Special

MmuINT0050721 @ mm9

Intron Retention

Gene
ENSMUSG00000018581 | Dnahc11
Description
dynein, axonemal, heavy chain 11 [Source:MGI Symbol;Acc:MGI:1100864]
Coordinates
chr12:119122031-119125387:-
Coord C1 exon
chr12:119125145-119125387
Coord A exon
chr12:119122214-119125144
Coord C2 exon
chr12:119122031-119122213
Length
2931 bp
Sequences
Splice sites
5' ss Seq
AAGGTAAGA
5' ss Score
10.57
3' ss Seq
GTGTATCTTAATGTTTTAAGGTT
3' ss Score
7.08
Exon sequences
Seq C1 exon
ATCGAGGATGAAGTCATGCTGGCACCAGGATTTGCAGCCCCTCCCTACTCAGATTATTCTGGTTATCACCAGTACATAGAGGACACGTTGCCTCCAGAAAGCCCGGCACTGTATGGTCTCCACCCCAATGCTGAAATAGAGTTACTAACAGTGACATCCAACACGCTCTTCAGAACTCTGCTGGAGATGCAACCCAGGAATGCAGTCAGCCAAGAGGAACTGGGGCAGTCTACAGAAGACAAG
Seq A exon
GTAAGAAGGCCTTCCTTGTTATCTTCTTTAAAGTGAAGTGCACTAGTCTCAGTTATTGTCTATCTAAGTTAAGCTTTACCTGTGCCAACAGGCAGATAGCTGCCACCCAGATCAAGGTGTAAAACATTTCCAACTGCCCAGGATACTCATGCTCTTTGTGAGGGTACTTCTTGCTCCCCAAAGGTAACCAATATCCTGACCTCCATAACCACATACTGGATGGGTTAACACAGTAGTTATTGCCAGGCTCCTGACTCCACAGTAAATTTGTGAGATTCACCTGTTCGTTCAGATACCAATGGGTCATTTTTGTTTTGTGCTCTATTATAGGAATATGATTTTTATTTTACTGTGGGTGGTTATCTGAAGTGGCTCTTGGGTTTGTTTTACTGTTATGAATGTTACAACCATGACCATGACCATGACCCCACATAATCCTTTGTCAAAAGACAAACATTGACTTACTTCCAAAGTGGTTGGTAATCTGACATTCTCTGTGCTCACAAACGGGATTGCCAGACCGTAGGTCTGAGTCTTCAGATACAATGCCTCCTTTAGAGTCTGTTACGGATTAGCAGTCTCTGAGTGCTTATAACTTTGTGTTCCTTGCCTGGGTCATCAGCCTCTCTTCACAAGCAGATGGCCGATGGATGGATGGATGGATGGATGGATGGATGGATGGATGGATGGATGGAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATGATAGAAATTTTTACTTGCTCCACTTTCCTCTCTCCTTTTCTTACAGACTTGTACCAACTCTTTATTCTACATGCATATTCTCTGTCAGATACATGAATTGAATTAGAGACATAATCTCCAAATCCACGGCTGGCCCTTCACCATGGGGGGAGGGGTACAGGGGTAGAGCAGGCCATATTTACGGGTGGTTATCTGGAAGCTAAGAAGACATCAGGTGTTCTGCTCTATACCTCTCCACCATAGTCCTTTGAGGTAGGGCCTCACTGACCTGGAGCCTGACTGGCAGCCAGCAAATCCCAGCAATTCTCCTGTCTCTGCCTTCTACAGTGCTGGGGTTATAAACACCCAGCTTTTTATGTGGGTGTAGAGATCTGAATTTAGGACACCTGTCTGTGCAGCTTTTACCCACTGGCCACATTCTAGCCCTAGCCCTTCACTTTTGCTGTATTTCTTGCTGTTATTTTGTTATTTTTCCCTTTTATATATCTTTGAAGATTTTTATATGCTCCATTATATAGAATTGTAGAAATGGAAAATGCTATTTCTTACATTAAAATCTTGTTTCTCTTTACTTTAAACCCTGAATAGTTCACCCTGCCAAACAAATGAGCTGTTACTCTTCTCAAAATTATTAAGCCAAGTGTGACTGCCAAAGATTCAGGATGTTCAGATGACACTTGTTAGCATGACCTCTAAGTCCCACAATATGGCCATATTATTTCTTGTATCTTTTAAAATAAGGTCATTCATTGACCTACTCATAACTTCAAAGAAATTGTACATGTTGTTTACCCTGAATATAAACATCTTTTCTACAATACTATATCTTTAGCAAGATGAACAAGGAAACATCTTCCCTGCAGGAAGACATACATTTATAGAAGCAGAGGGGCATATATTTATATTATATTATAAATCTTATATTTGTTATATTTCCAATCTTTCCATGAGGGAAGCCAATCACAAAACCAGAAAATGCAGTACATGTAAAGCAAGGTACCTCTGTATCCACCCAGGCCAGATGCTCATAGCCAAGGCCAGTTGTTAGGTGCCAGACACTAAAGAGCATACTTTTCCCTGGGCTATTTAACACACAAGGGTTTGGAGAGGCATTAGGATCTATTCCAGCTGACATGAGTTGCCAAGACTCAACAGGTAGAGAGAGGTCAGGGAAGGAAATGAAACCTGGCCGAGTCTAAAGCCATACTGCCATCTAACTACAGGGCCCTTGCCCACTGCCTACCCTGCTTGCGACAGCAATTCCTGGGCATGATGTTGGGACCATGTGAATCAACTGAGAAATGCAGGGAGATGGAAATGCTGCCTGGAGATAAAGGCCCTTTTTTCTTTTTTTTCTCTCCTGCCCCCTATTTTTTACTTTCTTTTTTTTTTTTTTTTTTCTTTTTGGCTCTTGGAGGCAGGGTCTCACTGCATATCTCAGGCTGGACTTGAACTCATGACCCTTCTTTCTTGGTCTCATGAAGGCTAGAATTCTAGGAAGGGTATTTCCCAATCATCTGCTTCTAGATAGTTATATTCTAGCTCAGTGAAACTGATAGATACGTACATTTTCAAATCAACAGTCATGTTCTACTCTCTCATCTTTACCTTTGCACACAAATGTCATTTAGATGGTAATCCTACTCCTTAAAACTGTCCACAGCAGAGGGGGGTGCCTAGTGCTAACGCAGCAGCTCTGAGCAGCTAACAATGGAGATCTTTTGAATGTTGTAGACATCTTTGGAAGCTGCATGGTCTATTCTGAGATGTCAAAAAGTATGATGTAGAGTCACTGTGTTAGTTAGGGTTTTATTGCTGTGAAAAAGACACCATGACCACAGCAACTTTTATAAAGAAAGCATTTAACTGGGACTGGCTTGCATTTCAAAGGTTAAGTCCATTATTGTCATGGTGGGGAGCATGGCTGTCCAGACAACTGGAGAAGGAGTCCAGAGTTTTACAAGTGGATTACAGGCAACAGGAAGAAAACAGACTCTGGGCCTGGCTTGAGCAGTTGAAGCCTCAAAGCTCACCCCCAGTGACACACTTCCTCCTACAAGGTCACACCTCCTAATAGTGCCACTACCTATGAGCCTATGGGGACCATACTCGTTCAAACCATCACAGACACCAGGAACAGCAACAAGAACAACAACAAAAGAAATACAGTCTGTGTATCTTAATGTTTTAAG
Seq C2 exon
GTTAAGAATATCTTGGATGACATTTTGGAGAGACTTCCAGAAGAGTTCAACATGGCAGAAATAATGCAAAAGAACCCAAATAGAAGCCCGTATGTTCTCGTTTGCTTTCAAGAGTGTGAGAGGATGAACGTTCTCATCCGGGAAATCCGTGTGTCGCTTCAACACTTAGACCTTGGTTTGAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000018581-Dnahc11:NM_010060:77
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact





	

	
ORF disruption upon sequence inclusion





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.111 A=NA C2=0.016
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
PF0302810=Dynein_heavy=FE(11.4=100)

							
A:
NA

							
C2:
PF0302810=Dynein_heavy=FE(8.5=100)

						

					

				








    
Main Inclusion Isoform:
NA





     
                   









    
Main Skipping Isoform:
ENSMUSP00000081867





     
      









    
Other Inclusion Isoforms:
NA
          









    
Other Skipping Isoforms:
NA
  



Associated events






Other assemblies


mm10




Conservation


Human
(hg38)
chr7:21892668-21894622 
ALTERNATIVE
HsaINT0049365
(DNAH11)
Human
(hg19)
chr7:21932286-21934240 
ALTERNATIVE
HsaINT0049365
(DNAH11)
Rat
(rn6)
chr6:145790414-145793216 
LOW PSI
RnoINT0048712
(Dnah11)
Cow
(bosTau6)
chr4:30784310-30788496 
ALTERNATIVE
BtaINT0050307
(DNAH11)
Chicken
(galGal4)
chr18:10095459-10096352 
LOW PSI
GgaINT1011544
(DNAH17)
Chicken
(galGal3)
chr18:1176946-1179121 
LOW PSI
GgaINT0127399
(DNAH9)
Zebrafish
(danRer10)
chr6:10354112-10357960 
DreINT0058357
(dnah9l)
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
No suggested primer sequences

				
R: 
No suggested primer sequences

				
Band lengths: 

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Pre-implantation embryo development
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types






Retrieved from "https://vastdb.crg.eu/wiki/Special:VastDB"