAGACAACACATGTAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000063681:ENSMUST00000059825:6
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF126612=hEGF=PD(23.1=0.9),PF0000822=EGF=WD(100=7.8),PF0000822=EGF=WD(100=10.9),PF0221019=Laminin_G_2=WD(100=43.1),PF0000822=EGF=WD(100=9.7)
A:
NA
C2:
PF0221019=Laminin_G_2=WD(100=64.5),PF0000822=EGF=PU(3.3=0.5)
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Pre-implantation embryo development
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types